Bioaccessibility, bioavailability, and anti ‐inflammatory effects of anthocyanins from purple root vegetables using mono‐ and co‐culture cell models
ConclusionAnthocyanins from purple carrots and potatoes possess a promising anti‐inflammatory effect in model gut system. They can be absorbed and act differently but are in general beneficial for inflammation‐mediated diseases.
Bioavailability of purple carrot and purple potato derived anthocyanins in human intestinal systems and their anti‐inflammatory actions are investigated. Two identified anthocyanins, cyanidin‐3‐O‐(2″‐xylosyl‐6″‐(6″′‐feruloyl‐glucosyl)‐galactoside and petunidin‐3‐O‐(p‐coumaroyl)‐rutinoside‐5‐O‐glucoside, derived from purple carrot and potato, respecti...
Source: Nahrung / Food - August 29, 2017 Category: Nutrition Authors: Hua Zhang, Hassan Yousef, Justin Renaud, Ronghua Liu, Cheng Yang, Yong Sun, Rong Tsao Tags: Research Article Source Type: research
Dual function of Lactobacillus kefiri DH5 in preventing high ‐fat‐diet‐induced obesity: direct reduction of cholesterol and upregulation of PPAR‐α in adipose tissue
ConclusionL. kefiri DH5 exerts anti‐obesity effects by direct reduction of cholesterol in the lumen and upregulation of PPAR‐α gene in adipose tissues.
The proposed dual mechanism underlying the anti‐obesity and anti‐non‐alcoholic fatty liver disease (NAFLD) effects of L. kefiri DH5 in high‐fat diet (HFD)‐fed mice was explored. A large proportion of the orally administered L. kefiri DH5 remains active and viable in the gastrointestinal tract and exerts potent anti‐obesity effects in HFD‐fed mice via a dual mechanism: (i) direct reduction of excessive cholesterol in the lumen to decrease overall fat infl...
Source: Nahrung / Food - August 29, 2017 Category: Nutrition Authors: Dong ‐Hyeon Kim, Dana Jeong, Il‐Byeong Kang, Hyunsook Kim, Kwang‐Young Song, Kun‐Ho Seo Tags: Research Article Source Type: research
Modulation of starch digestibility in breakfast cereals consumed by subjects with metabolic risk: impact on markers of oxidative stress and inflammation during fasting and the postprandial period
Conclusion: Consumption of HSDS products for 3 weeks significantly altered both postprandial glycaemia and insulinaemia, but was not sufficient to modify the inflammatory profile. Consumption of both cereal products was associated with a slightly higher fasting oxidative stress profile.
This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - August 1, 2017 Category: Nutrition Authors: St éphanie Lambert‐Porcheron, Sylvie Normand, Emilie Blond, Monique Sothier, Hubert Roth, Alexandra Meynier, Sophie Vinoy, Martine Laville, Julie‐Anne Nazare Tags: Research Article Source Type: research
Appetite ‐Inducing Effects of Homoeriodictyol: Two Randomized, Cross‐Over Interventions
ConclusionsNaHED demonstrated appetizing effects in healthy adults when administered with a glucose load. Long‐term intervention studies are warranted to verify these effects in compromised subjects.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - August 1, 2017 Category: Nutrition Authors: Christina M. Hochkogler, Kathrin Liszt, Barbara Lieder, Verena St öger, Anna Stübler, Marc Pignitter, Joachim Hans, Sabine Widder, Jakob P. Ley, Gerhard E. Krammer, Veronika Somoza Tags: Research Article Source Type: research
miRNAs in nutrition, obesity, and cancer: The biology of miRNAs in metabolic disorders and its relationship with cancer development
ConclusionIn this review, we show how miRNAs are implicated in several signaling pathways as well as illustrating some bioactive compounds that impact inflammation and cancer development.
Epigenetics plays a main role in the metabolism and nutrition modulation as well as in the regulating pathways involved in the obesity establishment. Now, it is well established that obesity and cancer have a close association through microRNAs since these regulators could respond to metabolic and nutrition stimuli and induce relevant changes in the tumoral microenvironment. This review takes in perspective several mechanisms and cellula...
Source: Nahrung / Food - July 31, 2017 Category: Nutrition Authors: Ver ónica del Carmen Martínez‐Jiménez, Alejandro Méndez‐Mancilla, Diana Patricia Portales‐Pérez Tags: Review Source Type: research
Genistein and enterolactone in relation to Ki ‐67 expression and HER2 status in postmenopausal breast cancer patients
ConclusionOur findings indicate an inverse association between GEN and Ki‐67 at high levels of Ki‐67 expression. Additional investigations are recommended to confirm our findings and to further elucidate mechanisms linking PE metabolites to breast cancer survival.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 21, 2017 Category: Nutrition Authors: Stefanie Jaskulski, Audrey Y. Jung, Anja Rudolph, Theron Johnson, Kathrin Th öne, Esther Herpel, Peter Sinn, Jenny Chang‐Claude Tags: Research Article Source Type: research
Evaluation of the hypocholesterolemic effect and prebiotic activity of a lentil (Lens culinaris Medik) extract
Conclusion: This new hydroalcoholic extract obtained from lentils was shown to possess hypocholesterolemic and prebiotic properties, and could have interesting applications in the field of nutraceuticals.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 21, 2017 Category: Nutrition Authors: Maria Vittoria Micioni Di Bonaventura, Cinzia Cecchini, Pilar Vila Donat, Giovanni Caprioli, Carlo Cifani, Maria Magdalena Coman, Alberto Cresci, Dennis Fiorini, Massimo Ricciutelli, Stefania Silvi, Sauro Vittori, Gianni Sagratini Tags: Food & Function Source Type: research
Immunomodulatory properties of Olea europaea leaf extract in intestinal inflammation
Conclusion: Olive leaf extract presented intestinal anti‐inflammatory activity in colitis mouse models, maybe be related to its immunomodulatory properties and the capacity to restore the intestinal epithelial barrier. Besides, the extract could also regulate the activity of cells involved in the inflammatory response.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 21, 2017 Category: Nutrition Authors: Teresa Vezza, Francesca Algieri, Alba Rodr íguez‐Nogales, José Garrido‐Mesa, M Pilar Utrilla, Nassima Talhaoui, Ana María Gómez‐Caravaca, Antonio Segura‐Carretero, M Elena Rodríguez‐Cabezas, Giovanni Monteleone, Julio Gálvez Tags: Food & Function Source Type: research
Effects of Lysine deficiency and Lys ‐Lys dipeptide on cellular apoptosis and amino acids metabolism
ConclusionsAltogether, these studies suggest that Lys deficiency impairs AA metabolism and causes apoptosis. Lys‐Lys dipeptide serves as a Lys source and alleviates Lys deficiency induced cellular imbalance.
Lysine is a common limiting amino acid and there is a potential risk of lysine deficiency existing in developing countries, which may cause various physical problems, such as immune suppression, lower growth performance, cell arrest, and metabolic imbalance. The results show that lysine deficiency impairs amino acid metabolism and causes apoptosis in IPEC‐J2 cells and mice. Lys‐Lys dipeptide serves as a lysine s...
Source: Nahrung / Food - July 20, 2017 Category: Nutrition Authors: Jie Yin, Yuying Li, Hui Han, Jie Zheng, Lijian Wang, Wenkai Ren, Shuai Chen, Fei Wu, Rejun Fang, Xingguo Huang, Chunyong Li, Bie Tan, Xia Xiong, Yuzhe Zhang, Gang Liu, Jiming Yao, Tiejun Li, Yulong Yin Tags: Research Article Source Type: research
Metabolomic ‐based identification of clusters that reflect dietary patterns
ConclusionThe model developed was capable of classifying individuals into dietary patterns based on metabolomics data. Future applications of this approach could be developed for rapid and objective assignment of subjects into dietary patterns.
The identification of dietary patterns generally relies on self‐reporting dietary data which are prone to error. Using urinary metabolomics data, an objective dietary pattern classification model was developed. Two distinct dietary pattern clusters were identified, cluster one representing a healthy dietary pattern and cluster two representing an unhealthy dietary pattern. (Source: Nahrung / Food)
Source: Nahrung / Food - July 20, 2017 Category: Nutrition Authors: Helena Gibbons, Eibhlin Carr, Breige A. McNulty, Anne P. Nugent, Janette Walton, Albert Flynn, Michael J. Gibney, Lorraine Brennan Tags: Research Article Source Type: research
Phenol ‐enriched olive oils modify paraoxonase‐related variables: A randomized, crossover, controlled trial
ConclusionThis study reveals that the intake of phenol‐enriched FVOOs modulates oxidative balance by modifying PON‐related variables according to PC content and source, and this modulation can be perceived as beneficial.
Two randomized, controlled, double‐blind, and crossover interventions were conducted: Acute study: intake of functional virgin olive oils (FVOO) differing in phenolic compounds (PC) content; Sustained study: intake of different FVOOs (same PC content but different source). Main outcomes include that the acute and sustained consumption of olive oil‐PC in humans modifies PON‐related variables towa...
Source: Nahrung / Food - July 20, 2017 Category: Nutrition Authors: Sara Fern ández‐Castillejo, Ana‐Isabel García‐Heredia, Rosa Solà, Jordi Camps, Maria‐Carmen López de la Hazas, Marta Farràs, Anna Pedret, Úrsula Catalán, Laura Rubió, Maria‐José Motilva, Olga Castañer, María‐Isabel Covas, Rosa‐Mar Tags: Research Article Source Type: research
Assessing neurodevelopmental effects of arsenolipids in pre ‐differentiated human neurons
Conclusion: These results indicate for a neurodevelopmental potential of AsHCs. Taken into account the possibility that AsHCs might easily reach the developing brain when exposed during early life, neurotoxicity and neurodevelopmental toxicity cannot be excluded. Further studies are needed in order to progress the urgently needed risk assessment.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 20, 2017 Category: Nutrition Authors: Barbara Witt, Franziska Ebert, S ören Meyer, Kevin A. Francesconi, Tanja Schwerdtle Tags: Research Article Source Type: research
A novel neurological function of rice bran: a standardized rice bran supplement promotes non ‐rapid eye movement sleep in mice through histamine H1 receptors
Conclusions: RBS decreases sleep latency and promotes NREMS through the inhibition of H1R, suggesting that it could be a promising therapeutic agent for insomnia.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 19, 2017 Category: Nutrition Authors: Min Young Um, Sojin Kim, Young ‐Ho Jin, Minseok Yoon, Hyejin Yang, Jaekwang Lee, Jonghoon Jung, Yoshihiro Urade, Zhi‐Li Huang, Sangoh Kwon, Suengmok Cho Tags: Research Article Source Type: research
Adaptation of gut microbiome to different dietary nonstarch polysaccharide fractions in a porcine model
ConclusionThis study not only indicated how the gut microbiome adapts to the three major NSP fractions, but the results also contribute to our understanding of the role of dietary fibers in modulating gut microbiota and health.
Cecal digesta contain higher bacterial diversity than ileal digesta. Dietary fibers have no significant influence on overall diversity, but acutely alter the abundance of specific bacterial. Interestingly, ingestion of dietary fibers decreases the abundance of Firmicutes, but increases the abundance of Proteobacteria in ileal samples. (Source: Nahrung / Food)
Source: Nahrung / Food - July 18, 2017 Category: Nutrition Authors: Gang Tian, Xiying Wu, Daiwen Chen, Bing Yu, Jun He Tags: Research Article Source Type: research
Bioaccessibility, bioavailability and anti ‐inflammatory effects of anthocyanins from purple root vegetables using mono‐ and co‐culture cell models
ConclusionAnthocyanins from purple carrots and potatoes possess a promising anti‐inflammatory effect in model gut system. They can be absorbed and act differently but are in general beneficial for inflammation‐mediated diseases.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 10, 2017 Category: Nutrition Authors: Hua Zhang, Hassan Yousef, Justin Renaud, Ronghua Liu, Cheng Yang, Yong Sun, Rong Tsao Tags: Research Article Source Type: research
