Whey protein isolate improves vitamin B12 and folate status in elderly Australians with subclinical deficiency of vitamin B12

ConclusionResults indicate that WPI consumption improves active B12 and folate status. Unlike SPI, WPI consumption may prevent increase in MMA, HCY, and genome instability in older Australians with low vitamin B12 status. Problems associated with low appetite, nutrient absorption, transport, and metabolism are common among older people leading to deficiency of vitamin B12 and folate (vitamin B9). Whey protein isolate (WPI) contains substantial amounts of vitamin B12 and folate but bioavailability of these vitamins from WPI is not known. The effects of WPI on B12 and folate status were tested in a double‐blind, cross‐over intervention in elderly Australians with subclinical deficiency in vitamin B12 and compared to soy protein isolate (SPI) that lacks vitamin B12 and folate. The results suggest that WPI consumption improves active B12 as well as folate status and may prevent increase in methylmalonic acid (MMA), homocysteine (HCY), and genome instability in older Australians with subclinical deficiency of vitamin B12.
Source: Nahrung / Food - Category: Nutrition Authors: Tags: Research Article Source Type: research