The pathological findings of placenta with neonatal placenta
We present a case of the newborn with neonatal lupus syndrome. She had skin lesion, cardiac, hepatic (elevated hepatic enzyme), and hematologic findings. Neonatal lupus syndrome was diagnosed on the basis of the elevated anti-SSA and SSB antibodies. The placenta weighted 285g and cut surface showed anemic. Histologically, these chorionic villi demonstrated the shrinkage of capillaries. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Yuichiro Sato Source Type: research
Effects of TNF- α and IGF-I on proliferation and angiogenesis of BeWo cells
Objectives: Obesity in pregnancy is implicated in placental hypertrophy, leading to macrosomic infants. Obesity has been considered as chronic inflammation with the evidence of elevated inflammatory cytokine, TNF- α. However, the effects of TNF-α at the physiological concentrations (1-10pg/m) on placental development are unknown. In addition, it has been known that IGF-I is also elevated in obesity. We investigated the effects of TNF-α and IGF-I on proliferation and angiogenesis of trophoblast cells by usi ng the human choriocarcinoma cell-line, BeWo. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Kei Tanaka Source Type: research
One FGR fetus with placental mesenchymal dysplasia in Dichorionic Diamniotic twin pregnancy
We reported a case in which one FGR fetus showed PMD in a dichorionic-diamniotic (DD) twin pregnancy. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Shoko Jitsumori Source Type: research
Effect of PTCH1 expression on placental and fetal growth in rats treated with retinoic acid
Objective: Pacthed-1 (PTCH1) suppresses hedgehog signaling. Decreased expression of PTCH1 induces Gli1, a downstream transcription factor, leading to cell proliferation. Retinoic acid (RA) has been reported to induce PTCH1 expression. Since RA administration induce myelomeningocele rat model with low birth weight, we investigated an inhibitory effect on placental and fetal growth by PTCH1 expression due to RA administration to elucidate one of the causes of fetal growth restriction. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Kazuhiro Kajiwara Source Type: research
Conservative management of a retained placenta: A report of five cases
Objective: To clarify the risk factors for successful conservative treatment of retained placenta after vaginal delivery. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Mari Tomiie Source Type: research
Regulatory mechanism of CD59 expression on human extravillous trophoblast
Objective: In human placenta, endovascular extravillous trophoblast (eEVT) makes direct contact with complement components contained in the maternal blood. Although activated complement components could exert the cytotoxic effects, eEVT is not eliminated by their activation. We focused on possible avoidance mechanism inherent in eEVT. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Masashi Ueda Source Type: research
Extra-abdominal umbilical vein varix with thrombosis. A case report
We present a case diagnosed extra-abdominal UVV with thrombosis. UVV was detected at 23 weeks of gestation for the first time by ultrasonographic screening. She required hospital care to monitor the alteration of UVV frequently after 29 weeks of gestation. Increased edematous UVV was detected at 32 weeks of gestation by ultrasonography. On the same day, we performed emergent cesarean section to avoid acute additional risks of umbilical cord occlusion. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Yuuki Matsumoto Source Type: research
A case of Breu ’s mole associated with selective fetal growth restriction in dichorionic diamniotic twins
We report a case of selective fetal growth restriction (FGR) in dichorionic diamniotic twins (DD twins), in which ultra sound test revealed a massive hematoma in the placenta of the smaller fetus suspected to be Breu’s mole. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Baku Nakakita Source Type: research
Clinical course of chronic abruption-oligohydramnios sequence: A report of four cases
Introduction: Chronic abruption-oligohydramnios sequence (CAOS) is a rare complication of pregnancy diagnosed as follows: 1) genital bleeding lasting more than 7 days, 2) normal amniotic fluid volume when genital bleeding starts, and 3) oligohydramnios without any symptoms of preterm premature rupture of membranes (pPROM). Diffuse chorioamniotic hemosiderosis (DCH) is detected in most cases of CAOS. Here we report the clinical course and pathological findings in four cases of CAOS. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Yamamura Michihiro Source Type: research
Characteristic fine structures of uterine activity of a pregnant great white shark
Objectives: A female great white shark weighing 1,526kg was caught by a drift-net fishing in the Okinawa islands sea. She was pregnant and had each 3 siblings in the both side of the uterus without placentation. The uterus contained large amount of milk and egg-shells. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Kokuba Hiroko Source Type: research
Discordant karyotype in monochorionic diamniotic twins: two cases report
Monochorionic diamniotic (MD) twins are usually monozygotic twins, that is, their karyotype is match. Nevertheless, some discordant karyotype of MD twins have been reported. As the reasons there are such as twins generated via binovular follicle fertilization (dizygotic) and trisomy rescue. Case 1 was conceived MD twins spontaneously. But ultrasound showed the fetuses were discordant for gender. Delivery in pregnancy 38 weeks, they seemed normal girl and boy. The karyotype of umbilical cord blood was 46,XX[15]/46,XY[15] in the girl and 46,XY[21]/46,XX[9] in the boy. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Atsuko Hichijo Source Type: research
Decidual natural killer cells express glucose transporter type 1 (Slc2a1) during mouse pregnancy
In this study, we performed quantitative analysis of Slc2a1-positive cells. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Chaw Kyi-Tha-Thu, Toshihiro Takizawa Source Type: research
PPAP scoring system predicts adherent placenta in women with placenta previa
Objective: Adherent placenta (AP) is a life-threatening condition, and is often complicated with placenta previa (PP). We have devised an original scoring system for predicting AP complicated with PP, and conducted a prospective cohort study to evaluate the diagnostic accuracy of our scoring system (Placenta Previa with Adherent Placenta score: PPAP score). (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Kenji Tanimura Source Type: research
A case of pregnancy with placenta previa accreta terminated at 16th weeks of gestation, and placental proteomic analysis
Introduction: Placenta accreta is one of fatal obstetric complications, while its pathophysiology remains unestablished, and prediction of its onset is usually difficult. We experienced a case of placenta previa accreta where we successfully suspected it, and performed placental proteomic analysis of the case. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Yoshinori Moriyama Source Type: research
Pregnancy after Uterine Artery Embolization caused abnormal placenta and postpartum hemorrhage
Background: Interventional Radiology (IVR) is one of useful treatments of postpartum hemorrhage (PPH) and is also recommended in ”guidelines for obstetric critical bleeding 2017 in Japan”. Although it is a procedure that enables fertility preservation. There are many papers reported on the effect of IVR on fertility or menstruation, but the effect on perinatal outcomes remains unclear. The aim of this study is to investig ate the mother and neonate outcomes with the previous history of IVR. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Masataka Nomoto Source Type: research
