Adjuncts to blood component therapies for the treatment of bleeding in the intensive care unit

Patients who are critically ill following surgical or traumatic injury often present with coagulopathy as a component of the complex multi-system dysfunction that clinicians must rapidly diagnose and treat in the intensive care environment. Failure to recognize coagulopathy while volume resuscitation with crystalloid or colloid takes place, or an unbalanced transfusion strategy focused on packed red blood cell transfusion, can all significantly worsen coagulopathy leading to increased transfusion requirements and poor outcomes.

Source: Transfusion Medicine Reviews - April 25, 2017 Category: Hematology Authors: Jerrold H. Levy, Kamrouz Ghadimi, Quintin J. Quinones, Raquel R. Bartz, Ian Welsby Source Type: research