Acquired Factor XIII Inhibitor In Hospitalized And Perioperative Patients: A Systematic Review Of Case Reports And Case Series
Factor XIII (FXIII) cross-links fibrin monomers to support clot stabilization and wound healing. Acquired FXIII deficiency is caused by autoantibodies that inhibit FXIII, and can result in bleeding despite normal routine coagulation tests. Given the rarity of this disease large clinical studies are not feasible. We therefore conducted a systematic review of case reports and case series of acquired FXIII inhibitor to evaluate potential management and treatment strategies for acquired FXIII inhibitor in hospitalized and/or perioperative patients. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - April 20, 2016 Category: Hematology Authors: Kira J. Tone, Tyler E. James, Dean A. Fergusson, Alan Tinmouth, Jason Tay, Marc T. Avey, Shaun Kilty, Manoj M. Lalu Source Type: research
Toxoplasmosis in Blood Donors: A Systematic Review and Meta-Analysis
The objective of this review was to comprehensively assess the seroprevalence rate of Toxoplasma in blood donors from a worldwide perspective. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 29, 2016 Category: Hematology Authors: Masoud Foroutan-Rad, Hamidreza Majidiani, Sahar Dalvand, Ahmad Daryani, Wesam Kooti, Jasem Saki, Faezeh Hedayati-Rad, Ehsan Ahmadpour Tags: Original Article Source Type: research
Toxoplasmosis in blood donors: A systematic review and meta-analysis
The objective of this review was to comprehensively assess the seroprevalence rate of Toxoplasma in blood donors from a worldwide perspective. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 29, 2016 Category: Hematology Authors: Masoud Foroutan-Rad, Hamidreza Majidiani, Sahar Dalvand, Ahmad Daryani, Wesam Kooti, Jasem Saki, Faezeh Hedayati-Rad, Ehsan Ahmadpour Source Type: research
CAR-T Cell Therapies From the Transfusion Medicine Perspective
The use of chimeric antigen receptor (CAR)-T cell therapy for the treatment of hematologic malignancies has generated significant excitement over the last several years. From a transfusion medicine perspective, the implementation of CAR-T therapy as a potential mainstay treatment for not only hematologic but also solid-organ malignancies represents a significant opportunity for growth and expansion. In this review, we will describe the rationale for the development of genetically redirected T cells as a cancer therapeutic, the different elements that are required to engineer these cells, as well as an overview of the proce...
Source: Transfusion Medicine Reviews - March 27, 2016 Category: Hematology Authors: Andrew Fesnak, ChieYu Lin, Don L. Siegel, Marcela V. Maus Source Type: research
CAR-T Cell Therapies from the Transfusion Medicine Perspective
The use of chimeric antigen receptor (CAR)-T cell therapy for the treatment of hematologic malignancies has generated significant excitement over the last several years. From a transfusion medicine perspective, the implementation of CAR-T therapy as a potential mainstay treatment for not only hematologic but also solid-organ malignancies represents a significant opportunity for growth and expansion. In this review, we will describe the rationale for the development of genetically re-directed T-cells as a cancer therapeutic, the different elements that are required to engineer these cells, as well as an overview of the proc...
Source: Transfusion Medicine Reviews - March 27, 2016 Category: Hematology Authors: Andrew Fesnak, ChieYu Lin, Don L. Siegel, Marcela V. Maus Source Type: research
Masthead
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 25, 2016 Category: Hematology Source Type: research
Title page
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 25, 2016 Category: Hematology Source Type: research
Editorial Board
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 25, 2016 Category: Hematology Source Type: research
Contents
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 25, 2016 Category: Hematology Source Type: research
Aims and Scope
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 25, 2016 Category: Hematology Source Type: research
Journal Club
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 1, 2016 Category: Hematology Authors: Richard Haspel, Simon Stanworth, Jeannie Callum Source Type: research
Effect of Blood Donor Characteristics on Transfusion Outcomes: A Systematic Review and Meta-Analysis
Optimal selection of blood donors is critical for ensuring the safety of blood products. The current selection process is concerned principally with the safety of the blood donor at the time of donation and of the recipient at the time of transfusion. Recent evidence suggests that the characteristics of the donor may affect short- and long-term transfusion outcomes for the transfused recipient. We conducted a systematic review with the primary objective of assessing the association between blood donor characteristics and red blood cell (RBC) transfusion outcomes. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - February 23, 2016 Category: Hematology Authors: Michaël Chassé, Lauralyn McIntyre, Shane W. English, Alan Tinmouth, Greg Knoll, Dianna Wolfe, Kumanan Wilson, Nadine Shehata, Alan Forster, Carl van Walraven, Dean A. Fergusson Source Type: research
Blood-borne Pathogens: A Canadian Blood Services Centre for Innovation Symposium
Testing donations for pathogens and deferring selected blood donors have reduced the risk of transmission of known pathogens by transfusion to extremely low levels in most developed countries. Protecting the blood supply from emerging infectious threats remains a serious concern in the transfusion medicine community. Transfusion services can employ indirect measures such as surveillance, hemovigilance, and donor questioning (defense), protein- or nucleic acid based direct testing (detection), or pathogen inactivation of blood products (destruction) as strategies to mitigate the risk of transmission-transmitted infection (T...
Source: Transfusion Medicine Reviews - February 22, 2016 Category: Hematology Authors: Geraldine M. Walsh, Andrew W. Shih, Ziad Solh, Mia Golder, Peter Schubert, Margaret Fearon, William P. Sheffield Source Type: research
How can we improve retention of the first-time donor? A systematic review of the current evidence
Blood products are critical to health systems and donations by voluntary non-remunerated donors are recommended. Worldwide, however, only around 5% of those eligible to donate do so and around half of those never return to donate again. This review focuses on what deters first-time donors, what predicts their retention, and what interventions may promote retention of this group. A comprehensive search of relevant databases identified 9 studies investigating motives and deterrents of first-time donors, 14 studies investigating predictors for first-time donors (13 whole blood [WB] and 2 plasmapheresis) and 15 studies (in 14 ...
Source: Transfusion Medicine Reviews - February 17, 2016 Category: Hematology Authors: Kathleen L. Bagot, Andrea L. Murray, Barbara M. Masser Source Type: research
Tranexamic acid for prevention PPH: a promising drug but today only a promising drug
We congratulate Alam and Choi for their excellent systematic review regarding the use of tranexamic acid (TXA) to prevent postpartum blood loss and postpartum hemorrhage (PPH) after both cesarean and vaginal deliveries [1]. We would like in particular to congratulate the authors for their main caution take-home message and their excellent critical analysis of the quality of the available evidence: more evidences are necessary before implementing TXA in routine practice for all deliveries. As we previously highlighted in a non-systematic review [2], Alam and Choi have underlined the weakness of the existing literature as ar...
Source: Transfusion Medicine Reviews - February 8, 2016 Category: Hematology Authors: Loïc Sentilhes, Stéphanie Brun, Hugo Madar, Catherine Deneux-Tharaux Source Type: research
