Aims and Scope
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - April 1, 2015 Category: Hematology Source Type: research
Response to the Article on Dimethyl Sulfoxide–Cryopreserved Platelets Published in Transfusion Medicine Reviews Volume 28(4)
We were interested in the article “Review of in vivo studies of dimethyl sulfoxide cryopreserved platelets” by Slichter et al [1] and would like to draw attention to our work in this field, which is described in the monograph “Non-surgical bleeding diathesis in anemic thrombocytopenic patients: role of temperature, RBC, platelets, and plasma clotting proteins” [2]. This monograph reports the role of red blood cell function to exert a hemostatic effect together with the platelet hemostatic function of fresh, liquid-preserved, and dimethyl sulfoxide (DMSO)–cryopreserved platelets to reduce the bleeding time and non...
Source: Transfusion Medicine Reviews - March 26, 2015 Category: Hematology Authors: C. Robert Valeri, Gina Ragno Giorgio Tags: Letter to the Editor Source Type: research
The Epidemiology of Imported Malaria and Transfusion Policy in 5 Nonendemic Countries
Addressing risk of imported malaria is complicated by 5 human species of Plasmodium, semi-immunity in donors with long-term exposure, increasing travel and immigration, changing risk in endemic areas, and limitations of screening assays. To gain insight into policy formulation, we have compiled epidemiologic data from 5 countries with different policies involving either deferral (the United States and Canada) or selective testing (France, England, and Australia). The greatest risk is from semi-immune former residents of endemic areas, but the greatest impact on sufficiency (donor loss) is from low-risk short-term travel. (...
Source: Transfusion Medicine Reviews - March 26, 2015 Category: Hematology Authors: Sheila F. O’Brien, Gilles Delage, Clive R. Seed, Josiane Pillonel, Cécile C. Fabra, Katy Davison, Alan Kitchen, Whitney R. Steele, David A. Leiby Source Type: research
Plasma and Plasma Protein Product Transfusion: A Canadian Blood Services Centre for Innovation Symposium
Plasma obtained via whole blood donation processing or via apheresis technology can either be transfused directly to patients, or pooled and fractionated into plasma protein products that are concentrates of one or more purified plasma protein. The evidence base supporting clinical efficacy in most of the indications for which plasma is transfused is weak, while high quality evidence supports the efficacy of plasma protein products in at least some of the clinical settings in which they are used. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 26, 2015 Category: Hematology Authors: Michelle P. Zeller, Khalid S. Al Habsi, Mia Golder, Geraldine M. Walsh, William P. Sheffield Source Type: research
The epidemiology of imported malaria and transfusion policy in five non-endemic countries
Addressing risk of imported malaria is complicated by five human species of Plasmodium, semi-immunity in donors with long-term exposure, increasing travel and immigration, changing risk in endemic areas and limitations of screening assays. To gain insight into policy formulation we have compiled epidemiologic data from five countries with different policies involving either deferral (the USA and Canada) or selective testing (France, England and Australia). The greatest risk is from semi-immune former residents of endemic areas but the greatest impact on sufficiency (donor loss) is from low-risk short-term travel. (Source: ...
Source: Transfusion Medicine Reviews - March 26, 2015 Category: Hematology Authors: Sheila F. O’Brien, Gilles Delage, Clive R. Seed, Josiane Pillonel, Cécile C. Fabra, Katy Davison, Alan Kitchen, Whitney R. Steele, David A. Leiby Source Type: research
Response to the paper on DMSO cryopreserved platelets published in Transfusion Medicine Reviews Volume 28(4)
We were interested in Slichter et al.'s “Review of in vivo studies of dimethyl sulfoxide cryopreserved platelets” (1) and would like to draw attention to our work in this field which is described in the monograph “Non-surgical bleeding diathesis in anemic thrombocytopenic patients: role of temperature, RBC, platelets, and plasma clotting proteins” (2). This monograph reports the role of red blood cell function to exert a hemostatic effect together with the platelet hemostatic function of fresh, liquid preserved, and dimethyl sulfoxide (DMSO) cryopreserved platelets to reduce the bleeding time and nonsurgical blood ...
Source: Transfusion Medicine Reviews - March 26, 2015 Category: Hematology Authors: C. Robert Valeri, Gina Ragno Giorgio Tags: Letter to the Editor Source Type: research
Blood warming and hemolysis: a systematic review with meta-analysis
The use of fluid warmers during blood transfusion is recommended to avoid inducing hypothermia and its harmful effects. Fluid warmers offered by manufacturers can reach temperatures of 43°C. However, the recommendations of national regulatory organizations do not clearly indicate the maximum heating temperature in relation to the risk of hemolysis. To fill this gap, we conducted a systematic review of the literature with meta-analysis. To match clinical practice, this review was limited to fluid warmers that used contact heating; thus, studies that used radiofrequency or microwave heating were excluded. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 25, 2015 Category: Hematology Authors: Thomas G. Poder, Wendyam Gérard Nonkani, Élyonore Tsakeu Leponkouo Source Type: research
Keeping Blood Transfusion Safe From West Nile Virus: American Red Cross Experience, 2003 to 2012
West Nile virus (WNV) appeared for the first time in the United States in 1999 and rapidly spread across the Western hemisphere within a few years causing hundreds of thousands of human infections and significant disease. In 2002, it was found to be transmissible by blood transfusion, and within less than a year, nucleic acid testing for WNV RNA was in place for all US donations. The American Red Cross (ARC) collects approximately 40% of blood donations in the United States and closely monitors the results of such testing and evaluates donors found to be reactive. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 24, 2015 Category: Hematology Authors: Roger Y. Dodd, Gregory A. Foster, Susan L. Stramer Source Type: research
Keeping blood transfusion safe from West Nile virus: American Red Cross experience, 2003-2012
West Nile virus (WNV) appeared for the first time in the United States in 1999 and rapidly spread across the Western hemisphere within a few years causing hundreds of thousands of human infections and significant disease. In 2002, it was found to be transmissible by blood transfusion and within less than a year, nucleic acid testing for WNV RNA was in place for all US donations. The American Red Cross (ARC) collects about 40% of blood donations in the US and closely monitors the results of such testing and evaluates donors found to be reactive. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 24, 2015 Category: Hematology Authors: Roger Y. Dodd, Gregory A. Foster, Susan L. Stramer Source Type: research
Journal Club
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 2, 2015 Category: Hematology Authors: Richard Haspel, Simon Stanworth, Jeannie Callum Source Type: research
Transfusion Medicine Reviews Special Edition: Focus on Australia
In this issue of Transfusion Medicine Reviews we are pleased to introduce a new feature in which we focus on research and practice in transfusion medicine from one region of the world. This special edition presents manuscripts by authors from Australia. In preparing the first of these special editions, Drs Erica Wood and Amanda Davis (Melbourne) served as Guest Editors and we are very grateful to them and the authors throughout Australia who contributed their work. We hope this Focus On Australia will allow readers to get a better understanding of the Australian perspective on current topics in Transfusion Medicine and tha...
Source: Transfusion Medicine Reviews - February 19, 2015 Category: Hematology Authors: Sunny Dzik, Michael F. Murphy Source Type: research
Transfusion Medicine in Australia
We are honored to be Guest Editors for this special issue of Transfusion Medicine Reviews devoted to transfusion medicine in Australia. When asked to lead this issue, we realized we would not be able to include contributions from all of the many talented and dedicated Australian clinicians and researchers working in transfusion. In this regard, we chose to focus on clinical aspects of transfusion medicine and we hope we have provided an interesting spectrum of material. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - February 19, 2015 Category: Hematology Authors: Amanda K. Davis, Erica M. Wood Source Type: research
Transfusion Medicine in sub-Saharan Africa: Conference Summary
In November 2014, a three day conference devoted to Transfusion Medicine in sub-Saharan Africa was held in Kampala, Uganda. Faculty from academic institutions in Uganda provided a broad overview of issues pertinent to transfusion medicine in Africa. The conference consisted of lectures, demonstrations, and discussions followed by five small-group workshops held at the Uganda Blood Transfusion Service Laboratories, the Ugandan Cancer Institute, and the Mulago National Referral Hospital. Highlighted topics included: the challenges posed by increasing clinical demands for blood; the need for better patient identification at t...
Source: Transfusion Medicine Reviews - February 19, 2015 Category: Hematology Authors: Walter ‘Sunny’ Dzik, Dorothy Kyeyune, Grace Otekat, Bernard Natukunda, Heather Hume, Phillip G. Kasirye, Henry Ddungu, Isaac Kajja, Aggrey Dhabangi, Godfrey R. Mugyenyi, Claire Seguin, Linda Barnes, Meghan Delaney Source Type: research
Platelets Are Not Just for Clots
Although the role of platelets as central mediators of hemostasis and thrombosis has been the primary focus of research into platelet biology for more than a century, over the last decade, nonhemostatic functions of platelets have been increasingly defined. As such, a large body of experimental evidence now exists, which places the platelet as a key player in mediating a diverse range of immune, inflammatory, and malignant disease processes. This review outlines the central mechanisms that underpin the nonhemostatic role of platelets and provides a summary of evidence demonstrating a role for platelets in mediating selecte...
Source: Transfusion Medicine Reviews - February 10, 2015 Category: Hematology Authors: James D. McFadyen, Zane S. Kaplan Source Type: research
Transfusion Interventions in Critical Bleeding Requiring Massive Transfusion: a Systematic Review
Critical bleeding (CB) requiring massive transfusion (MT) can occur in a variety of clinical contexts, and is associated with substantial mortality and morbidity. In 2011, the Australian National Blood Authority (NBA) published patient blood management (PBM) guidelines for critical bleeding and massive transfusion, which found limited high-quality evidence from which only two recommendations could be made. The aim of this systematic review (SR) was to update these guidelines and identify evidence gaps still to be addressed. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - February 5, 2015 Category: Hematology Authors: Zoe K. McQuilten, Gemma Crighton, Sunelle Engelbrecht, Robert Gotmaker, Susan J. Brunskill, Michael F. Murphy, Erica M. Wood Source Type: research
