Recovery of cytomegalovirus DNA from newborn saliva samples by different methods

Cytomegalovirus (CMV) is the most common congenital infection [1,2] and a leading cause of childhood hearing loss, cognitive deficits and visual impairment [3,4]. Diagnosis of congenital CMV infection (cCMV) allows affected infants optimal monitoring and interventions [5 –8]. A definitive diagnosis of cCMV requires viral detection within the first 21 days of life because postnatal acquisition of CMV is common in early infancy and is associated with less morbidity. Large amounts of CMV are continuously shed in the saliva and urine of congenitally infected newborn s [9].

Source: Journal of Clinical Virology - May 5, 2018 Category: Virology Authors: Oran Goshen, David M. Goldfarb, Book Laura, Peter Tilley, Soren Gantt Source Type: research