Casein glycomacropeptide ‐derived peptide IPPKKNQDKTE ameliorates high glucose‐induced insulin resistance in HepG2 cells via activation of AMPK signaling

Conclusion: IPPKKNQDKTE prevents high glucose‐induced insulin resistance in HepG2 cells by modulating the IRS‐1/PI3K/Akt signaling pathway through AMPK activation, indicating that IPPKKNQDKTE plays a potential role in the prevention and treatment of hepatic insulin resistance and type 2 diabetes.This article is protected by copyright. All rights reserved

Source: Nahrung / Food - August 8, 2016 Category: Nutrition Authors: Jia ‐jia Song, Qian Wang, Min Du, Tian‐ge Li, Bin Chen, Xue‐ying Mao Tags: Research Article Source Type: research