Discordant karyotype in monochorionic diamniotic twins: two cases report

Monochorionic diamniotic (MD) twins are usually monozygotic twins, that is, their karyotype is match. Nevertheless, some discordant karyotype of MD twins have been reported. As the reasons there are such as twins generated via binovular follicle fertilization (dizygotic) and trisomy rescue. Case 1 was conceived MD twins spontaneously. But ultrasound showed the fetuses were discordant for gender. Delivery in pregnancy 38 weeks, they seemed normal girl and boy. The karyotype of umbilical cord blood was 46,XX[15]/46,XY[15] in the girl and 46,XY[21]/46,XX[9] in the boy.

Source: Placenta - November 1, 2017 Category: Reproduction Medicine Authors: Atsuko Hichijo Source Type: research