Lack of Zika virus antibody response in confirmed patients in non-endemic countries
Zika virus (ZIKV) has spread in the last 2 years throughout America and South-Eastern Asia causing a widespread epidemic [1]. Detection of ZIKV RNA in body fluids confirms ZIKV infection, however ZIKV antibody testing is much more complex due to possible cross-reactivity with closely related flaviviruses [2]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 21, 2017 Category: Virology Authors: Yaniv Lustig, Ani Ioana Cotar, Cornelia S. Ceianu, Concetta Castilletti, Hana Zelena, Elisa Burdino, Carla van Tienen, Tatjana Avsic, Emma Aarons, Chantal Reusken Tags: Letter to the editor Source Type: research
Safety and acceptability of human papillomavirus testing of self-collected specimens: a methodologic study of the impact of collection devices and HPV assays on sensitivity for cervical cancer and high-grade lesions
A high participation rate is essential for an effective screening programme. A variety of personal and provider level factors influence screening participation [1,2]. One promising approach to reach screening non-responders is to offer them self-collection devices for high-risk human papillomavirus (hrHPV) testing [3 –6]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 21, 2017 Category: Virology Authors: Maarit K. Leinonen, Kristina Schee, Christine M. Jonassen, A. Kathrine Lie, Camilla F. Nystrand, Anbj ørg Rangberg, Ingegerd E. Furre, Marzena J. Johansson, Ameli Tropé, Katrine D. Sjøborg, Philip E. Castle, Mari Nygård Source Type: research
Comparative evaluation of the CerTest VIASURE flu A, B & RSV real time RT-PCR detection kit on the BD MAX system versus a routine in-house assay for detection of influenza a and B virus during the 2016/17 influenza season
Fast and accurate diagnosis of influenza can reduce unnecessary antimicrobial treatment, laboratory testing and isolation of patients[1,2]. It is of interest to assess commercial alternatives to in-house assays that may not only reduce the turnaround time in the laboratory. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 21, 2017 Category: Virology Authors: Thomas Vognbjerg Sydenham, Malene Bek-Thomsen, Signe Dalsgaard Andersen, Birte Kolmos, Ea Sofie Marmolin, Ramona Trebbien, Jens Kj ølseth Møller Tags: Short communication Source Type: research
A European multicenter study on the analytical performance of the VERIS HBV assay
Hepatitis B virus (HBV) is estimated to affect 400 million people worldwide, with approximately 240 million chronically infected [1 –3]. Individuals with chronic HBV are at increased risk of developing cirrhosis, hepatic decompensation, and hepatocellular carcinoma (HCC) [1,2,4–6] and elevations in HBV DNA viral levels have been shown to be associated with both risk of progression to cirrhosis and risk of HCC [7–10]. Measu rement of HBV viral loads (VL) is an essential part of the management of chronic HBV with regard to treatment start, predicting treatment response, and monitoring treatment resistance. (Source: Jou...
Source: Journal of Clinical Virology - December 19, 2017 Category: Virology Authors: Patrick Braun, Rafael Delgado, Monica Drago, Diana Fanti, Herv é Fleury, Jacques Izopet, Alessandra Lombardi, Alessandro Mancon, Maria Angeles Marcos, Karine Sauné, Siobhan O′Shea, Alfredo Pérez-Rivilla, John Ramble, Pascale Trimoulet, Jordi Vila, Du Source Type: research
A European Multicientre Study on the Analytical Performance of the VERIS HBV Assay
Hepatitis B virus (HBV) is estimated to affect 400 million people worldwide, with approximately 240 million chronically infected [1 –3]. Individuals with chronic HBV are at increased risk of developing cirrhosis, hepatic decompensation, and hepatocellular carcinoma (HCC) [1,2,4–6] and elevations in HBV DNA viral levels have been shown to be associated with both risk of progression to cirrhosis and risk of HCC [7–10]. Measu rement of HBV viral loads (VL) is an essential part of the management of chronic HBV with regard to treatment start, predicting treatment response, and monitoring treatment resistance. (Source: Jou...
Source: Journal of Clinical Virology - December 19, 2017 Category: Virology Authors: Patrick Braun, Rafael Delgado, Monica Drago, Diana Fanti, Herv é Fleury, Jacques Izopet, Alessandra Lombardi, Alessandro Mancon, Mª Angeles Marcos, Karine Sauné, Siobhan O'Shea, Alfredo Pérez-Rivilla, John Ramble, Pascale Trimoulet, Jordi Vila, Duncan Source Type: research
Diagnostic performances of the Xpert ® Flu PCR test and the OSOM® immunochromatographic rapid test for influenza A and B virus among adult patients in the Emergency Department
Respiratory viruses are responsible for significant morbidity and mortality in both children and adults [1]. The predictive value of symptoms and clinical signs for the diagnosis of influenza is very low, regardless of the viral strain involved [2 –6]. Early implementation of antiviral treatment and isolation measures depend on rapid diagnosis of influenza [7–10]. Moreover, the use of testing for respiratory viruses within the ED in adults was recently associated with shorter duration of antibiotics and length of stay [8]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 13, 2017 Category: Virology Authors: Stephanie Antoniol, Nadhira Fidouh, Aiham Ghazali, Houria Ichou, Donia Bouzid, Philippe Kenway, Christophe Choquet, Benoit Visseaux, Enrique Casalino, the Emergency Department study group on respiratory viruses Source Type: research
Performance Evaluation of the Aptima HSV-1 and 2 Assay for the Detection of HSV in cutaneous and mucocutaneous lesion specimens
Worldwide, herpes simplex viruses (HSV) have a great impact on human health due to high prevalence, sexual transmissibility rate, impact on immunocompromised patients and disease recurrence [1,2]. HSV-1 and HSV-2 are responsible for a variety of human diseases affecting all age groups, of which cutaneous and mucocutaneous infections are the most common [3,4]. Accurate diagnosis of HSV-1 and HSV-2 infections is critical to improve counseling, treatment, and preventing transmission. While conventional and modified cell culture have been the traditional approaches to detect HSV from cutaneous and mucocutaneous lesions, molecu...
Source: Journal of Clinical Virology - December 13, 2017 Category: Virology Authors: Soya S. Sam, Angela M. Caliendo, Jessica Ingersoll, Deborah Abdul-Ali, Colleen S. Kraft Source Type: research
A chip-based rapid genotyping assay to discriminate between rhinovirus species A, B and C
Human rhinoviruses (RVs) are the most common causative agents of upper respiratory tract infection in humans [1]. They were previously considered to cause only relatively mild illness; yet cumulative associations with severe disease of the respiratory tract, including bronchitis, pneumonia, and exacerbations of chronic pulmonary disease have been reported [2 –5]. Additionally, RV infection has been described to induce wheezing in early infancy and is suggested to be an important risk factor for development of severe asthma [6–8]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 8, 2017 Category: Virology Authors: Brenda M. Westerhuis, Maryse A. Wiewel, Alexander am Ende, Lonneke van der Linden, Sylvie M. Koekkoek, Katja C. Wolthers, Olfert Landt Source Type: research
Respiratory syncytial virus in Brazilian infants – Ten years, two cohorts
Acute Viral Bronchiolitis (AVB) is the most common cause of hospitalization among infants during the first 12 months of life [1]. A variety of viral etiologies are known to cause AVB, particularly the respiratory syncytial virus (RSV) [2]. The RSV virus has two subtypes, A and B, which occur in different frequencies and combinations each year [3,4]. About 10% of the AVB cases demand hospitalization; mortality rates are 1% or less, mainly in cases with associated co-morbidities [5]. An effective vaccine is not available; current treatment is only supportive; preventive measures are limited to very expensive monoclonal antib...
Source: Journal of Clinical Virology - December 6, 2017 Category: Virology Authors: Elinara Wollmeister, Alfonso Eduardo Alvarez, Juliana Cristina Santiago Bastos, Fernando Augusto Lima Marson, Jos é Dirceu Ribeiro, Emilio Carlos Elias Baracat, Clarice Weis Arns, Adriana Gut Lopes Riccetto Tags: Short communication Source Type: research
HPeV-3 predominated among Parechovirus A positive infants during an outbreak in 2013 –2014 in Queensland, Australia
The species Parechovirus A include human parechovirus (HPeV) type 1 and 2, first identified in 1956 as echovirus 22 and 23 [1,2]. There are now 19 HPeV genotypes within the genus Parechovirus, family Picornaviridae [1]. Infection has been associated with respiratory [3,4] and gastrointestinal disease [4,5]. Young children are more likely than adults to suffer aseptic meningitis [4], encephalitis, flaccid paralysis and severe neonatal sepsis [4,6 –10]. Long term neurodevelopmental sequelae from HPeV infection have also been suggested [11]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 5, 2017 Category: Virology Authors: Donna McNeale, Claire Y.T. Wang, Katherine E. Arden, Ian M. Mackay Tags: Short communication Source Type: research
Assessment of the roche linear array hpv genotyping test within the valgent framework
In 2012, the International Agency for Research on Cancer (IARC) concluded that at least 12 high-risk human papillomavirus (hrHPV) types (HPV16, HPV18, HPV31, HPV33, HPV35, HPV3, HPV45, HPV51, HPV52, HPV56, HPV58 and HPV59), were carcinogenic to humans for the development of cervical cancer (IARC-2009 hrHPV types)[1]. Furthermore, it has been demonstrated through several randomized controlled trials that hrHPV DNA testing is more effective than cervical cytology in primary screening of women aged 30 years or older [2,3]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 5, 2017 Category: Virology Authors: Lan Xu, Anja O štrbenk, Mario Poljak, Marc Arbyn Source Type: research
HPeV-3 predominated among Parechovirus A positive infants during an outbreak in 2013-2014 in Queensland, Australia
The species Parechovirus A include human parechovirus (HPeV) type 1 and 2, first identified in 1956 as echovirus 22 and 23 [1,2]. There are now 19 HPeV genotypes within the genus Parechovirus, family Picornaviridae [1]. Infection has been associated with respiratory [3,4] and gastrointestinal disease [4,5]. Young children are more likely than adults to suffer aseptic meningitis [4], encephalitis, flaccid paralysis and severe neonatal sepsis [4,6 –10]. Long term neurodevelopmental sequelae from HPeV infection have also been suggested [11]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - December 5, 2017 Category: Virology Authors: Donna McNeale, Claire Y.T. Wang, Katherine E. Arden, Ian M. Mackay Tags: Short communication Source Type: research
Radiotherapy-induced reactivation of neurotrophic human herpes viruses: overview and management
Infection by Human Herpes Viruses (HHV), types 1-3, are prevalent throughout the world [1,2]. It is known that cancer radiotherapy can reactivate HHV, but it is unclear how and to what extent reactivations can interact with or affect radiotherapeutic efficacy and patient outcomes (e.g., worsening of acute toxicities, inducing tumor radio-resistance). There are two in vitro studies, to date, that suggest an association between herpetic reactivation and radio-resistance [3,4]. (Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 22, 2017 Category: Virology Authors: Marigdalia K. Ramirez-Fort, Jianying Zeng, Amir Feily, Luis A. Ramirez-Pacheco, Joseph M. Jenrette, David L. Mayhew, Talal Syed, S. Lewis Cooper, Craig Linden, Witney S. Graybill, Lars E. French, Christopher S. Lange Tags: Review Source Type: research
Editorial Board
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 20, 2017 Category: Virology Source Type: research
ESCV Membership
(Source: Journal of Clinical Virology)
Source: Journal of Clinical Virology - November 20, 2017 Category: Virology Source Type: research
