PNPLA3 rs738409 polymorphism is associated with liver fibrosis progression in patients with chronic hepatitis C: a repeated measures study

The natural course of chronic hepatitis C (CHC) varies widely among individuals [1], and the early recognition of patients at risk for developing liver fibrosis and cirrhosis is essential to take preventive measures that may affect the course of CHC [2]. Several risk factors have been associated with liver fibrosis progression, including age at infection, sex, route of infection, HCV genotype, and obesity among others [3]. In this regard, single nucleotide polymorphisms have been also associated with liver disease progression [3,4].
Source: Journal of Clinical Virology - Category: Virology Authors: Tags: Short communication Source Type: research