FALSE HUMAN CYTOMEGALOVIRUS IgG-POSITIVITY AT PRENATAL SCREENING

Human cytomegalovirus (HCMV) prenatal screening is not recommended in any country at the moment. However, a variable proportion of pregnant women is tested for HCMV IgG and IgM antibody in Europe [1]. In particular, in Italy about 40% of pregnant women are tested for HCMV on their gynecologist's or general practitioner's recommendation (personal data). To this purpose, fully automatized assays with a short turnaround are commonly used. Previous studies evaluated the overall performance of HCMV IgG commercial assays and results were reported as relative agreement between methods [2 –4].
Source: Journal of Clinical Virology - Category: Virology Authors: Source Type: research