PASCV Membership
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 20, 2017 Category: Virology Source Type: research
Real-Time RT-PCR for Mayaro Virus Detection in Plasma and Urine
Mayaro virus (MAYV) is a member of the Alphavirus genus (family Togaviridae) that is primarily transmitted by tree-dwelling Haemagogus species mosquitoes [1 –3]. Although originally isolated in Trinidad in 1954 [1,4], human cases have predominantly been detected in South America [1–3,5–8]. Three genotypes of MAYV have been identified (D, L, and N), with genotype D viruses causing the majority of cases [3,5]. Genotype L has almost exclusively been detected in Brazil, and only one strain of genotype N virus has been identified, in Peru [3,5]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 20, 2017 Category: Virology Authors: Jesse J. Waggoner, Alejandra Rojas, Alisha Mohamed-Hadley, Yvalena Ar évalo de Guillén, Benjamin A. Pinsky Tags: Short communication Source Type: research
Field performance of the Determine HBsAg point-of-care test for diagnosis of hepatitis B virus co-infection among HIV patients in Zambia
In Africa where the burden of hepatitis B virus is high, [1] rapid point-of-care (POC) tests are recommended to increase diagnostic capacity because they are low cost, temperature stable, and can be performed by lay health workers. [2,3] The World Health Organization recommends use of POC tests to identify patients with chronic HBV infection; however, real world data in Africa are limited on test performance and integration of HBV testing into the health system. Among available data two POC hepatitis B surface antigen (HBsAg) tests had sensitivities of 88.5 and 90.0% for diagnosis of HBV monoinfection in the Gambia when co...
Source: Journal of Clinical Virology - November 16, 2017 Category: Virology Authors: Caroline C. Chisenga, Kalo Musukuma, Roma Chilengi, Samuel Z ürcher, Virginia Munamunungu, Alice Siyunda, David Ojok, Sophie Bauer, Gilles Wandeler, Michael Vinikoor, for International Epidemiological Databases to Evaluate AIDS in Southern Africa (IeDEA- Tags: Short communication Source Type: research
Respiratory syncytial virus A in haematological patients with prolonged shedding: premature stop codons and deletion of the genotype ON1 72-nucleotide-duplication in the attachment G gene
Respiratory syncytial virus (RSV) is a frequent cause of upper respiratory tract infection but can be associated with prolonged and severe disease in immunocompromised patients, particularly in haematological stem cell recipients [1 –3]. Lower respiratory tract infections (LRTI) are associated with significant morbidity and mortality in these patients [2–4] and screening for RSV and other respiratory viruses like influenza and parainfluenza is strongly recommended [5]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 13, 2017 Category: Virology Authors: J. Tabatabai, A. Thielen, N. Lehners, M. Daeumer, P. Schnitzler Source Type: research
Cardiovascular complications in patients with Zika virus-induced Guillain-Barr é syndrome
Zika virus (ZV) predominantly causes mild symptoms like fever, rash, headache, conjunctivitis, joint and muscle pain. However, severe features including Guillain-Barr é syndrome (GBS), meningoencephalitis, myelitis, thrombocytopenic purpura, and microcephaly in the new-born were recorded, explaining why this mosquito-borne disease has rapidly become a challenging public health concern [1]. The first case of ZV infection in Martinique, French West Indies, was dia gnosed in December 2015. In December 2016, over 37,000 suspected cases were reported including thirty GBS cases, two newborns with microcephaly from 519 pregnant ...
Source: Journal of Clinical Virology - November 10, 2017 Category: Virology Authors: Dabor Resiere, Jean Louis Ferg é, Julien Fabre, Mathieu Raad, Signate Aitsatou, Jocelyn Inamo, André Cabié, B. Megarbane, H. Mehdaoui Tags: Letter to the editor Source Type: research
Neonatal and long-term ophthalmological findings in infants with symptomatic and asymptomatic congenital cytomegalovirus infection
Congenital Cytomegalovirus (CMV) infection is the most common congenital viral infection, with an estimated incidence of 0.6-2% of all live births [1,2]. It contributes to a high burden of disease and is recognized as the leading non-genetic cause of sensorineural hearing loss (SNHL) in children [3 –6]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 7, 2017 Category: Virology Authors: Maria Grazia Capretti, Concetta Marsico, Simonetta Guidelli Guidi, Antonio Ciardella, Giuliana Simonazzi, Silvia Galletti, Liliana Gabrielli, Tiziana Lazzarotto, Giacomo Faldella Source Type: research
Editorial Board
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 1, 2017 Category: Virology Source Type: research
ESCV Membership
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 1, 2017 Category: Virology Source Type: research
PASCV Membership
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 1, 2017 Category: Virology Source Type: research
The first external quality assessment of isolation and identification of influenza viruses in cell culture in the Asia Pacific region, 2016
Influenza viruses circulate worldwide and represent a continuous threat for human health. The ability to isolate and propagate influenza virus from clinical specimens is essential for ongoing surveillance of circulating virus strains and sharing of viruses. Historically, embryonated chicken eggs have been used to propagate influenza viruses [1,2] and currently most seasonal influenza vaccines are still produced in this substrate. Mammalian cell culture represents a simple, sensitive and cost-effective alternative for influenza virus isolation, particularly when many clinical specimens have to be processed (reviewed in [3])...
Source: Journal of Clinical Virology - November 1, 2017 Category: Virology Authors: Patrick C. Reading, Vivian K. Leung, Iwona Buettner, Leah Gillespie, Yi-Mo Deng, Robert Shaw, Natalie Spirason, Angela Todd, Kanta Subbarao, Aparna Singh Shah, Frank Konings, Ian G. Barr Source Type: research
Rotavirus detection in bulk stool and rectal swab specimens in children with acute gastroenteritis in Norway
Rotavirus group A (RVA) is the most common cause of acute gastroenteritis (AGE) in infants and young children under 5 years. Before the introduction of universal rotavirus vaccination in Norway, approximately 4.0 hospital inpatient and 2.3 outpatient cases per 1000 children with AGE under age 5 years were associated with a rotavirus infection annually. In addition, rotavirus-associated mortality was estimated at 0.17 deaths per 100,000 children (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 31, 2017 Category: Virology Authors: Moustafa Gibory, Ildri Haltbakk, Elmira Flem, Kirsti Vainio, Beatriz Valcarcel Salamanca, Ketil St ørdal, Svein Arne Nordbø, Kirsti Jakobsen, Elisebet Haarr, Susanne Gjeruldsen Dudman Tags: Full length article Source Type: research
Spectrum of HPV types before and after treatment of cervical intraepithelial neoplasia grade 2 and 3
Human papillomavirus (HPV) causes cervical cancer [1]. According to the International Agency on Cancer (IARC) classification, only 12 HPV types are classified as high risk (HR) HPV types and manifest carcinogenicity to humans and 13 are classified as probably or possibly carcinogenic of which five HPV types are based on phylogeny but without sufficient evidence in humans [2]. Several HPV types are regarded as low risk (LR) HPV types due to their low degree of association with human malignancy [3]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 26, 2017 Category: Virology Authors: Ylva Lindroth, Kaj Bjelkenkrantz, Ola Forslund Source Type: research
Outbreak of Chikungunya virus in a vulnerable population of Sergipe, Brazil —A molecular and serological survey
Chikungunya virus (CHIKV: Togaviridae: Alphavirus) is a mosquito-borne alphavirus mainly transmitted in urban and peri-urban areas by Aedes mosquitoes [1,2]. It was first described during a “dengue-like” outbreak in Tanzania between 1952-1953 [3]. In 2005, CHIKV caused a remarkable outbreak in La Réunion, a Madagascar island, with more than a third of its population testing positive for the infection [4]. The virus then spread across Asia, Europe, Pacific islands and the Americas, causing large outbreaks [2,5–8]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 25, 2017 Category: Virology Authors: Marielton dos Passos Cunha, Cliomar Alves dos Santos, Daniel Ferreira de Lima Neto, Alessandra Soares Schanoski, Shahab Zaki Pour, Saulo Duarte Passos, M ércia Simone Feitosa de Souza, Danuza Duarte Costa, Paolo Marinho de Andrade Zanotto Tags: Full length article Source Type: research
Epstein-Barr virus DNA load kinetics analysis in allogeneic hematopoietic stem cell transplant recipients: Is it of any clinical usefulness?
Epstein-Barr virus (EBV)-related post-transplant lymphoproliferative disorders (PTLDs) are a feared complication in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) because of its severe clinical course and high mortality rate [1]. Monitoring EBV DNA load in blood by real-time PCR has become a mainstay practice for estimating the risk of an impending PTLD, triggering the implementation of preventative strategies (such as a reduction in immunosuppression or initiation of preemptive therapy with rituximab), and for assessing therapeutic responses in cases of high-level EBV DNAemia or PTLDs [...
Source: Journal of Clinical Virology - October 25, 2017 Category: Virology Authors: Carlos Solano, Eva Mar ía Mateo, Ariadna Pérez, Alberto Talaya, María José Terol, Eliseo Albert, Estela Giménez, Víctor Vinuesa, José Luis Piñana, Juan Carlos Hernández Boluda, David Navarro Tags: Full length article Source Type: research
Detection and differentiation of HIV-2 using the point-of-care Alere q HIV-1/2 Detect nucleic acid test
HIV-2 is endemic in West Africa with limited global spread primarily to countries with socio-economic ties to the region [1 –4]; there are an estimated 1–2 million patients infected with HIV-2 worldwide [5–7]. Compared to HIV-1, patients infected with HIV-2 often have a longer asymptomatic stage, slower decline in CD4+T-cells and decreased acquired immunodeficiency syndrome (AIDS)-associated mortality [8–11]. In areas where HIV-2 and HIV-1 co-circulate, a substantial number of patients are dually-infected with both HIV types [12–14]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - October 25, 2017 Category: Virology Authors: Ming Chang, Katrin Steinmetzer, Dana N. Raugi, Robert A. Smith, Selly Ba, Fatima Sall, Moussa Seydi, Alassane Niang, ElHadji Ibrahima Sall, Ousseynou Cisse, Katja R ödel, Robert W. Coombs, Geoffrey S. Gottlieb Tags: Full length article Source Type: research
