Polyphenols from Lonicera caerulea L. berry attenuate experimental nonalcoholic steatohepatitis by inhibiting proinflammatory cytokines productions and lipid peroxidation
Conclusion: Dietary supplementation of LCP ameliorated inflammation and lipid peroxidation by up‐regulating Nrf2 and MnSOD, and down‐regulating FoxO1 and HO‐1 in NASH.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 8, 2016 Category: Nutrition Authors: Shusong Wu, Satoshi Yano, Ayami Hisanaga, Xi He, Jianhua He, Kozue Sakao, De ‐Xing Hou Tags: Food & Function Source Type: research

Stabilized sulforaphane for clinical use: phytochemical delivery efficiency
Conclusion: Our studies of a stabilized phytochemical component of foods should encourage further examination of similar products for their utility in chronic disease prevention and therapy.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 8, 2016 Category: Nutrition Authors: Jed W. Fahey, Kristina L. Wade, Scott L. Wehage, W. David Holtzclaw, Hua Liu, Paul Talalay, Edward Fuchs, Katherine K. Stephenson Tags: Research Article Source Type: research

APOLIPOPROTEIN E (epsilon) genotype has a greater impact on apoB ‐48 than apoB‐100 responses to dietary fat manipulation– insights from the SATgenε study
ConclusionOur study revealed marked effects of dietary fat composition on the Sf>400 apoB‐48 response and particle TAG content in E4 carriers relative to the ‘wild‐type’ E3/E3 genotype, which suggest APOE genotype is a potential modulator of chylomicron particle synthesis.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 8, 2016 Category: Nutrition Authors: Kim G Jackson, Stacey Lockyer, Andrew L Carvalho ‐Wells, Christine M Williams, Anne M Minihane, Julie A Lovegrove Tags: Food & Function Source Type: research

Alleviating VLDL overproduction is an important mechanism for Laminaria japonica polysaccharide to inhibit atherosclerosis in LDLr −/− mice with diet‐induced insulin resistance
Conclusion: These results suggested that LJP61A ameliorated HFD‐induced insulin resistance to attenuate VLDL overproduction possibly via regulating insulin signaling, leading to the inhibition of atherosclerosis.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 7, 2016 Category: Nutrition Authors: Xue ‐Qiang Zha, Wei‐Nan Zhang, Fu‐Hua Peng, Lei Xue, Jian Liu, Jian‐Ping Luo Tags: Research Article Source Type: research

Maternal folate depletion during early development and high fat feeding from weaning elicit similar changes in gene expression, but not in DNA methylation, in adult offspring
Conclusion: Our observations align with, and provide evidence in support of, a potential underlying mechanism for, the ‘Predictive Adaptive Response’ hypothesis.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 7, 2016 Category: Nutrition Authors: Jill A. McKay, Long Xie, Michiel Adriaens, Chris T. Evelo, Dianne Ford, John C. Mathers Tags: Research Article Source Type: research

The BASALIT multicenter trial: Gly m 4 quantification for consistency control of challenge meal batches and toward Gly m 4 threshold data
ConclusionThe novel Gly m 4 specific ELISA proved consistency of challenge meal batches over a 56‐month study period. With an average of 178 μg/g Gly m 4 in SPI, Gly m 4 lowest observed adverse effect level can be calculated once clinical lowest observed adverse effect level data based on SPI are available. Hence, sensitivity of patients can be correlated to the relevant allergen content instead of total protein of the allergenic source. For soy food challenge of patients with birch‐associated and Gly m 4 allergen mediated soy allergy, consistently stable Gly m 4 levels were required in standardized challenge m...
Source: Nahrung / Food - December 4, 2016 Category: Nutrition Authors: Thomas Holzhauser, Annegret Franke, Regina Treudler, Anett Schmiedeknecht, Stefanie Randow, Wolf ‐Meinhard Becker, Jonas Lidholm, Stefan Vieths, Jan‐Christoph Simon Tags: Research Article Source Type: research

Zinc ‐rich oysters as well as zinc yeast‐ and astaxanthin‐enriched food improved sleep efficiency and sleep onset in a randomized controlled trial of healthy individuals
ConclusionActigraphic sleep monitoring demonstrated that eating zinc‐rich food improved sleep onset latency as well as improved the sleep efficiency in healthy individuals.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - November 30, 2016 Category: Nutrition Authors: Hitomi Saito, Yoan Cherasse, Rina Suzuki, Makoto Mitarai, Fumitaka Ueda, Yoshihiro Urade Tags: Research Article Source Type: research

Whey protein isolate improves vitamin B12 and folate status in elderly Australians with sub ‐clinical deficiency of vitamin B12
Conclusion: Results indicate that WPI consumption improves active B12 and folate status. Unlike SPI, WPI consumption may prevent increase in MMA, HCY and genome instability in older Australians with low vitamin B12 status.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - November 30, 2016 Category: Nutrition Authors: Varinderpal S. Dhillon, Dimitrios Zabaras, Theodora Almond, Paul Cavuoto, Genevieve James ‐Martin, Michael Fenech Tags: Research Article Source Type: research

Resveratrol attenuates mitochondrial dysfunction in the liver of intrauterine growth retarded suckling piglets by improving mitochondrial biogenesis and redox status
Conclusion: RSV may have beneficial effects in improving hepatic mitochondrial function and redox status in the IUGR piglets.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - November 30, 2016 Category: Nutrition Authors: Hao Zhang, Yue Li, Weipeng Su, Zhixiong Ying, Le Zhou, Lili Zhang, Tian Wang Tags: Research Article Source Type: research

A comprehensive meta ‐analysis on dietary flavonoid and lignan intake and cancer risk: level of evidence and limitations
Conclusions: Most evidence reported in previous meta‐analyses was driven by case‐control studies. Overall results may be promising but are inconclusive. Further prospective cohorts assessing dietary polyphenol exposure and studies using other methods to evaluate exposure (i.e. markers of consumption, metabolism, excretion) are needed to confirm and determine consumption levels required to achieve health benefits.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - November 30, 2016 Category: Nutrition Authors: Giuseppe Grosso, Justyna Godos, Rosa Lamuela ‐Raventos, Sumantra Ray, Agnieszka Micek, Andrzej Pajak, Salvatore Sciacca, Nicolantonio D'Orazio, Daniele Del Rio, Fabio Galvano Tags: Research Article Source Type: research

The influence of a chronic L ‐carnitine administration on the plasma metabolome of male Fischer 344 rats
ConclusionAlthough L‐carnitine supplementation did not cause large changes in the plasma metabolome, a higher risk for cardiovascular disease due to chronically elevated TMAO plasma concentrations cannot be excluded.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - November 30, 2016 Category: Nutrition Authors: Christoph H. Weinert, Michael T. Empl, Ralf Kr üger, Lara Frommherz, Björn Egert, Pablo Steinberg, Sabine E. Kulling Tags: Research Article Source Type: research

Addressing the inter ‐individual variation in response to consumption of plant food bioactives: Towards a better understanding of their role in healthy aging and cardiometabolic risk reduction
Bioactive compounds in plant‐based foods have health properties that contribute to the prevention of age‐related chronic diseases, particularly cardiometabolic disorders. Conclusive proof and understanding of these benefits in humans is essential in order to provide effective dietary recommendations but, so far, the evidence obtained from human intervention trials is limited and contradictory. This is partly due to differences between individuals in the absorption, distribution, metabolism and excretion of bioactive compounds, as well as to heterogeneity in their biological response regarding cardiometabolic health out...
Source: Nahrung / Food - November 14, 2016 Category: Nutrition Authors: Claudine Manach, Dragan Milenkovic, Tom de Wiele, Ana Rodriguez ‐Mateos, Baukje Roos, Maria Teresa Garcia‐Conesa, Rikard Landberg, Eileen R. Gibney, Marina Heinonen, Francisco Tomás‐Barberán, Christine Morand Tags: Review Source Type: research

Canthaxanthin: From molecule to function
The aim of this review is to summarize the relevant literature about the use of canthaxanthin in food science and nutrition research. Canthaxanthin is a red‐orange carotenoid that belongs to the xanthophyll group. This naturally occurring pigment is present in bacteria, algae and some fungi. Canthaxanthin is also responsible for the color of flamingo feathers, koi carp skin and crustacean shells. Canthaxanthin is widely used in poultry (broiler, laying hens) as a feed additive. Canthaxanthin can be obtained by total synthesis. The canthaxanthin‐mediated color of foods is an important quality criterion for consumers. Re...
Source: Nahrung / Food - November 14, 2016 Category: Nutrition Authors: Tuba Esatbeyoglu, Gerald Rimbach Tags: Review Source Type: research

Sesamol supplementation prevents systemic inflammation ‐induced memory impairment, amyloidogenesis via inhibition of nuclear factor kappaB
Conclusion: These results indicated that sesamol mitigated LPS‐induced amyloidogenesis and memory impairment via inhibiting NFκB signal pathway, suggesting that the compound might be plausible therapeutic intervention for neuroinflammation‐related diseases such as AD.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - November 14, 2016 Category: Nutrition Authors: Zhigang Liu, Yuwei Chen, Qinglian Qiao, Yali Sun, Qian Liu, Bo Ren, Xuebo Liu Tags: Research Article Source Type: research

Prospective study of the dietary inflammatory index and risk of breast cancer in postmenopausal women
ConclusionA pro‐inflammatory diet, as indicated by higher DII scores, appears to increase the risk of developing breast cancer, especially in obese postmenopausal women.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - November 9, 2016 Category: Nutrition Authors: Nitin Shivappa, Cindy K. Blair, Anna E Prizment, David R. Jacobs, James R. H ébert Tags: Research Article Source Type: research