Hepatitis E virus infection in different groups of Estonian patients and people who inject drugs
Hepatitis E virus (HEV) infection is a worldwide disease [1]. HEV is classified into at least four major mammalian genotypes and numerous subtypes. HEV genotypes appear to have a specific geographical distribution. To date, HEV genotypes 1 and 2 have only been reported to infect humans. They are commonly associated with a water-borne transmission route and are known to cause either sporadic cases or outbreaks in developing countries. Genotypes 3 and 4 appear to be responsible for acute sporadic cases and limited food-borne outbreaks in industrialized countries including Europe. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 19, 2018 Category: Virology Authors: Tatiana V. Kuznetsova, Anna Ivanova-Pozdejeva, Irina Reshetnjak, Julia Geller, Kairi V ärv, Reet Rumvolt, Maria Vikentjeva, Elena V. Trubnikova, Natalia V. Pozdniakova, Alexei B. Shevelev, Irina Golovljova Source Type: research
Viral bronchiolitis management in hospitals in the UK
In developed countries, viral bronchiolitis, in particular that caused by respiratory syncytial virus (RSV), is the leading cause of hospitalisation in infants less than a year old [1]. More than 30,000 infants are hospitalised each year in England and Wales due to viral bronchiolitis with a wide variation in rates of hospitalisation in different geographical regions of the United Kingdom (UK) [2 –4]. In one study hospitalisation rates varied between 351 and 5140 per 100 000 in English Primary Care Trusts [3]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 17, 2018 Category: Virology Authors: Elliott J. Carande, Eva P. Galiza, Alecia Nickless, Andrew J. Pollard, Simon B. Drysdale Source Type: research
Heterophilic interference in specimens yielding false-reactive results on the Abbott 4th generation ARCHITECT HIV Ag/Ab Combo assay
The recent publication of the CLSI-M53 HIV testing guidelines by the Clinical Laboratory Standards Institute (CLSI) and recommendations by the Centers for Disease Control and Prevention (CDC) represents the most significant change to HIV testing algorithms since the mid-1980 ’s (Fig. 1) [1,2]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 12, 2018 Category: Virology Authors: S. Lavoie, D. Caswell, M.J. Gill, K. Kadkhoda, C.L. Charlton, P.N. Levett, T. Hatchette, R. Garceau, J. Maregmen, T. Mazzulli, R. Needle, K. Kadivar, J. Kim Source Type: research
PNPLA3 rs738409 polymorphism is associated with liver fibrosis progression in patients with chronic hepatitis C: A repeated measures study
The natural course of chronic hepatitis C (CHC) varies widely among individuals [1], and the early recognition of patients at risk for developing liver fibrosis and cirrhosis is essential to take preventive measures that may affect the course of CHC [2]. Several risk factors have been associated with liver fibrosis progression, including age at infection, sex, route of infection, hepatitis C virus (HCV) genotype, and obesity among others [3]. In this regard, single nucleotide polymorphisms have been also associated with liver disease progression [3,4]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 12, 2018 Category: Virology Authors: Mar ía Ángeles Jiménez-Sousa, Ana Zaida Gómez-Moreno, Daniel Pineda-Tenor, Juan José Sánchez-Ruano, Amanda Fernández-Rodríguez, Tomas Artaza-Varasa, Alicia Gómez-Sanz, María Martín-Vicente, Sonia Vázquez-Morón, Salvador Resino Tags: Short communication Source Type: research
Heterophilic interference in specimens yielding false-reactive results on the Abbott 4th generation ARCHITECT HIV Ag/Ab Combo assay
The recent publication of the CLSI-M53 HIV testing guidelines by the Clinical Laboratory Standards Institute (CLSI) and recommendations by the Centers for Disease Control and Prevention (CDC) represents the most significant change to HIV testing algorithms since the mid-1980 ’s (Fig. 1) [1,2]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 12, 2018 Category: Virology Authors: S. Lavoie, D. Caswell, M.J. Gill, K. Kadkhoda, C.L. Charlton, P.N. Levett, T. Hatchette, R. Garceau, J. Maregmen, T. Mazzulli, R. Needle, K. Kadivar, J. Kim Source Type: research
PNPLA3 rs738409 polymorphism is associated with liver fibrosis progression in patients with chronic hepatitis C: a repeated measures study
The natural course of chronic hepatitis C (CHC) varies widely among individuals [1], and the early recognition of patients at risk for developing liver fibrosis and cirrhosis is essential to take preventive measures that may affect the course of CHC [2]. Several risk factors have been associated with liver fibrosis progression, including age at infection, sex, route of infection, HCV genotype, and obesity among others [3]. In this regard, single nucleotide polymorphisms have been also associated with liver disease progression [3,4]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 12, 2018 Category: Virology Authors: Mar ía Ángeles Jiménez-Sousa, Ana Zaida Gómez-Moreno, Daniel Pineda-Tenor, Juan José Sanchez-Ruano, Amanda Fernández-Rodríguez, Tomas Artaza-Varasa, Alicia Gómez-Sanz, María Martin-Vicente, Sonia Vázquez-Morón, Salvador Resino Tags: Short communication Source Type: research
Evaluation of the national laboratory-based surveillance system for respiratory syncytial virus in Sweden, 2015 –2016
Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infections, including bronchiolitis and pneumonia, in infants [1], as well as in the elderly and immunocompromised patients. RSV infections in these risk groups are associated with significant morbidity and mortality [2]. In temperate climates, RSV infections usually occur in seasonal outbreaks during late autumn, winter and early spring months [3]. In Sweden and other Nordic countries, RSV epidemics occur in a biennial pattern, with larger epidemics every other winter and milder epidemics during the interceding winters [4]. (Source: Jour...
Source: Journal of Clinical Virology - April 10, 2018 Category: Virology Authors: Heli Harvala, AnnaSara Carnahan, Sarah Axelsson, Maria Brytting Source Type: research
Evaluation of RIDA ®GENE norovirus GI/GII real time RT-PCR using stool specimens collected from children and adults with acute gastroenteritis
Globally, norovirus contributes to 18% of all diarrheal diseases and is associated with approximately 200,000 deaths each year [1]. Individuals from all age groups can be infected by norovirus [2]. Recent studies indicate that with the introduction of rotavirus vaccines (70 –80% uptake), norovirus has become the leading etiology for acute gastroenteritis (AGE) among children in the United States [3–5]. Although norovirus gastroenteritis is for most people a self-limiting disease, it may be life-threatening for young children, the elderly, and immunocompromised pati ents [2]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 10, 2018 Category: Virology Authors: N. Kanwar, F. Hassan, L. Barclay, C. Langley, J. Vinj é, P.W. Bryant, K. St. George, L. Mosher, J.M. Matthews-Greer, M.A. Rocha, D.O. Beenhouwer, C.J. Harrison, M. Moffatt, N. Shastri, R. Selvarangan Source Type: research
Clinical significance of IgM and IgA class anti-NMDAR antibodies in herpes simplex encephalitis
Herpes simplex encephalitis (HSE) is a devastating disease, in adults almost exclusively caused by herpes simplex virus type 1 (HSV-1). In its natural course the mortality is approximately 70% and even with current state-of-the-art treatment, patients often suffer severe and permanent disabilities [1 –4]. In addition to the cytopathic effect of HSV-1 infection in neuronal cells, the human immune response also causes cellular damage and death due to its necessary but imprecise attempts to control infection. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 10, 2018 Category: Virology Authors: Gabriel Westman, Azita Sohrabian, Elisabeth Aurelius, Clas Ahlm, Silvia Schliamser, Fredrik Sund, Marie Studahl, Johan R önnelid Source Type: research
Evaluation of the National Laboratory-based Surveillance System for Respiratory Syncytial Virus in Sweden, 2015-2016
Respiratory syncytial virus (RSV) is a common cause of severe lower respiratory tract infections, including bronchiolitis and pneumonia, in infants [1], as well as in the elderly and immunocompromised patients. RSV infections in these risk groups are associated with significant morbidity and mortality [2]. In temperate climates, RSV infections usually occur in seasonal outbreaks during late autumn, winter and early spring months [3]. In Sweden and other Nordic countries, RSV epidemics occur in a biennial pattern, with larger epidemics every other winter and milder epidemics during the interceding winters [4]. (Source: Jour...
Source: Journal of Clinical Virology - April 10, 2018 Category: Virology Authors: Heli Harvala, AnnaSara Carnahan, Sarah Axelsson, Maria Brytting Source Type: research
Evaluation of RIDA ®GENE Norovirus GI/GII Real Time RT-PCR Using Stool Specimens Collected from Children and Adults with Acute Gastroenteritis
Globally, norovirus contributes to 18% of all diarrheal diseases and is associated with approximately 200,000 deaths each year [1]. Individuals from all age groups can be infected by norovirus [2]. Recent studies indicate that with the introduction of rotavirus vaccines (70-80% uptake), norovirus has become the leading etiology for acute gastroenteritis (AGE) among children in the United States [3 –5]. Although norovirus gastroenteritis is for most people a self-limiting disease, it may be life-threatening for young children, the elderly, and immunocompromised patients [2]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 10, 2018 Category: Virology Authors: N. Kanwar, F. Hassan, L. Barclay, C. Langley, J. Vinj é, P.W. Bryant, K. St. George, L. Mosher, J.M. Matthews-Greer, M.A. Rocha, D.O. Beenhouwer, C.J. Harrison, M. Moffatt, N. Shastri, R. Selvarangan Source Type: research
Clinical significance of IgM and IgA class anti-NMDAR antibodies in herpes simplex encephalitis
Herpes simplex encephalitis (HSE) is a devastating disease, in adults almost exclusively caused by herpes simplex virus type 1 (HSV-1). In its natural course the mortality is approximately 70% and even with current state-of-the-art treatment, patients often suffer severe and permanent disabilities [1 –4]. In addition to the cytopathic effect of HSV-1 infection in neuronal cells, the human immune response also causes cellular damage and death due to its necessary but imprecise attempts to control infection. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 10, 2018 Category: Virology Authors: Gabriel Westman, Azita Sohrabian, Elisabeth Aurelius, Clas Ahlm, Silvia Schliamser, Fredrik Sund, Marie Studahl, Johan R önnelid Source Type: research
Editorial Board
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - April 5, 2018 Category: Virology Source Type: research
