An extra virgin olive oil rich diet intervention ameliorates the nonalcoholic steatohepatitis induced by a high ‐fat “Western‐type” diet in mice

ConclusionDietary EVOO could repair HFD‐induced hepatic damage, possibly via an anti‐inflammatory effect in adipose tissue and modifications in the liver lipid composition and signaling pathways. Dietary fat may be an important modifiable factor involved in nonalcoholic fatty liver disease. The protective effect of extra virgin olive oil (EVOO) in high‐fat diets on the inflammatory response and liver damage is evaluated in a nonalcoholic fatty liver disease mouse model. EVOO diets improve plasma lipid profile, plasma and fat inflammation; ameliorate liver damage; increase MUFAs liver levels; and modify liver protein expression. Dietary EVOO could repair high‐fat diet induced hepatic damage via an anti‐inflammatory effect and changes in the liver lipid composition and signaling pathways.

http://onlinelibrary.wiley.com/resolve/doi?DOI=10.1002%2Fmnfr.201600549

Source: Nahrung / Food - December 12, 2016 Category: Nutrition Authors: Enrique Jurado ‐Ruiz, Lourdes M. Varela, Amparo Luque, Genoveva Berná, Gladys Cahuana, Enrique Martinez‐Force, Rocío Gallego‐Durán, Bernat Soria, Baukje Roos, Manuel Romero Gómez, Franz Martín Tags: Research Article Source Type: research