Boswellia serrata resin extract alleviates azoxymethane (AOM)/dextran sodium sulfate (DSS) ‐induced colon tumorigenesis

ConclusionIn summary, BS extract decreased the protein levels of inflammative enzymes such as iNOS and COX‐2 in colonic mucosa. It also mediated Akt/GSK3β/cyclin D1 signaling pathway and altered the composition of gut microbiota to alleviate tumor growth. Taken together, this study suggests that BS extract has great potential to suppress colon tumorigenesis.This article is protected by copyright. All rights reserved

Source: Nahrung / Food - January 31, 2017 Category: Nutrition Authors: Ya ‐Chun Chou, Joon Hyuk Suh, Yu Wang, Manoj Pahwa, Vladimir Badmeav, Chi‐Tang Ho, Min‐Hsiung Pan Tags: Food & Function Source Type: research