Front cover: Bioavailability of Terpenes and Postprandial Effect on Human Antioxidant Potential. An Open ‐Label Study in Healthy Subjects
Mol. Nutr. Food Res. 2018, 62, 1700751
DOI: 10.1002/mnfr.201700751
The bioavailability of terpenes highly present in foods of plant origin is investigated. Mastiha, a natural medicinal herb of the Mediterranean basin, is administered per os in healthy humans. Results show that terpenes mastihadienonic (MNA), isomastihadienonic (IMNA) moronic acid (MA), and oleanonic acid (OLEA) are detected and quantified in human plasma and also exhibit favorable effects on oxidative stress. (Source: Nahrung / Food)
Source: Nahrung / Food - February 7, 2018 Category: Nutrition Authors: Efstathia Papada, Aristea Gioxari, Vincent Brieudes, Charalampia Amerikanou, Maria Halabalaki, Alexios Leandros Skaltsounis, Ilias Smyrnioudis, Andriana C. Kaliora Tags: Front Cover Source Type: research
Comparative Study of Different Polar Groups of EPA ‐Enriched Phospholipids on Ameliorating Memory Loss and Cognitive Deficiency in Aged SAMP8 Mice
Conclusion: These data suggested that EPA‐PS exhibited better effects than EPA‐PC/PE on ameliorating memory and cognitive function, which might be attributed to the phospholipid polar groups.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 3, 2018 Category: Nutrition Authors: Miao ‐miao Zhou, Hong‐xia Che, Jia‐qi Huang, Tian‐tian Zhang, Jie Xu, Chang‐hu Xue, Yu‐ming Wang Tags: RESEARCH ARTICLE Source Type: research
Caffeic Acid Phenethyl Ester Improves Metabolic Syndrome by Activating PPAR γ and Inducing Adipose Tissue Remodeling in Diet‐Induced Obese Mice
ConclusionCAPE ameliorates metabolic disease by inducing PPARγ activity and AT remodeling. Additionally, study reveals that the intake of CAPE after obesity, as well as in the early stage of obesity, helps in the prevention and treatment of MetS.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 1, 2018 Category: Nutrition Authors: Soon ‐Hee Kim, Hee‐Sook Park, Moon Ju Hong, Haeng Jeon Hur, Dae Young Kwon, Myung‐Sunny Kim Tags: Research Article Source Type: research
Hypolipidemic and Antioxidant Properties of Oryzanol Concentrate in Reducing Diabetic Nephropathy via SREBP1 Down Regulation Rather than Beta Oxidation
ConclusionOryzanol concentrate having hypolipidemic and antioxidant properties, also down regulated the lipid biosynthesis through reduced SREBP1–TGF‐β interactions (EMSA) and could effectively ameliorate DN. Gene (ACC2, Cpt1 & ACOX) expression studies showed that β‐oxidation was not involved in reducing DN.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 1, 2018 Category: Nutrition Authors: G. Bhaskaragoud, V. Geetha, T. Sharanappa, A. S. Mohan Kumar, C. Hema Kumar, G. Suresh Kumar Tags: Research Article Source Type: research
Probiotics Affect One ‐Carbon Metabolites and Catecholamines in a Genetic Rat Model of Depression
ConclusionsProbiotics reduced the flow of methyl groups via betaine, increased liver SAM, and decreased plasma dopamine and norepinephrine. Since these changes in methylation and catecholamine pathways are known to be involved in several diseases, future investigation of the effect of probiotics is warranted.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 1, 2018 Category: Nutrition Authors: Sandra Tillmann, Hussain M. Awwad, Amanda R. Eskelund, Giulia Treccani, Juergen Geisel, Gregers Wegener, Rima Obeid Tags: Research Article Source Type: research
Lipid ‐Modifying Effects of Chitosan Supplementation in Humans: A Pooled Analysis with Trial Sequential Analysis
ConclusionSupplementation with chitosan effectively reduces plasma concentrations of TC and LDL‐C. Current evidence indicates daily chitosan supplementation as a candidate for therapeutic lipid management strategies.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 1, 2018 Category: Nutrition Authors: Haohai Huang, Ying Zou, Honggang Chi, Dan Liao Tags: Research Article Source Type: research
Sodium Butyrate Inhibits Colorectal Cancer Cell Migration by downregulating Bmi ‐1 through enhanced miR‐200c expression
Conclusion: NaB inhibits CRC cell migration by enhancing miR‐200c expression mediated downregulation of Bmi‐1. These findings support the utility of NaB in colorectal cancer therapy.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 1, 2018 Category: Nutrition Authors: Zhiyao Xu, Jingjing Tao, Ping Chen, Long Chen, Sherven Sharma, Guanyu Wang, Qinghua Dong Tags: Research Article Source Type: research
Current Level of Fish Consumption is Associated with Mortality in Chinese but not US Adults: New Findings From Two Nationwide Cohort Studies With 14 and 9.8 years of Follow ‐Up
ConclusionIn these two nationwide cohort studies, fish consumption is associated with a reduced risk of total mortality for Chinese but not US populations.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 1, 2018 Category: Nutrition Authors: Pan Zhuang, Wenqiao Wang, Jun Wang, Yu Zhang, Jingjing Jiao Tags: Research Article Source Type: research
A Novel Antihypertensive Peptide Identified in Thermolysin ‐Digested Rice Bran
ConclusionWe identify a novel, orally active antihypertensive peptide, LRA from the digest of rice bran protein.
Thermolysin‐digested rice bran (TRB) decreases systolic blood pressure in spontaneously hypertensive rats (SHRs). TRB show a ACE inhibitory activity in vitro and in vivo, and reduced serum troponin I levels. A novel antihypertensive peptide, LRA from TRB, is also identified, and LRA is shown to be derived from At2g28490, the vicilin‐like seed storage protein. LRA (0.25 mg kg−1) decreases systolic blood pressure after oral administration. (Source: Nahrung / Food)
Source: Nahrung / Food - January 25, 2018 Category: Nutrition Authors: Naohisa Shobako, Yutaro Ogawa, Atsushi Ishikado, Kayo Harada, Etsuko Kobayashi, Hirohisa Suido, Takashi Kusakari, Mariko Maeda, Makoto Suwa, Motonobu Matsumoto, Ryuhei Kanamoto, Kousaku Ohinata Tags: RESEARCH ARTICLE Source Type: research
Response of Red Blood Cell Folate to Supplementation in Nonpregnant Women is Predictable: A Proposal for Personalized Supplementation
ConclusionsThe models can guide nutritional recommendations in women when baseline RBC‐folate concentrations are measured and the time to pregnancy between 4 and 8 weeks.
The response of blood folate to supplementation is predictable and enables guiding supplement recommendations and personalized supplementation when baseline RBC‐folate is available. (Source: Nahrung / Food)
Source: Nahrung / Food - January 22, 2018 Category: Nutrition Authors: Rima Obeid, Christiane Sch ön, Manfred Wilhelm, Rajiv P. Shrestha, Stefan Pilz, Klaus Pietrzik Tags: RESEARCH ARTICLE Source Type: research
Human Milk Oligosaccharides as Promising Antivirals
This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - January 16, 2018 Category: Nutrition Authors: Vasily Morozov, Grant Hansman, Franz ‐Georg Hanisch, Horst Schroten, Clemens Kunz Tags: Review Source Type: research
Antimicrobial Emulsifier –Glycerol Monolaurate Induces Metabolic Syndrome, Gut Microbiota Dysbiosis, and Systemic Low‐Grade Inflammation in Low‐Fat Diet Fed Mice
ConclusionOur results indicate that relatively low‐dose GML consumption promotes metabolic syndrome, gut microbiota dysbiosis, and systemic low‐grade inflammation, thereby calling for a reassessment of GML usage.
Glycerol monolaurate (GML) induced metabolic syndrome, gut microbiota dysbiosis, and circulating low‐grade inflammation by significantly increasing the body fat percentage and epididymal fat; exacerbating serum lipid profiles disorder and histopathologic abnormality of epididymal adipose tissue; changing the composition and metabolic function of gut microbiota; and upregulating the production of the serum l...
Source: Nahrung / Food - January 9, 2018 Category: Nutrition Authors: Zengliang Jiang, Minjie Zhao, Hui Zhang, Yang Li, Mengyun Liu, Fengqin Feng Tags: RESEARCH ARTICLE Source Type: research
In Vitro Effects of Serotonin, Melatonin, and Other Related Indole Compounds on Amyloid ‐β Kinetics and Neuroprotection
ConclusionMelatonin and other related indolic compounds, mainly serotonin, show an inhibitory and destabilizing effect on amyloid‐β peptide fibril formation and they possess neuroprotective properties related to the vitagenes system.
Melatonin is a neurohormone derived from tryptophan in a multistep process involving serotonin and other intermediates which are present in food. In this work, the protective effects against amyloid‐β aggregation and cytotoxicity of eight indolic compounds are evaluated. The present study shows that serotonin is the most effective compound to inhibit amyloid‐β peptide aggregation. Al...
Source: Nahrung / Food - January 4, 2018 Category: Nutrition Authors: Ruth Hornedo ‐Ortega, Grégory Da Costa, Ana B. Cerezo, Ana M. Troncoso, Tristan Richard, M. Carmen Garcia‐Parrilla Tags: RESEARCH ARTICLE Source Type: research
Kefir Peptides Prevent Hyperlipidemia and Obesity in High ‐Fat‐Diet‐Induced Obese Rats via Lipid Metabolism Modulation
ConclusionThese results demonstrate that kefir peptides treatment improves obesity via inhibition of lipogenesis, modulation of oxidative damage, and stimulation of lipid oxidation. Therefore, kefir peptides may act as an anti‐obesity agent to prevent body fat accumulation and obesity‐related metabolic diseases.
The effects of kefir peptides on obese rats may occur through the inhibition of lipogenesis pathway by reduced the FAS enzyme and increased the p‐ACC protein and stimulation of the lipid oxidation pathway via increased expression of p‐AMPK, PPAR‐α, and CPT1. Administration of kefir peptides also signifi...
Source: Nahrung / Food - January 2, 2018 Category: Nutrition Authors: Yu ‐Tang Tung, Hsiao‐Ling Chen, Hsin‐Shan Wu, Mei‐Hsuan Ho, Kowit‐Yu Chong, Chuan‐Mu Chen Tags: FOOD & FUNCTION Source Type: research
Increased Levels of 27 ‐Hydroxycholesterol Induced by Dietary Cholesterol in Brain Contribute to Learning and Memory Impairment in Rats
ConclusionsThis study indicates that the mechanisms of dietary cholesterol on learning and memory impairment may be involved in cholesterol metabolism and lysosome function with the increase of plasma 27‐OHC, thus resulting in Aβ formation and accumulation.
Increased levels of 27‐hydroxycholesterol induced by dietary cholesterol in brain impairs the learning and memory of rats via disrupting cholesterol metabolism and lysosome dysfunction, resulting in Aβ formation and accumulation. (Source: Nahrung / Food)
Source: Nahrung / Food - January 2, 2018 Category: Nutrition Authors: Xiaona Zhang, Chenyan Lv, Yu An, Quanri Liu, Hongguo Rong, Lingwei Tao, Ying Wang, Yushan Wang, Rong Xiao Tags: RESEARCH ARTICLE Source Type: research
