Front cover: Exacerbation of liver steatosis following exposure to famine and overnutrition
Mol. Nutr. Food Res. 2017, 61, 1700097.
DOI: 10.1002/mnfr.201700097
Food restriction in early life, the first hit, leads to increased gluconeogenesis and decreased muscle glucose uptake. This may induce elevated glucose flux into the liver and liver fatty acid synthetase expression, which further leads to enhanced de novo lipogenesis and steatosis. Furthermore, overnutrition, the second hit in later life, exacerbates liver steatosis. (Source: Nahrung / Food)
Source: Nahrung / Food - October 5, 2017 Category: Nutrition Authors: Zhiyuan Ning, Kun Zhang, Li Zhao, You Lu, Honglin Sun, Chi Chen, Xiaomin Nie, Meng Lu, Ningjian Wang, Yingli Lu Tags: Front Cover Source Type: research
Early Supplementation of D ‐cysteine or L‐Cysteine Prevents Hypertension and Kidney Damage in Spontaneously Hypertensive Rats Exposed to High‐Salt Intake
Conclusion: Early supplementation of D‐ or L‐cysteine before hypertension becomes evident may protect against hypertension and kidney damage in adult SHRs exposed to high salt consumption via regulation of oxidative stress, renin‐angiotensin system, and H2S‐generating pathways.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 5, 2017 Category: Nutrition Authors: Chien ‐Ning Hsu, Yu‐Ju Lin, Pei‐Chen Lu, You‐Lin Tain Tags: RESEARCH ARTICLE Source Type: research
Ser71 of αS1‐Casein is Phosphorylated in Breast Milk—Evidence from Targeted Mass Analysis
ConclusionPhospho‐occupancy rates varied greatly and could not be confidently correlated to other parameters within the cohort of 20 donors. The new phosphosite S71 is located in the neighborhood of the serine‐rich region and may contribute to the cluster of high charge density at normal milk pH, likely exerting an influence on protein tertiary structure and thus function.
αS1‐casein phosphorylation at S71 is detected in breast milk by tandem mass spectrometry. The site is located in a sequences region different from that in other mammalian species but close to the conserved phosphoserine‐rich region. Phosphoryla...
Source: Nahrung / Food - October 4, 2017 Category: Nutrition Authors: Simone K önig, Irina Altendorfer, Thorsten Saenger, Ellen Bleck, Stefan Vordenbäumen, Matthias Schneider, Joachim Jose Tags: RESEARCH ARTICLE Source Type: research
A 48 ‐Hour Vegan Diet Challenge in Healthy Women and Men Induces a BRANCH‐Chain Amino Acid Related, Health Associated, Metabolic Signature
Conclusions: The vegan diet lowered triglycerides, insulin and homeostatic model assessment (HOMA‐IR), bile acids, elevated magnesium levels, and changed branched‐chain amino acids (BCAAs) metabolism (p<0.05), potentiating insulin and blood sugar control after 48 hours. Cholesterol control improved significantly in the vegan verses omnivorous diets. Plasma amino acid and magnesium concentrations positively correlated with dietary amino acids. Polyunsaturated fatty acids and dietary fiber inversely correlated with insulin, HOMA‐IR and triglycerides. Nutritional biochemistries, BCAAs, insulin and HOMA‐IR were impa...
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Colleen Fogarty Draper, Irene Vassallo, Alessandro Di Cara, Cristiana Milone, Ornella Comminetti, Irina Monnard, Jean ‐Philippe Godin, Max Scherer, MingMing Su, Wei Jia, Seu‐Ping Guiraud, Fabienne Praplan, Laurence Guignard, Corinne Ammon Zufferey, Ma Tags: RESEARCH ARTICLE Source Type: research
Flavonoid ‐Rich Apple Improves Endothelial Function in Individuals at Risk for Cardiovascular Disease: A Randomised Controlled Clinical Trial
Conclusion: A lower risk of CVD with higher apple consumption could be mediated by the beneficial effect of apple skin on endothelial function, both acutely and chronically.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Nicola P. Bondonno, Catherine P. Bondonno, Lauren C. Blekkenhorst, Michael J. Considine, Ghassan Maghzal, Roland Stocker, Richard J. Woodman, Natalie C. Ward, Jonathan M. Hodgson, Kevin D. Croft Tags: Research Article Source Type: research
Dietary Glycation Products Regulate Immune Homeostasis: Early Glycation Products Promote Prostate Cancer Cell Proliferation through Modulating Macrophages
Conclusions: Our data suggest that EGPs promote the prostate tumor proliferation indirectly through modulating macrophages, while AGEs have a direct effect.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Yingjia Chen, Nikolay M. Filipov, Tai L. Guo Tags: Research Article Source Type: research
Antidiabetic Activity of Ergosterol from Pleurotus Ostreatus in KK ‐Ay Mice with Spontaneous Type 2 Diabetes Mellitus
ConclusionThe results suggest that ERG may be a potential hypoglycemic agent for the treatment of T2DM with the probable mechanism of stimulating GLUT4 translocation and expression modulated by the PI3K/Akt pathway and PKC pathway.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Mingrui Xiong, Yun Huang, Yajing Liu, Mi Huang, Guanjun Song, Qian Ming, Xinhua Ma, Jie Yang, Shihao Deng, Yanzhang Wen, Jinhua Shen, Qing ‐Hua Liu, Ping Zhao, Xinzhou Yang Tags: RESEARCH ARTICLE Source Type: research
High Resolution Mass Spectrometric Analysis of Secoiridoids and Metabolites as Biomarkers of Acute Olive Oil Intake – an Approach to Study Inter‐Individual Variability in Humans
Conclusions: plasma (elenolic acid + H2; p‐HPEA‐EA + H2 + glucuronide) and urinary (3,4‐DHPEA‐EA, 3,4‐DHPEA‐EA + H2+glucuronide, methyl 3,4‐DHPEA‐EA + H2+glucuronide) secoiridoid compounds were selected as biomarkers to monitor EVOO intake showing good predictive ability according to multivariate analysis.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Sandra Silva, Mar Garcia ‐Aloy, Maria Eduardo Figueira, Emilie Combet, William Mullen, Maria Rosário Bronze Tags: RESEARCH ARTICLE Source Type: research
Ferric Citrate Supplementation Reduces Red Blood Cell Aggregation and Improves CD163+ Macrophage ‐Mediated Hemoglobin Metabolism in a Rat Model of High‐Fat‐Diet‐Induced Obesity
Conclusions: Ferric citrate supplementation reduces RBC aggregation and improves CD163+ macrophage‐mediated Hb metabolism in HFD‐induced obese rats. These findings suggest that ferric citrate may be explored as an alternative treatment method for RBC dysfunction.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Ting ‐Yun Chang, Kai‐Li Liu, Cheng Sheng Chang, Chien‐Tien Su, Seu‐Hwa Chen, Yu‐Chieh Lee, Jung‐Su Chang Tags: RESEARCH ARTICLE Source Type: research
Effects of Dairy Products Consumption on Body Weight and Body Composition Among Adults: An Updated Meta ‐Analysis of 37 Randomized Control Trials
Conclusions: This meta‐analysis suggests a beneficial effect of energy‐restricted dairy consumption on body weight and body composition. However, high dairy consumption in the absence of caloric restriction may increase body weight.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Tingting Geng, Lu Qi, Tao Huang Tags: RESEARCH ARTICLE Source Type: research
No Adverse Programming by Post ‐Weaning Dietary Fructose of Body Weight, Adiposity, Glucose Tolerance or Metabolic Flexibility
Conclusions: Our present findings indicate no adverse programming of body weight, adiposity, glucose tolerance and metabolic flexibility by dietary (solid) fructose in comparison to glucose in the post‐weaning diet in mice.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Lianne M. S. Bouwman, Jos é M. S. Fernández‐Calleja, Hans J. M. Swarts, Inge der Stelt, Annemarie Oosting, Jaap Keijer, Evert M. Schothorst Tags: RESEARCH ARTICLE Source Type: research
Blueberry Metabolites Attenuate Lipotoxicity ‐Induced Endothelial Dysfunction
Conclusion: Our findings indicate that the vascular benefits of blueberry anthocyanins are mediated by their metabolites. Blueberries might complement existing therapies to improve vascular complications.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Divya Bharat, Rafaela Ramos Mororo Cavalcanti, Chrissa Petersen, Nathan Begaye, Brett Ronald Cutler, Marcella Melo Assis Costa, Renata Kelly Luna Gomes Ramos, Marina Ramos Ferreira, Youyou Li, Leena P Bharath, Emma Toolson, Paul Sebahar, Ryan E Looper, Th Tags: RESEARCH ARTICLE Source Type: research
Excretion of Avenanthramides, Phenolic Acids and their Major Metabolites Following Intake of Oat Bran
ConclusionOat bran phenolics follow a relatively rapid urinary excretion, with 30 metabolites excreted within 8h of intake. These levels of excretion suggest that bound phenolics are, in part, rapidly released by the microbiota.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Manuel Y Schar, Giulia Corona, Gulten Soycan, Clemence Dine, Angelika Kristek, Sarah N S Alsharif, Volker Behrends, Alison Lovegrove, Peter R Shewry, Jeremy P E Spencer Tags: Research Article Source Type: research
Nutrikinetics of Isoflavone Metabolites After Fermented Soybean Product (Cheonggukjang) Ingestion in Ovariectomized Mice
ConclusionsCGJ has good isoflavone bioavailability and may be beneficial for the bone health of post‐menopausal women.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - October 1, 2017 Category: Nutrition Authors: Da ‐Hye Lee, Min Jung Kim, Jiyun Ahn, Sang Hee Lee, Hyunjung Lee, Jin Hee Kim, So‐Hyun Park, Young‐Jin Jang, Tae‐Youl Ha, Chang Hwa Jung Tags: Research Article Source Type: research
Weighted Gene Co ‐Expression Network Analysis Identifies Gender Specific Modules and Hub Genes Related to Metabolism and Inflammation in Response to an Acute Lipid Challenge
Conclusion: The OLTT induced some gender specific correlations of gene co‐expression network modules. In females, biological processes relating to energy metabolism and inflammation pathways were evident. This suggests a gender specific link between inflammation and energy metabolism in response to lipids. In contrast, G‐protein coupled receptor protein signalling pathway was common to both genders.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - September 26, 2017 Category: Nutrition Authors: Attia Fatima, Ruth M. Connaughton, Anna Weiser, Aoife M. Murphy, Colm O'Grada, Miriam Ryan, Lorraine Brennan, Peadar O'Gaora, Helen M. Roche Tags: Research Article Source Type: research
