The risk of herpes simplex virus and human cytomegalovirus infection during pregnancy upon adverse pregnancy outcomes: A meta-analysis

Herpes simplex virus 1/2 (HSV-1/2) and human cytomegalovirus (HCMV) are members of the herpesvirus family and are known to cause widespread infection in humans, thus representing a serious global burden [1 –3]. HSV-1 is primarily transmitted by oral–oral contact and causes orolabial ulcers. In contrast, HSV-2 is primarily sexually transmitted and causes genital ulcers. The majority of HSV infections are asymptomatic or subclinical [4]. Looker et al. estimated that the global seroprevalence of HSV- 1 infection in 2012 was 67% while that of HSV-2 was 11% [1,2].
Source: Journal of Clinical Virology - Category: Virology Authors: Tags: Review Source Type: research