Anti ‐diabetic activities of cis‐ and trans‐2,3,5,4'‐tetrahydroxystilbene 2‐O‐β‐glucopyranoside from Polygonum multiflorum
Conclusion: Cis‐THSG can be an enriched bioactive ingredient in PM roots from post‐processing and is significantly more effective against hyperglycemia than trans‐THSG. One of the effective pathways was through inhibition of PEPCK.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 31, 2016 Category: Nutrition Authors: Wenping Tang, Shiming Li, Yue Liu, Jia ‐Ching Wu, Min‐Hsiung Pan, Mou‐Tuan Huang, Chi‐Tang Ho Tags: Research Article Source Type: research

Creatine and creatine forms intended for sports nutrition
This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 24, 2016 Category: Nutrition Authors: Susanne Andres, Rainer Ziegenhagen, Iris Trefflich, Sophie Pevny, Katharina Schultrich, Hans Braun, Wilhelm Sch änzer, Karen Ildico Hirsch‐Ernst, Bernd Schäfer, Alfonso Lampen Tags: Review Source Type: research

Targeting the epigenome: Screening bioactive compounds that regulate histone deacetylase activity
ConclusionThis study provided the first step in identifying multiple bioactive compound HDAC inhibitors. Taken together, this report sets the stage for future exploration of these bioactive compounds as epigenetic regulators to potentially ameliorate chronic disease.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 15, 2016 Category: Nutrition Authors: Luis D. Godoy, Julianna E. Lucas, Abigail J. Bender, Samantha S. Romanick, Bradley S. Ferguson Tags: Research Article Source Type: research

Maternal vitamin D status during pregnancy and risk of childhood asthma ༚a meta‐analysis of prospective studies
ConclusionThis dose–response meta‐analysis suggested a U‐shaped relationship between maternal blood 25(OH)D levels and risk of childhood asthma. Further studies are needed to confirm the association.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 15, 2016 Category: Nutrition Authors: Huihui Song, Lei Yang, Chongqi Jia Tags: Research Article Source Type: research

Chicoric acid attenuate a nonalcoholic steatohepatitis by inhibiting key regulators of lipid metabolism, fibrosis, oxidation and inflammation in mice with methionine and choline deficiency
ConclusionsCDE and chicoric acid may be effective in the treatment of NAFLD and NASH.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 15, 2016 Category: Nutrition Authors: Myungsuk Kim, GyHye Yoo, Ahmad Randy, Hyoung Seok Kim, Chu Won Nho Tags: Research Article Source Type: research

New insights into the antiangiogenic and proangiogenic properties of dietary polyphenols
This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 15, 2016 Category: Nutrition Authors: Carmen Diniz, Joanna Suliburska, Isabel M.P.L.V.O. Ferreira Tags: Review Source Type: research

Early induction of pyruvate dehydrogenase kinase 4 by retinoic acids in adipocytes
Conclusion: In this study, we showed that adipocyte PDK4 gene is a new target of the vitamin A‐derived RA and might participate to the reduced fatty acid efflux from the adipocyte, a step that plays an important role in the developpement of metabolic diseases.This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 15, 2016 Category: Nutrition Authors: Emilie Distel, Thomas Cadoudal, Martine Collinet, Edwards A. Park, Chantal Benelli, Sylvie Bortoli Tags: Research Article Source Type: research

An extra virgin olive oil rich diet intervention ameliorates the nonalcoholic steatohepatitis induced by a high ‐fat “Western‐type” diet in mice
ConclusionDietary EVOO could repair HFD‐induced hepatic damage, possibly via an anti‐inflammatory effect in adipose tissue and modifications in the liver lipid composition and signaling pathways. Dietary fat may be an important modifiable factor involved in nonalcoholic fatty liver disease. The protective effect of extra virgin olive oil (EVOO) in high‐fat diets on the inflammatory response and liver damage is evaluated in a nonalcoholic fatty liver disease mouse model. EVOO diets improve plasma lipid profile, plasma and fat inflammation; ameliorate liver damage; increase MUFAs liver levels; and modify liver protein...
Source: Nahrung / Food - December 12, 2016 Category: Nutrition Authors: Enrique Jurado ‐Ruiz, Lourdes M. Varela, Amparo Luque, Genoveva Berná, Gladys Cahuana, Enrique Martinez‐Force, Rocío Gallego‐Durán, Bernat Soria, Baukje Roos, Manuel Romero Gómez, Franz Martín Tags: Research Article Source Type: research

Offspring predisposition to obesity due to maternal ‐diet‐induced obesity in rats is preventable by dietary normalization before mating
ConclusionRemoval of CD in obese rats before gestation, although without complete reversion of body weight excess, may prevent the expected detrimental effects in offspring associated to an excess fat accumulation in adulthood and the related metabolic disturbances. Dietary normalization in rats made obese by cafeteria diet feeding for 1 month before gestation, even without a complete reversal in excess weight and adiposity, prevents the harmful effects on offspring associated with maternal obesity. (Source: Nahrung / Food)
Source: Nahrung / Food - December 12, 2016 Category: Nutrition Authors: Heriberto Castro, Catalina Amadora Pomar, Andreu Palou, Catalina Pic ó, Juana Sánchez Tags: Research Article Source Type: research

Modulation of iron transport, metabolism and reactive oxygen status by quercetin –iron complexes in vitro
ConclusionQuercetin, an exogenous iron chelator, is able to render the cell functionally iron‐deficient which not only provides a therapeutic platform for chelating excess free luminal iron but also may be of use in limiting processes such as cancer‐cell growth, inflammation and bacterial infections, which all require iron. Excess free‐iron is detrimental to health due to its ability to catalyse the formation of cytotoxic reactive oxygen species. Specifically it is implicated in inflammatory conditions, cancer growth and fuelling bacterial infections. Polyphenolic compounds within our diets demonstrate iron‐bindin...
Source: Nahrung / Food - December 12, 2016 Category: Nutrition Authors: Richard D. Horniblow, Daisy Henesy, Tariq H. Iqbal, Chris Tselepis Tags: Research Article Source Type: research

Microbial and endogenous metabolic conversions of rye phytochemicals
This article is protected by copyright. All rights reserved (Source: Nahrung / Food)
Source: Nahrung / Food - December 12, 2016 Category: Nutrition Authors: Ville M Koistinen, Kati Hanhineva Tags: Review Source Type: research

Contents: Mol. Nutr. Food Res. 12'16
(Source: Nahrung / Food)
Source: Nahrung / Food - December 8, 2016 Category: Nutrition Tags: Contents Source Type: research

Editorial Board: Mol. Nutr. Food Res. 12'16
(Source: Nahrung / Food)
Source: Nahrung / Food - December 8, 2016 Category: Nutrition Tags: Editorial Board Source Type: research

Back cover: Heat processing of peanut seed enhances the sensitization potential of the major peanut allergen Ara h 6
Mol. Nutr. Food Res. 2016, 60, 2722–2735. DOI: 10.1002/mnfr.201500923 Heating is essential to the sensitization potency of Ara h 6 in peanut seeds. In fact, immunogenicity is supported by different structures, modified and/or produced during food processing in interaction with other food constituents. Conversely, native Ara h 6 is not immunogenic but is the support of IgE binding and elicitation of the allergic reaction. (Source: Nahrung / Food)
Source: Nahrung / Food - December 8, 2016 Category: Nutrition Authors: Blanche Guillon, Herv é Bernard, Marie‐Françoise Drumare, Stéphane Hazebrouck, Karine Adel‐Patient Tags: Back Cover Source Type: research

Front cover: Hypoglycemic activity of the Baker's yeast β‐glucan in obese/type 2 diabetic mice and the underlying mechanism
Mol. Nutr. Food Res. 2016, 60, 2678–2690. DOI: 10.1002/mnfr.201600032 The yeast β‐glucan (BYGlc) orally given to diet‐induced obese/type 2 diabetic mice improves hepatic glucose‐lipid homeostasis. BYGlc decreases blood glucose through inhibiting intestine SGLT‐1 expression, and alters the gut microbiota by increasing Akkermansia population, which may be associated with reduced inflammation. (Source: Nahrung / Food)
Source: Nahrung / Food - December 8, 2016 Category: Nutrition Authors: Yan Cao, Siwei Zou, Hui Xu, Mengxia Li, Zan Tong, Min Xu, Xiaojuan Xu Tags: Front Cover Source Type: research