Title page
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 29, 2016 Category: Hematology Source Type: research
Editorial Board
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 29, 2016 Category: Hematology Source Type: research
Table of Contents
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 29, 2016 Category: Hematology Source Type: research
Aims and Scope
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 29, 2016 Category: Hematology Source Type: research
Clinical studies of ex vivo expansion to accelerate engraftment after umbilical cord blood transplantation: a systematic review
Cell dose limits greater use of umbilical cord blood (UCB) in hematopoietic cell transplantation (HCT). The clinical benefits of ex vivo expansion needs clarity to understand its potential impact. A systematic search of studies addressing UCB ex vivo expansion was conducted. 15 clinical studies (349 transplanted patients) and 13 registered trials were identified. The co-infusion of an expanded unit and a second unmanipulated unit (8 studies), the fractional expansion of a 12 –60% of a single unit (5 studies) and the infusion of a single expanded unit (2 studies) were reported. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 22, 2016 Category: Hematology Authors: Jeffrey Kiernan, Pauline Damien, Madeline Monaghan, Risa Shorr, Lauralyn McIntyre, Dean Fergusson, Alan Tinmouth, David Allan Tags: Clinical Trial Source Type: research
Transfusion Medicine in China Comes of Age
Nearly 1.4 billion people live in China whose population represents almost 1 in every 5 people on Earth. In recent decades, the nation has witnessed tremendous economic growth accompanied by dramatic social, political, and scientific change. Healthcare in China is rapidly evolving and transfusion medicine has been very much a part of the challenges and opportunities confronting the nation. In this special issue of Transfusion Medicine Reviews, we offer readers a glimpse of current transfusion medicine in China. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 14, 2016 Category: Hematology Authors: Hua Shan, Ling Shi Source Type: research
Platelet Immunology in China: Research and Clinical Applications
Immunization against human platelet alloantigens (HPAs) is associated with a number of clinical complications. The detection and identification of clinically relevant platelet antibodies are important for the diagnosis and management of patients affected with immune-mediated thrombocytopenias. Human platelet alloantigen frequencies and the characteristics of antiplatelet antibodies vary widely between ethnic groups. Since 2008, the importance of platelet immunology in the field of transfusion medicine has gained greater recognition by clinical laboratories in China. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 5, 2016 Category: Hematology Authors: Guoguang Wu, Yan Zhou, Lilan Li, Zhoulin Zhong, Hengchong Li, Haiyan Li, Mei Yu, Weidong Shen, Heyu Ni Source Type: research
Challenges and Research in Managing Blood Supply in China
This article describes three of these important and less-emphasized issues: Firstly, the ambiguity of the definition of voluntary non-remunerated blood donation, and its relationship to an adequate blood supply; secondly, the current inadequacies of cost recovery from the blood service system; and thirdly, the lack of a universally implemented program of hemovigilance. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 2, 2016 Category: Hematology Authors: Yongming Zhu, Dongfu Xie, Xun Wang, Kaicheng Qian Source Type: research
Plasma transfusion in patients with cirrhosis in China: A retrospective multicenter cohort study
Cirrhosis patients used to be associated with frequent use of blood components due to their complex disorder of hemostasis and bleeding complications. Recent findings have indicated that cirrhosis patients have a state of “rebalanced” or even procoagulant hemostasis and have questioned the prophylactic use of plasma. In order to evaluate the current status of plasma use in cirrhosis patients, we conducted a retrospective survey in 11 tertiary-care hospitals in China from September 1 to October 31, 2013. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 1, 2016 Category: Hematology Authors: Yao Lu, Guixiang Sun, Xiangfu Liu, Zhiguo Liu, Jianguo Tan, Yiwen Hao, Guiqiu Shan, Qun Luo, Deqing Wang, Yanchao Xing, Xianqing Zhang, Jiwu Gong, Simon J Stanworth, Jun Wang, Aiqing Wen Source Type: research
Research Progress of Platelet Transfusion in China
Platelet products have been increasingly used for more than fifty years. Platelet transfusion is effective for correcting bleeding caused by thrombocytopenia and platelet function defects. In this review, we will outline research on platelet transfusion in China including platelet biosafety, cryopreservation of platelets, the assessment of the effectiveness of platelet transfusion, the causes of platelet transfusion refractoriness (PTR) including immunisation against CD36, and neonatal alloimmune thrombocytopenia (NAIT). (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - November 26, 2016 Category: Hematology Authors: Qiushi Wang, Jiangcun Yang, Lori Stevens, Deqing Wang Tags: Review Source Type: research
Red Cell Immunohematology Research Conducted in China
ABO subtypes and RhD variants are the most studied blood groups in China. Some of the polymorphisms in these two blood groups have direct clinical relevance. Molecular diagnosis of blood group polymorphisms is underway in China. In addition, research groups have developed methods such as screening for blood group mimetic peptides using phage display technology. New reagents, akin to antibodies directed against RhD and ABO, are being investigated using aptamer-based techniques. Progress is also being made in the development of synthetic exoglycosidases for conversion of group A and/or B antigens to group O. (Source: Transfu...
Source: Transfusion Medicine Reviews - November 23, 2016 Category: Hematology Authors: Ziyan Zhu, Yuli Ye, Qin Li, Hongwei Gao, Yinxia Tan, Wei Cai Source Type: research
Designing and Implementing a 5-Year Transfusion Medicine Diploma Program in China
The need for physicians and technical consultants specialized in transfusion medicine is urgent in China, as there are 20 000 hospitals and 500 blood centers in need of staff with this expertise. The progress made in transfusion medicine as a specialty has been relatively slow in China. Current Chinese medical education and service systems have not developed transfusion medicine as a stand-alone medical specialty. Most physicians receive only minimal training in transfusion medicine in medical school. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - November 15, 2016 Category: Hematology Authors: Tingting Li, Wenjing Wang, Ling Zhang, Ye Zhou, Fucai Lai, Yongshui Fu, Chuanxi Wang, Baocheng Yang, Weigang Zhu, Yanyun Wu, Jean-Pierre Allain, Lori Stevens, Chengyao Li Source Type: research
Designing and implementing a five-year transfusion medicine diploma program in China
The need for physicians and technical consultants specialized in transfusion medicine is urgent in China, as there are twenty thousand hospitals and five hundred blood centers in need of staff with this expertise. The progress made in transfusion medicine as a specialty has been relatively slow in China. Current Chinese medical education and service systems have not developed transfusion medicine as a stand-alone medical specialty. Most physicians receive only minimal training in transfusion medicine in medical school. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - November 15, 2016 Category: Hematology Authors: Tingting Li, Wenjing Wang, Ling Zhang, Ye Zhou, Fucai Lai, Yongshui Fu, Chuanxi Wang, Baocheng Yang, Weigang Zhu, Yanyun Wu, Jean-Pierre Allain, Lori Stevens, Chengyao Li Source Type: research
The role of the laboratory and transfusion service in the management of Ebola Virus Disease
The Ebola outbreak that began in 2013 infected and killed record numbers of individuals and created unprecedented challenges, including containment and treatment of the virus in resource-strained West Africa as well as the repatriation and treatment of patients in the United States and Europe. Valuable lessons were learned, especially the important role that the laboratory and transfusion service plays in the treatment of patients with Ebola virus disease (EVD) by providing data for supportive care and fluid resuscitation as well as the generation of investigational therapies such as convalescent plasma (CP). (Source: Tran...
Source: Transfusion Medicine Reviews - November 15, 2016 Category: Hematology Authors: Scott A. Koepsell, Anne M. Winkler, John D. Roback Source Type: research
The history and challenges of blood donor screening in China
Since the establishment of People's Republic of China in 1949, the Chinese government has encountered several catastrophes related to transfusion transmitted diseases. The government's increasing attention to blood safety has prompted the initiation of a series of policies and measures which have enhanced the level of safety for the blood supply, and met the basic clinical demands of blood for 1.3 billion people in the country.Blood donation screening strategies in China are predominantly comprised of donor screening and donor testing. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - November 11, 2016 Category: Hematology Authors: Ling Li, Yi Li Ka, Ke Yan, Guojin Ou, Wenhui Li, Jue Wang, Ning Song, Li Tian, Xin Ji, Yongjun Chen, Xiaohua Liang, Zhong Liu, Yanyun Wu Source Type: research
