Performance Evaluation of the Aptima HSV-1 and 2 Assay for the Detection of HSV in cutaneous and mucocutaneous lesion specimens

Worldwide, herpes simplex viruses (HSV) have a great impact on human health due to high prevalence, sexual transmissibility rate, impact on immunocompromised patients and disease recurrence [1,2]. HSV-1 and HSV-2 are responsible for a variety of human diseases affecting all age groups, of which cutaneous and mucocutaneous infections are the most common [3,4]. Accurate diagnosis of HSV-1 and HSV-2 infections is critical to improve counseling, treatment, and preventing transmission. While conventional and modified cell culture have been the traditional approaches to detect HSV from cutaneous and mucocutaneous lesions, molecular methods are more widely used in clinical laboratories.

Source: Journal of Clinical Virology - December 13, 2017 Category: Virology Authors: Soya S. Sam, Angela M. Caliendo, Jessica Ingersoll, Deborah Abdul-Ali, Colleen S. Kraft Source Type: research