Red Cell Immunohematology Research Conducted in China

ABO subtypes and RhD variants are the most studied blood groups in China. Some of the polymorphisms in these two blood groups have direct clinical relevance. Molecular diagnosis of blood group polymorphisms is underway in China. In addition, research groups have developed methods such as screening for blood group mimetic peptides using phage display technology. New reagents, akin to antibodies directed against RhD and ABO, are being investigated using aptamer-based techniques. Progress is also being made in the development of synthetic exoglycosidases for conversion of group A and/or B antigens to group O.

Source: Transfusion Medicine Reviews - November 23, 2016 Category: Hematology Authors: Ziyan Zhu, Yuli Ye, Qin Li, Hongwei Gao, Yinxia Tan, Wei Cai Source Type: research