The Performance of Luminex ARIES ® Flu A/B & RSV and Cepheid Xpert ® Flu/RSV XC for the Detection of Influenza A, Influenza B, and Respiratory Syncytial Virus in Prospective Patient Samples
Influenza A, B, and respiratory syncytial virus (RSV) are common viral infections associated with easy transmission and significant morbidity and mortality [1,2]. The CDC currently recommends molecular influenza testing to be performed on hospitalized patients where a positive test would lead to a change in management and for identification of influenza outbreaks in health care facilities [1]. With the increasing demand for rapid, accurate test results, molecular based methods have been an expanding area of research and are increasingly used in both outpatient and inpatient clinical settings. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 5, 2017 Category: Virology Authors: Phillip McMullen, Sue Boonlayangoor, Angella Charnot-Katsikas, Kathleen G. Beavis, Vera Tesic Tags: Short communication Source Type: research
Transplacental Transfer of Maternal Respiratory Syncytial Virus (RSV) Antibody and Protection against RSV Disease in Infants in Rural Nepal
Pneumonia is the leading cause of childhood deaths in developing countries. Respiratory syncytial virus (RSV) is the most important cause of viral pneumonia in infants worldwide, with an estimated global burden of 64 million infections and 160,000 deaths annually. There are limited pharmacologic therapies and no licensed vaccine against RSV [1]. Advances in immunology and virology have accelerated the RSV vaccine field significantly in the past decade, and the World Health Organization has estimated that an RSV vaccine will be in clinical use within the next 5-10 years [2]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 2, 2017 Category: Virology Authors: Helen Y. Chu, James Tielsch, Joanne Katz, Amalia S. Magaret, Khatry Subarna, Stephen C. LeClerq, Laxman Shrestha, Jane Kuypers, Mark C. Steinhoff, Janet A. Englund Tags: Full length article Source Type: research
Interpretation of indeterminate HIV-1 PCR results are influenced by changing vertical transmission prevention regimens
Early treatment of human immunodeficiency virus (HIV)-infected infants reduces mortality in infants and limits viral reservoir size [1,2]. Testing for HIV in exposed newborn infants is therefore imperative. Demonstrating evidence of the virus for HIV diagnosis below 18 months of age is recommended by the WHO as maternally derived anti-HIV antibodies are present in HIV-exposed infants for this period [3]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 1, 2017 Category: Virology Authors: Jean Maritz, Jayshree Narvin Maharaj, Mark Frederic Cotton, Wolfgang Preiser Tags: Full length article Source Type: research
A European Multicientre Study on the Comparison of HBV Viral Loads Between VERIS HBV Assay and Roche COBAS ® TAQMAN® HBV test, Abbott RealTime HBV Assay, Siemens VERSANT HBV Assay, and Qiagen Artus HBV RG Kit
Hepatitis B viral load testing is essential to treatment and monitoring decisions in patients with chronic Hepatitis B. Beckman Coulter has developed the VERIS HBV Assay (Veris) for use on the fully automated DxN VERIS Molecular Diagnostics System ¥. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 1, 2017 Category: Virology Authors: Patrick Braun, Rafael Delgado, Monica Drago, Diana Fanti, Herv é Fleury, Jacques Izopet, Alessandra Lombardi, MaAngeles Marcos, Karine Sauné, Siobhan O'Shea, Alfredo Pérez-Rivilla, John Ramble, Pascale Trimoulet, Jordi Vila, Duncan Whittaker, Alain Art Tags: Full length article Source Type: research
A novel real-time RT-PCR assay for influenza C tested in Peruvian children
Influenza C virus (ICV) has been recognized as a cause of acute respiratory illness (ARI) in humans since 1947 [1]. However, since ICV is difficult to culture, the true burden of disease has remained unclear. Seroprevalence of ICV has been reported to be as high as 64% by 5 years of age, suggesting that many infections occur during early childhood [2 –5]. Recent RT-PCR studies suggest that ICV may be more commonly associated with ARI than previously thought [6–8]. However, ICV assays are not commercially available or widely tested in children. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - September 1, 2017 Category: Virology Authors: Leigh M. Howard, Monika Johnson, Ana I. Gil, Andrew Pekosz, Marie R. Griffin, Kathryn M. Edwards, Claudio F. Lanata, Carlos G. Grijalva, John V. Williams, for the RESPIRA-PERU Group Tags: Full length article Source Type: research
