Transfusion Interventions in Critical Bleeding Requiring Massive Transfusion: a Systematic Review

Critical bleeding (CB) requiring massive transfusion (MT) can occur in a variety of clinical contexts, and is associated with substantial mortality and morbidity. In 2011, the Australian National Blood Authority (NBA) published patient blood management (PBM) guidelines for critical bleeding and massive transfusion, which found limited high-quality evidence from which only two recommendations could be made. The aim of this systematic review (SR) was to update these guidelines and identify evidence gaps still to be addressed.

Source: Transfusion Medicine Reviews - February 5, 2015 Category: Hematology Authors: Zoe K. McQuilten, Gemma Crighton, Sunelle Engelbrecht, Robert Gotmaker, Susan J. Brunskill, Michael F. Murphy, Erica M. Wood Source Type: research