Casein glycomacropeptide ‐derived peptide IPPKKNQDKTE ameliorates high glucose‐induced insulin resistance in HepG2 cells via activation of AMPK signaling
Conclusion: IPPKKNQDKTE prevents high glucose‐induced insulin resistance in HepG2 cells by modulating the IRS‐1/PI3K/Akt signaling pathway through AMPK activation, indicating that IPPKKNQDKTE plays a potential role in the prevention and treatment of hepatic insulin resistance and type 2 diabetes.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - August 8, 2016 Category: Nutrition Authors: Jia ‐jia Song, Qian Wang, Min Du, Tian‐ge Li, Bin Chen, Xue‐ying Mao Tags: Research Article Source Type: research
Food combination based on a pre ‐hispanic Mexican diet decreases metabolic and cognitive abnormalities and gut microbiota dysbiosis caused by a sucrose‐enriched high‐fat diet in rats
ConclusionConsumption of a PMD decreased the glucose intolerance and the biochemical abnormalities caused by the obesity by increasing the abundance of proteins involved in fatty acid oxidation, decreasing the oxidative stress and modifying the gut microbiota.
The effect of the consumption of a pre‐Hispanic Mexican diet (PMD) in rats fed a sucrose‐enriched high fat diet is discussed. The presence of soluble and insoluble fiber, antioxidants, polyunsaturated fatty acids and small amounts of docosahexaenoic acid and eicosapentaenoic acid from black beans, corn, tomato, nopal, chia and pumpkin seeds synergistically ameli...
Source: Nahrung / Food - August 7, 2016 Category: Nutrition Authors: Azalia Avila ‐Nava, Lilia G. Noriega, Armando R. Tovar, Omar Granados, Claudia Perez‐Cruz, José Pedraza‐Chaverri, Nimbe Torres Tags: Research Article Source Type: research
The ginger component 6 ‐shogaol prevents TNF‐α‐induced barrier loss via inhibition of PI3K/Akt and NF‐κB signaling
Conclusion: 6‐SG has barrier‐protective effects by affecting TNF‐α‐induced claudin‐2 upregulation and claudin‐1 disassembly via inhibition of PI3K/Akt and NF‐κB signaling. Therefore, 6‐SG‐containing food might be beneficial for barrier preservation during intestinal inflammation.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - August 3, 2016 Category: Nutrition Authors: Julia Luettig, Rita Rosenthal, In ‐Fah M. Lee, Susanne M. Krug, Jörg D. Schulzke Tags: Research Article Source Type: research
Genistein and delphinidin antagonize the genotoxic effects of the mycotoxin alternariol in human colon carcinoma cells
Conclusion: Our data indicate that a respective polyphenol‐rich diet might aid to protect against genotoxic damages caused by AOH, whereby bioactive concentrations of DEL are predominantly expected locally in the intestines.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 31, 2016 Category: Nutrition Authors: Georg Aichinger, Julia Beisl, Doris Marko Tags: Research Article Source Type: research
Rat health status affects bioavailability, target tissue levels, and bioactivity of grape seed flavanols
Conclusions: This study demonstrates important differences in bioactivity and target tissue metabolite levels between healthy and diseased rats, indicating potential metabolites responsible of the antihypertensive effect.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - July 31, 2016 Category: Nutrition Authors: Maria Margalef, Zara Pons, Lisard Iglesias ‐Carres, Mar Quiñones, Francisca Isabel Bravo, Anna Arola‐Arnal, Begoña Muguerza Tags: Research Article Source Type: research
