Heterophilic interference in specimens yielding false-reactive results on the Abbott 4th generation ARCHITECT HIV Ag/Ab Combo assay

The recent publication of the CLSI-M53 HIV testing guidelines by the Clinical Laboratory Standards Institute (CLSI) and recommendations by the Centers for Disease Control and Prevention (CDC) represents the most significant change to HIV testing algorithms since the mid-1980 ’s (Fig. 1) [1,2].

Source: Journal of Clinical Virology - April 12, 2018 Category: Virology Authors: S. Lavoie, D. Caswell, M.J. Gill, K. Kadkhoda, C.L. Charlton, P.N. Levett, T. Hatchette, R. Garceau, J. Maregmen, T. Mazzulli, R. Needle, K. Kadivar, J. Kim Source Type: research