Recovery of cytomegalovirus DNA from newborn saliva samples by different methods
Cytomegalovirus (CMV) is the most common congenital infection [1,2] and a leading cause of childhood hearing loss, cognitive deficits and visual impairment [3,4]. Diagnosis of congenital CMV infection (cCMV) allows affected infants optimal monitoring and interventions [5 –8]. A definitive diagnosis of cCMV requires viral detection within the first 21 days of life because postnatal acquisition of CMV is common in early infancy and is associated with less morbidity. Large amounts of CMV are continuously shed in the saliva and urine of congenitally infected newborn s [9]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - May 5, 2018 Category: Virology Authors: Oran Goshen, David M. Goldfarb, Book Laura, Peter Tilley, Soren Gantt Source Type: research
Different meteorological parameters influence metapneumovirus and respiratory syncytial virus activity
The objective of this study was to evaluate the association between respiratory syncytial virus RSV and human metapneumovirus (hMPV) detection in the community and local meteorological conditions. RSV and hMPV are two common viral respiratory pathogens. Both viruses cause a wide range of illnesses, ranging from mild colds to bronchiolitis or pneumonia. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - May 5, 2018 Category: Virology Authors: Magali Darniot, C écile Pitoiset, Laurine Millière, Ludwig Serge Aho-Glélé, Emmanuel Florentin, Jean-Baptiste Bour, Catherine Manoha Source Type: research
Clinical and biological features of enteroviral meningitis among adults and children and factors associated with severity and length of stay
Epidemics of meningitis due to enterovirus species are commonly observed worldwide during the summer in temperate climates such as in the US or France [1]. They affect mostly infants and children but can spread also among adults [2,3]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - May 1, 2018 Category: Virology Authors: Mo Vareil, H. Wille, S. Kassab, C. Le-cornec, M. Puges, A. Desclaux, M.E. Lafon, C. Tumiotto, C. Cazanave, D. Neau Source Type: research
Editorial Board
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 26, 2018 Category: Virology Source Type: research
ESCV Membership
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 26, 2018 Category: Virology Source Type: research
PASCV Membership
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 26, 2018 Category: Virology Source Type: research
The risk of herpes simplex virus and human cytomegalovirus infection during pregnancy upon adverse pregnancy outcomes: A meta-analysis
Herpes simplex virus 1/2 (HSV-1/2) and human cytomegalovirus (HCMV) are members of the herpesvirus family and are known to cause widespread infection in humans, thus representing a serious global burden [1 –3]. HSV-1 is primarily transmitted by oral–oral contact and causes orolabial ulcers. In contrast, HSV-2 is primarily sexually transmitted and causes genital ulcers. The majority of HSV infections are asymptomatic or subclinical [4]. Looker et al. estimated that the global seroprevalence of HSV- 1 infection in 2012 was 67% while that of HSV-2 was 11% [1,2]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 25, 2018 Category: Virology Authors: Ting-li Shi, Li-Ju Huang, Yi-Quan Xiong, Yan-Yun Zhong, Jin-Jun Yang, Ting Fu, Xie-Fen Lei, Qing Chen Tags: Review Source Type: research
Outcome of a hepatitis B vaccination program for clients of a drug consumption facility
Hepatitis B is a viral infection of the liver associated with both acute and chronic manifestations. Worldwide, an estimated 240 million people are chronically infected with the hepatitis B virus, defined as carriers of the hepatitis B surface antigen (HBsAg) for at least 6 months Meireles et al., 2015; WHO, 2002/2017). People with chronic hepatitis B are at risk to develop liver cirrhosis and hepatocellular carcinoma and, importantly, are a relevant source for transmission of the virus to uninfected individuals. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 23, 2018 Category: Virology Authors: N. Scherbaum, J. Timm, F. Richter, U. Bonnet, J. Bombeck, S. Lajos, M. Specka Source Type: research
Cytomegalovirus sequence variability, amplicon length, and DNase-sensitive non-encapsidated genomes are obstacles to standardization and commutability of plasma viral load results
Cytomegalovirus represents a persisting challenge to transplant patients due to its direct and indirect effects decreasing graft and patient survival [1 –4]. Significant progress has been made in the clinical management of CMV replication post-transplantation through the concerted action of stratifying CMV risk according to CMV IgG serostatus of donor and recipient pairs, implementing prophylactic or preemptive antiviral strategies, and developing consensus definitions and guidelines [5–7]. Central to current medical practice is the sensitive and specific detection and quantification of CMV replication for clinical stu...
Source: Journal of Clinical Virology - April 21, 2018 Category: Virology Authors: Klaudia Naegele, Irmeli Lautenschlager, Rainer Gosert, Raisa Loginov, Katia Bir, Ilkka Helanter ä, Stefan Schaub, Nina Khanna, Hans H. Hirsch Source Type: research
Molecular epidemiology of human adenovirus infections in Denmark, 2011 –2016
Human adenoviruses (HAdVs) consist of seven different species (A to G) subdivided into 67 HAdV types [1,2]. HAdV typing is performed by PCR amplification and sequencing of a hypervariable region of the hexon gene, coding for one of three HAdV capsid proteins. HAdV can cause a wide range of diseases, namely febrile respiratory tract infections, conjunctivitis, diarrhoea and more rarely haemorrhagic cystitis and meningitis. Recent studies identified HAdV among 6% to 20% of hospitalised or emergency room admitted children [3 –6] presenting with lower respiratory tract infections and 10% and 23% of children admitted with acu...
Source: Journal of Clinical Virology - April 20, 2018 Category: Virology Authors: C éline Barnadas, Dennis Jelsbak Schmidt, Thea K. Fischer, Jannik Fonager Source Type: research
FALSE HUMAN CYTOMEGALOVIRUS IgG-POSITIVITY AT PRENATAL SCREENING
Human cytomegalovirus (HCMV) prenatal screening is not recommended in any country at the moment. However, a variable proportion of pregnant women is tested for HCMV IgG and IgM antibody in Europe [1]. In particular, in Italy about 40% of pregnant women are tested for HCMV on their gynecologist's or general practitioner's recommendation (personal data). To this purpose, fully automatized assays with a short turnaround are commonly used. Previous studies evaluated the overall performance of HCMV IgG commercial assays and results were reported as relative agreement between methods [2 –4]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 20, 2018 Category: Virology Authors: Milena Furione, Antonella Sarasini, Alessia Arossa, Fornara Chiara, Daniele Lilleri, Laurent Perez, Maurizio Parea, Maurizio Zavattoni, Arsenio Spinillo, Piero Marone, Fausto Baldanti Source Type: research
Molecular epidemiology of human adenovirus infections in Denmark, 2011-2016
Human adenoviruses (HAdVs) consist of seven different species (A to G) subdivided into 67 HAdV types [1,2]. HAdV typing is performed by PCR amplification and sequencing of a hypervariable region of the hexon gene, coding for one of three HAdV capsid proteins. HAdV can cause a wide range of diseases, namely febrile respiratory tract infections, conjunctivitis, diarrhoea and more rarely haemorrhagic cystitis and meningitis. Recent studies identified HAdV among 6% to 20% of hospitalized or emergency room admitted children [3 –6] presenting with lower respiratory tract infections and 10% and 23% of children admitted with acu...
Source: Journal of Clinical Virology - April 20, 2018 Category: Virology Authors: C éline Barnadas, Dennis Jelsbak Schmidt, Thea K. Fischer, Jannik Fonager Source Type: research
