Torsion of the umbilical cord as cause of stillbirth
In this study I examine the rate of stillbirths related to umbilical torsion. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Masayoshi Arizawa Source Type: research

Placental pathology in the diagnosis and treatment of TAM
Object: I have three distinct objects in this paper (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Masayoshi Arizawa Source Type: research

Repeated phylogeny on the ontogeny of Silvertip shark Carcharhinus albimarginatus fetuses. Morphological discussions from Evo-Devo perspectives.
Objectives: Elasmobranchs (sharks, skates and rays) display a wide variety of reproductive modes. Silvertip shark Carcharhinus albimarginatus belongs to a group of placental viviparity. Fetuses in this group is connected to the external yolk sac by the yolk stalk in the early stage of development. After terminal differentiation of Yolk sacs into the placentae, the yolk stalks make remarkable metamorphosis in their internal structure and differentiated into elongated umbilical cord. However this process is not so far examined. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Wahei Yoshida Source Type: research

Normal fetus having a positive-result of non-invasive prenatal testing (NIPT) due to confined placental mosaicism
We report a normal fetus having a false positive-result of non-invasive prenatal testing (NIPT) due to confined placental mosaicism (CPM). (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Kiyonori Miura Source Type: research

The patho-mechanism of incarceration of the gravid uterus; the pelvic structure and the placental position. A two-case report and review of literature.
Incarceration of the gravid uterus describes an extremely rare situation where a retroverted or retroflexed gravid uterus fails to ascend into the abdominal cavity. This is an uncommon presentation and is said to occur in 0.3% of pregnancies. If the placenta is located in the fundus of an incarcerated uterus and the physician is unaware of this obstetric disorder, the ultrasound and/or MRI findings may be misinterpreted as a placenta previa. Although the causes of the incarcerated gravid uterus were unknown, here we investigate the involvement of the pelvic structure and placental site to the patho-mechanism of incarcerati...
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Chisato Motooka Source Type: research

Proton Pump Inhibitors Quench the Pathophysiological Characteristics of Preeclampsia in Both Human and Mouse Models and Represent an Exciting Novel Candidate Therapeutic
Preeclampsia (PE) is a serious complication of pregnancy. Two of the major pathophysiological aspects are 1) the release of sFlt-1 and sEng and 2) maternal endothelial dysfunction leading to hypertension and major end organ damage. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Kenji Onda Source Type: research

Sonic hedgehog pathway regulates IGF1R expression in placenta
Objective: We previously reported that Sonic hedgehog(=Shh) pathway was involved in preeclamptic placentas. The aim of this study is to elucidate the association between Shh pathway and placental growth factor(=PlGF) in placenta. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Hiroshi Takai Source Type: research

The medical application of the studies using transposon
Transposons are nucleotide sequences capable of transposition within the genome in a cell. They are also called jumping genes or transposable elements and are classified into deoxyribonucleic acid (DNA)[A1] transposons, in which DNA fragments transpose directly, and ribonucleic acid (RNA) transposons, retrotransposons[A2] , which undergo transposition and reverse transcription. Transposition of a DNA transposon requires a transposition enzyme called transposase, which is encoded by the transposon itself. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Yoshichika Suzuki Source Type: research

A case of uterine inversion complicated with placenta accreta
We report a case of acute inversion of the uterus in which we successfully perform a manual vaginal reposition of the uterus. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Akari Watanabe Source Type: research

Medical application of the studies using transposons
Transposons are nucleotide sequences capable of transposition within the genome in a cell. They are also called jumping genes or transposable elements and are classified into deoxyribonucleic acid (DNA) transposons, in which DNA fragments transpose directly, and ribonucleic acid (RNA) transposons, retrotransposons, which undergo transposition and reverse transcription. Transposition of a DNA transposon requires a transposition enzyme called transposase, which is encoded by the transposon itself. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Yoshichika Suzuki Source Type: research

Abstracts author index
(Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Source Type: research

Title Page/Editorial Board
(Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Source Type: research

IFPA Pages
(Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Source Type: research

Role of nucleoside transporters in transplacental pharmacokinetics of nucleoside reverse transcriptase inhibitors zidovudine and emtricitabine
Zidovudine (AZT) and emtricitabine (FTC) are effective and well tolerated antiretroviral drugs, routinely used in the prevention of perinatal HIV transmission. However, precise mechanism(s) involved in their transfer from mother to fetus are not fully elucidated. Since both drugs are nucleoside analogues, we hypothesized that the mechanisms of their transplacental passage might include equilibrative nucleoside transporters, ENT1 and/or ENT2. (Source: Placenta)
Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: S. Karbanova, L. Cerveny, M. Ceckova, Z. Ptackova, L. Jiraskova, S. Greenwood, F. Staud Source Type: research

DNA methylation of amino acid transporter genes in the human placenta
This study investigates the DNA methylation status of amino acid transporters and their expression across gestation in human placenta. (Source: Placenta)
Source: Placenta - October 31, 2017 Category: Reproduction Medicine Authors: C. Simner, B. Novakovic, K.A. Lillycrop, C.G. Bell, N.C. Harvey, C. Cooper, R. Saffery, R.M. Lewis, J.K. Cleal Source Type: research