Recognition and management of hemostatic disorders in critically ill patients needing to undergo an invasive procedure
Abnormal laboratory coagulation tests are frequently documented in critically ill patients, and these patients often also need to undergo invasive procedures. Clinicians have an understandable desire to minimize any perceived heightened risk of bleeding complications in those patients who require invasive procedures. In this setting prophylactic administration of platelets or plasma is commonplace. This review explores the nature of these sequential statements, and the degree to which these statements are supported by evidence. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - June 14, 2017 Category: Hematology Authors: Marcella C.A. M üller, S.J. Stanworth, M. Coppens, N.P. Juffermans Source Type: research
Journal Club
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - May 18, 2017 Category: Hematology Authors: Richard Haspel, Simon Stanworth, Jeannie Callum Source Type: research
Emerging Infectious Diseases and Blood Safety: Modeling the Transfusion-Transmission Risk
While the transfusion-transmission (TT) risk associated with the major transfusion-relevant viruses such as HIV is now very low, during the last 20 years there has been a growing awareness of the threat to blood safety from emerging infectious diseases, a number of which are known to be, or are potentially, transfusion transmissible. Two published models for estimating the transfusion-transmission risk from EIDs, referred to as the Biggerstaff-Petersen model and the European Upfront Risk Assessment Tool (EUFRAT), respectively, have been applied to several EIDs in outbreak situations. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - May 15, 2017 Category: Hematology Authors: Philip Kiely, Manoj Gambhir, Allen C Cheng, Zoe K McQuilten, Clive R Seed, Erica M Wood Source Type: research
Emerging infectious diseases and blood safety: modelling the transfusion-transmission risk
While the transfusion-transmission risk associated with the major transfusion-relevant viruses such as HIV is now very low, during the last 20years there has been a growing awareness of the threat to blood safety from emerging infectious diseases, a number of which are known to be, or are potentially, transfusion transmissible. Two published models for estimating the transfusion-transmission risk from EIDs, referred to as the Biggerstaff-Petersen model and the European Upfront Risk Assessment Tool (EUFRAT), respectively, have been applied to several EIDs in outbreak situations. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - May 15, 2017 Category: Hematology Authors: Philip Kiely, Manoj Gambhir, Allen C Cheng, Zoe K McQuilten, Clive R Seed, Erica M Wood Source Type: research
Management of platelet disorders and platelet transfusions in ICU patients
Thrombocytopenia or receipt of anti-platelet drugs, with or without bleeding, are common indications for platelet transfusions in the ICU. However there is almost no evidence base for these practices other than expert opinion. Also common is use of platelet transfusions prior to invasive procedures or surgery in patients with thrombocytopenia. Likewise there is no high quality evidence that such practices are efficacious or safe. Recently, it has become clear that, whether causal or not, patients receiving prophylactic platelet transfusions experience high rates of nosocomial infection, thrombosis, organ failure and mortal...
Source: Transfusion Medicine Reviews - May 3, 2017 Category: Hematology Authors: Neil Blumberg, Jill M. Cholette, Amy E. Schmidt, Richard P. Phipps, Sherry L. Spinelli, Joanna M. Heal, Anthony P. Pietropaoli, Majed A. Refaai, Patricia J. Sime Source Type: research
Adjuncts to blood component therapies for the treatment of bleeding in the intensive care unit
Patients who are critically ill following surgical or traumatic injury often present with coagulopathy as a component of the complex multi-system dysfunction that clinicians must rapidly diagnose and treat in the intensive care environment. Failure to recognize coagulopathy while volume resuscitation with crystalloid or colloid takes place, or an unbalanced transfusion strategy focused on packed red blood cell transfusion, can all significantly worsen coagulopathy leading to increased transfusion requirements and poor outcomes. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - April 25, 2017 Category: Hematology Authors: Jerrold H. Levy, Kamrouz Ghadimi, Quintin J. Quinones, Raquel R. Bartz, Ian Welsby Source Type: research
Masthead
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 26, 2017 Category: Hematology Source Type: research
Title Page
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 26, 2017 Category: Hematology Source Type: research
Editorial Board
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 26, 2017 Category: Hematology Source Type: research
Contents
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 26, 2017 Category: Hematology Source Type: research
Aims and Scope
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 26, 2017 Category: Hematology Source Type: research
The safety and efficacy of lysine analogues in cancer patients: A systematic review and meta-analysis
The objective of our review is to investigate safety and efficacy of lysine analogue administration in the patients with cancer. Medline, Embase, and The Cochrane Library were searched from inception to June, 2016. Reference lists of retrieved studies were searched to identify additional publications. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 22, 2017 Category: Hematology Authors: Joshua Montroy, Nicholas A Fergusson, Brian Hutton, Luke T Lavall ée, Chris Morash, Ilias Cagiannos, Sonya Cnossen, Dean A Fergusson, Rodney H Breau Source Type: research
Intersecting Worlds of Transfusion and Transplantation Medicine: An International Symposium organized by the Canadian Blood Services Centre for Innovation
The principal theme of the symposium was centred on how the world of regenerative medicine intersects with that of transfusion medicine, with a particular focus on hematopoietic stem cells (HSCs) and stem cell therapies. The symposium highlighted several exciting developments and identified areas where additional research is needed. A revised map of human hematopoietic hierarchy was presented based on the functional and phenotypic analysis of thousands of single stem and progenitor cells from adult bone marrow and fetal liver. (Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - March 21, 2017 Category: Hematology Authors: Kendra M. Hodgkinson, Jeffrey Kiernan, Andrew W. Shih, Ziad Solh, William P. Sheffield, Nicolas Pineault Source Type: research
Journal Club
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - February 13, 2017 Category: Hematology Authors: Simon Stanworth, Richard Haspel, Jeannie Callum Source Type: research
Masthead
(Source: Transfusion Medicine Reviews)
Source: Transfusion Medicine Reviews - December 29, 2016 Category: Hematology Source Type: research
