Zinc ‐rich oysters as well as zinc‐yeast‐ and astaxanthin‐enriched food improved sleep efficiency and sleep onset in a randomized controlled trial of healthy individuals
ConclusionActigraphic sleep monitoring demonstrated that eating zinc‐rich food improved sleep onset latency as well as improved the sleep efficiency in healthy individuals.
We conducted a randomized, double‐blinded, placebo‐controlled parallel group trial of 120 healthy subjects and actigraphically recorded their night activity for 12 weeks. Subjects were divided into four groups: placebo; zinc‐rich food; zinc‐ and astaxanthin‐rich food; placebo supplemented with zinc‐enriched yeast and astaxanthin oil. We demonstrated that eating zinc‐rich food improved sleep onset latency as well as improved the sleep ef...
Source: Nahrung / Food - February 26, 2017 Category: Nutrition Authors: Hitomi Saito, Yoan Cherasse, Rina Suzuki, Makoto Mitarai, Fumitaka Ueda, Yoshihiro Urade Tags: Research Article Source Type: research
Anti ‐diabetic activities of cis‐ and trans‐2,3,5,4′‐tetrahydroxystilbene 2‐O‐β‐glucopyranoside from Polygonum multiflorum
Conclusion: Cis‐THSG can be an enriched bioactive ingredient in PM roots from post‐processing and is significantly more effective against hyperglycemia than trans‐THSG. One of the effective pathways was through inhibition of PEPCK.
Trans‐2,3,5,4′‐tetrahydroxystilbene 2‐O‐β‐glucopyranoside (trans‐THSG) is the major active compound in a medicinal food in Asia, Polygonum multiflorum (PM), and it can be induced through UV light to cis‐THSG, which mimics the traditional process of PM. Cis‐THSG can be an enriched bioactive ingredient in PM roots from post‐processing after PM harvesting and is signific...
Source: Nahrung / Food - February 23, 2017 Category: Nutrition Authors: Wenping Tang, Shiming Li, Yue Liu, Jia ‐Ching Wu, Min‐Hsiung Pan, Mou‐Tuan Huang, Chi‐Tang Ho Tags: Research Article Source Type: research
High fat diet and associated changes in the expression of micro ‐RNAs in tissue: lessons learned from animal studies
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Source: Nahrung / Food - February 23, 2017 Category: Nutrition Authors: Robin A. Wilson, William Deasy, Alan Hayes, Matthew B. Cooke Tags: Review Source Type: research
Treatment with alpha ‐galactosylceramide protects mice from early onset of nonalcoholic steatohepatitis: Role of intestinal barrier function
ConclusionTaken together, our data suggest that the protective effects of αGalCer against the development of a diet‐induced NASH in mice are associated with a protection against the increased translocation of intestinal bacterial endotoxins associated with the development of NASH.
Chronic intake of a Western‐style diet leads to impairments of intestinal barrier function and increased translocation of bacterial endotoxins and subsequently resulting in the development of liver steatosis and inflammation. The protective effects of alpha‐galactosylceramide against the onset of Western‐style diet‐induced nonalcoholi...
Source: Nahrung / Food - February 21, 2017 Category: Nutrition Authors: Anna Janina Engstler, Cathrin Sellmann, Cheng Jun Jin, Annette Brandt, Kathleen Herz, Josephine Priebs, Ina Bergheim Tags: Research Article Source Type: research
Chronic supplementation with dietary proanthocyanidins protects from diet ‐induced intestinal alterations in obese rats
Conclusion: This study provides evidence for the ameliorative effect of a proanthocyanidin extract on high‐fat/high‐carbohydrate diet‐induced intestinal alterations, specifically reducing intestinal inflammation and oxidative stress and suggesting a protection against a barrier defect.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 19, 2017 Category: Nutrition Authors: Gil ‐Cardoso Katherine, Ginés Iris, Pinent Montserrat, Ardévol Anna, Arola Lluís, Blay Mayte, Terra Ximena Tags: Research Article Source Type: research
The effects of exogenous fatty acids and niacin on human monocyte ‐macrophage plasticity
Conclusion: Our study underlines a role of postprandial TRLs as a metabolic entity in regulating the plasticity of the monocyte‐macrophage lineage and also brings an understanding of the mechanisms by which dietary fatty acids are environmental factors fostering the innate immune responsiveness in humans.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 19, 2017 Category: Nutrition Authors: Sergio Montserrat ‐de la Paz, Dolores Rodriguez, Magdalena P. Cardelo, Maria C. Naranjo, Beatriz Bermudez, Rocio Abia, Francisco J.G. Muriana, Sergio Lopez Tags: Research Article Source Type: research
Specific inulin ‐type fructan fibers protect against autoimmune diabetes by modulating gut immunity, barrier function and microbiota homeostasis
Conclusion: Our data demonstrate that ITF(l) but not ITF(s) delays the development of T1D via modulation of gut‐pancreatic immunity, barrier function and microbiota homeostasis.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - February 19, 2017 Category: Nutrition Authors: Kang Chen, Hao Chen, Marijke M. Faas, Bart J. Haan, Jiahong Li, Ping Xiao, Hao Zhang, Julien Diana, Paul Vos, Jia Sun Tags: Research Article Source Type: research
Whey protein isolate improves vitamin B12 and folate status in elderly Australians with subclinical deficiency of vitamin B12
ConclusionResults indicate that WPI consumption improves active B12 and folate status. Unlike SPI, WPI consumption may prevent increase in MMA, HCY, and genome instability in older Australians with low vitamin B12 status.
Problems associated with low appetite, nutrient absorption, transport, and metabolism are common among older people leading to deficiency of vitamin B12 and folate (vitamin B9). Whey protein isolate (WPI) contains substantial amounts of vitamin B12 and folate but bioavailability of these vitamins from WPI is not known. The effects of WPI on B12 and folate status were tested in a double‐blind, cross‐o...
Source: Nahrung / Food - February 8, 2017 Category: Nutrition Authors: Varinderpal S. Dhillon, Dimitrios Zabaras, Theodora Almond, Paul Cavuoto, Genevieve James ‐Martin, Michael Fenech Tags: Research Article Source Type: research
Sesamol ameliorates diet ‐induced obesity in C57BL/6J mice and suppresses adipogenesis in 3T3‐L1 cells via regulating mitochondria‐lipid metabolism
ConclusionTaken together, this study provides compelling evidence that sesamol supplementation reduced adipocyte size and adipogenesis of diet‐induced obesity by regulating mitochondria lipid metabolism.
Supplementation of sesamol, a nature phenol derivative of sesame oil, suppresses obesity and insulin resistance in high‐fat and high‐fructose diet fed mice. Sesamol downregulates lipogenesis in liver, inhibits lipid accumulation and inflammatory responses in white adipose tissue, and decrease adipocytes sizes and “whitening” of brown adipose tissues via improving mitochondria lipid metabolism. (Source: Nahrung / Food)
Source: Nahrung / Food - February 6, 2017 Category: Nutrition Authors: Zhigang Liu, Qinglian Qiao, Yali Sun, Yuwei Chen, Bo Ren, Xuebo Liu Tags: Research Article Source Type: research
Absorption, distribution, metabolism, and excretion of [14C]sesamin in rats
ConclusionsSesamin was absorbed efficiently and distributed over the whole body. In particular, sesamin was highly distributed in the form of the metabolites in the liver and kidney. The results of this study are useful in elucidating the action mechanism of sesamin.
Sesamin is a major lignan in sesame seeds and has various physiological effects. Sesamin is absorbed efficiently and distributed over the whole body. In particular, sesamin is highly distributed in the form of its metabolites in the liver and kidney. The various physiological effects of sesamin may be due to the action of its metabolites. (Source: Nahrung / Food)
Source: Nahrung / Food - February 5, 2017 Category: Nutrition Authors: Namino Tomimori, Tomohiro Rogi, Hiroshi Shibata Tags: Research Article Source Type: research
The common dietary flavonoid myricetin attenuates liver fibrosis in carbon tetrachloride treated mice
ConclusionMyricetin inhibits the activation of HSCs and ameliorates CCl4‐induced liver fibrosis in mice and may serve as a potential therapeutic agent in the treatment of liver fibrosis.
Myricetin, a natural flavonoid found in berries, vegetables, and herbs, has unique biological activities. Here, it is reported that myricetin inhibits proliferation, migration, and extracellular matrix (ECM) accumulation of activated HSCs stimulated by TGF‐β1 or PDGF in HSCs and reduces the degree of liver fibrosis induced by CCl4 in mice. The mechanism by which it inhibits liver fibrosis is blocking phosphorylation of Smad2/Akt/MAPK...
Source: Nahrung / Food - February 5, 2017 Category: Nutrition Authors: Yan Geng, Qing Sun, Wang Li, Zhen ‐Ming Lu, Hong‐Yu Xu, Jin‐Song Shi, Zheng‐Hong Xu Tags: Research Article Source Type: research
Boswellia serrata resin extract alleviates azoxymethane (AOM)/dextran sodium sulfate (DSS) ‐induced colon tumorigenesis
ConclusionIn summary, BS extract decreased the protein levels of inflammative enzymes such as iNOS and COX‐2 in colonic mucosa. It also mediated Akt/GSK3β/cyclin D1 signaling pathway and altered the composition of gut microbiota to alleviate tumor growth. Taken together, this study suggests that BS extract has great potential to suppress colon tumorigenesis.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - January 31, 2017 Category: Nutrition Authors: Ya ‐Chun Chou, Joon Hyuk Suh, Yu Wang, Manoj Pahwa, Vladimir Badmeav, Chi‐Tang Ho, Min‐Hsiung Pan Tags: Food & Function Source Type: research
Phytochemicals in quinoa and amaranth grains and their antioxidant, anti ‐inflammatory and potential health beneficial effects: a review
This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - January 31, 2017 Category: Nutrition Authors: Yao Tang, Rong Tsao Tags: Review Source Type: research
Physiologically based kinetic modeling of hesperidin metabolism and its use to predict in vivo effective doses in humans
ConclusionsThe developed PBK model adequately predicts ADME of hesperidin in humans, and allows to evaluate the human in vivo situation without the need for human intervention studies.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - January 31, 2017 Category: Nutrition Authors: Rungnapa Boonpawa, Albertus Spenkelink, Ans Punt, Ivonne M. C. M. Rietjens Tags: Research Article Source Type: research
The phenolic fraction of extra virgin olive oil modulates the activation and the inflammatory response of T cells from patients with systemic lupus erythematosus and healthy donors
Conclusion: PE modulates cytokine production and attenuates induced T cell activation, probably through nuclear factor (NF‐κB) signaling pathway, providing the first evidence that PE from EVOO has an anti‐inflammatory and immunomodulatory role in SLE patients and it might therefore be considered as a dietary complement in SLE managementThis article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - January 31, 2017 Category: Nutrition Authors: Marina Aparicio ‐Soto, Marina Sanchez‐Hidalgo, Ana Cárdeno Galván, Jose Manuel Lucena, Francisca Gonzalez‐Escribano, Maria Jesus Castillo Palma, Catalina Alarcón‐de‐la‐Lastra Tags: Research Article Source Type: research
