The proteome of fetal fluids in mares with experimentally-induced placentitis
Placental inflammation (placentitis) is one of the leading causes of late-term abortion in mares. Although prognosis is good assuming early diagnosis and treatment, diagnostics are limited. (Source: Placenta)
Source: Placenta - March 19, 2018 Category: Reproduction Medicine Authors: S.C. Loux, B.A. Ball Source Type: research
Oxidative stress in placental pathology
The most important function of the placenta is the exchange of nutrients and oxygen between a mother and her fetus. To establish a healthy functioning placenta, placentation needs to occur with adequate remodelling of spiral arteries by extravillous trophoblasts. When this process is impaired, the resulting suboptimal and inadequate placenta function results in the manifestation of pregnancy complications. Impaired placenta function can cause preeclampsia and leads to fetal growth restriction due to hypoxia. (Source: Placenta)
Source: Placenta - March 16, 2018 Category: Reproduction Medicine Authors: Mirthe H. Schoots, Sanne J. Gordijn, Sicco A. Scherjon, Harry van Goor, Jan-Luuk Hillebrands Source Type: research
Genetic and microscopic assessment of the human chemotherapy-exposed placenta reveals possible pathways contributive to fetal growth restriction
Fetal growth restriction (FGR) carries an increased risk of perinatal mortality and morbidity. A major cause of FGR is placental insufficiency. After in utero chemotherapy-exposure, an increased incidence of FGR has been reported. In a prospective cohort study we aimed to explore which pathways may contribute to chemotherapy-associated FGR. (Source: Placenta)
Source: Placenta - March 8, 2018 Category: Reproduction Medicine Authors: M. Verheecke, A. Cort ès Calabuig, J. Finalet Ferreiro, V. Brys, R. Van Bree, G. Verbist, T. Everaert, L. Leemans, M.M. Gziri, I. Boere, M.J. Halaska, J. Vanhoudt, F. Amant, K. Van Calsteren Source Type: research
Placental lipoprotein lipase activity is positively associated with newborn adiposity
Recent data suggest that in addition to glucose, fetal growth is related to maternal triglycerides (TG). To reach the fetus, TG must be hydrolyzed to free fatty acids (FFA) and transported across the placenta, but regulation is uncertain. Placental lipoprotein lipase (pLPL) hydrolyzes TG, both dietary chylomicron TG (CM-TG) and very-low density lipoprotein TG (VLDL-TG), to FFA. This may promote fetal fat accretion by increasing the available FFA pool for placental uptake. We tested the novel hypothesis that pLPL activity, but not maternal adipose tissue LPL activity, is associated with newborn adiposity and higher maternal...
Source: Placenta - March 5, 2018 Category: Reproduction Medicine Authors: Margaret J.R. Heerwagen, Diane L. Gumina, Teri L. Hernandez, Rachael E. Van Pelt, Anita W. Kramer, Rachel C. Janssen, Dalan R. Jensen, Theresa L. Powell, Jacob E. Friedman, Virginia D. Winn, Linda A. Barbour Source Type: research
Placental function and structure at term is altered in broodmares fed with cereals from mid-gestation
Feeding pregnant broodmares with cereal concentrates has been shown to increase maternal insulin resistance and affect foal metabolism in the short and long-term. These effects are likely to be mediated by the placenta. Here, we investigated feto-placental biometry and placental structure and function at term in mares fed with or without cereals concentrates. (Source: Placenta)
Source: Placenta - March 3, 2018 Category: Reproduction Medicine Authors: M. Robles, P. Peugnet, C. Dubois, F. Piumi, L. Jouneau, O. Bouchez, M.C. Aubri ère, M. Dahirel, J. Aioun, L. Wimel, A. Couturier-Tarrade, P. Chavatte-Palmer Source Type: research
Title Page/Editorial Board
(Source: Placenta)
Source: Placenta - February 25, 2018 Category: Reproduction Medicine Source Type: research
IFPA Pages
(Source: Placenta)
Source: Placenta - February 25, 2018 Category: Reproduction Medicine Source Type: research
Placental exosomes profile in maternal and fetal circulation in intrauterine growth restriction - Liquid biopsies to monitoring fetal growth
The objective of this study was to quantify the concentration of total and placenta-derived exosomes in maternal and fetal circulation in small fetuses classified as FGR or small for gestational age (SGA). (Source: Placenta)
Source: Placenta - February 24, 2018 Category: Reproduction Medicine Authors: Jezid Miranda, Cristina Paules, Soumyalekshmi Nair, Andrew Lai, Carlos Palma, Katherin Scholz-Romero, Gregory E. Rice, Eduard Gratacos, Fatima Crispi, Carlos Salomon Source Type: research
A novel scoring system for predicting adherent placenta in women with placenta previa
Placenta previa (PP) is one of the most significant risk factors for adherent placenta (AP). The aim of this study was to evaluate the diagnostic efficacy of a novel scoring system for predicting AP in pregnant women with PP. (Source: Placenta)
Source: Placenta - February 21, 2018 Category: Reproduction Medicine Authors: Kenji Tanimura, Mayumi Morizane, Masashi Deguchi, Yasuhiko Ebina, Utaru Tanaka, Yoshiko Ueno, Kazuhiro Kitajima, Tetsuo Maeda, Kazuro Sugimura, Hideto Yamada Source Type: research
IFN τ mediates chemotaxis, motility, metabolism and CK18 downregulation in bovine trophoblast cells in vitro via STAT1 and MAPK42/44 signaling
IFN τ is the ruminant pregnancy recognition signal. In the study we investigated the autocrine influence of IFNτ on bovine F3 trophoblast cells. In detail chemotaxis, motility, metabolism, cell polarisation (CK18; ezrin) and the underlying classical (STAT1) and non-classical (MAPK42/44) signaling path ways were examined. (Source: Placenta)
Source: Placenta - February 20, 2018 Category: Reproduction Medicine Authors: C. Loch, J.-D. Haeger, C. Pfarrer Source Type: research
Hematopoietic changes in the offspring induced by maternal overweight: Effect on placenta and fetal liver populations
Bone marrow cells (BMC) from obese adult mice display an increased apoptosis rate over proliferation. Hematopoietic stem cells (HSC) form all blood cells and are important BMC used in cell therapy. Because it is known that prenatal development can be affected by adverse metabolic epigenetic programming from the maternal organism, this work aimed to investigate the effects of maternal overweight on placenta and fetal liver hematopoietic niches. (Source: Placenta)
Source: Placenta - February 12, 2018 Category: Reproduction Medicine Authors: Luana Leir ós, Juliana Barbosa Torreão Dáu, Daphne Pinheiro, Ana Carolina Stumbo Machado, Alessandra Alves Thole, Erika Afonso Costa Cortez, Laís de Carvalho, Simone Nunes de Carvalho Source Type: research
Chronic histiocytic intervillositis – Clinical, biochemical and radiological findings: An observational study
This study aims to determine clinical, biochemical and radiological factors associated with CHI, to guide management of subsequent pregnancies. (Source: Placenta)
Source: Placenta - February 6, 2018 Category: Reproduction Medicine Authors: Lawrence Koby, Sarah Keating, Ann Kinga Malinowski, Rohan D'Souz Source Type: research
The placental component and neonatal outcome in singleton vs. twin pregnancies complicated by gestational diabetes mellitus
We aimed to compare placental histopathological lesions and neonatal outcome in singleton vs. twin pregnancies complicated by gestational diabetes mellitus (GDM). (Source: Placenta)
Source: Placenta - February 1, 2018 Category: Reproduction Medicine Authors: Eran Weiner, Elad Barber, Ohad Feldstein, Letizia Schreiber, Ann Dekalo, Yossi Mizrachi, Jacob Bar, Michal Kovo Source Type: research
Diagnostic performance of uric acid for prediction of preeclampsia
Although it is well-established the relationship between uric acid levels (UA) and preeclampsia, its clinical utility is still controversial. (Source: Placenta)
Source: Placenta - February 1, 2018 Category: Reproduction Medicine Authors: A. Corominas, S. Balconi, M. Ort íz, N. Martinez, A.E. Damiano Source Type: research
