Understanding the microscopic binding mechanism of hydroxylated and sulfated polybrominated diphenyl ethers with transthyretin by molecular docking, molecular dynamics simulations and binding free energy calculations
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00638H, PaperHuiming Cao, Yuzhen Sun, Ling Wang, Chunyan Zhao, Jianjie Fu, Aiqian Zhang The binding of TTR with sulfated-PBDEs and OH-PBDEs shows different molecular recognition mechanisms. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 20, 2017 Category: Molecular Biology Authors: Huiming Cao Source Type: research
EnhancerPred2.0: predicting enhancers and their strength based on position-specific trinucleotide propensity and electron-ion interaction potential feature selection
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00054E, Paperwenying He, Cangzhi Jia Enhancers are cis-acting elements that play major roles in upregulating eukaryotic gene expression by providing binding sites for transcription factors and their complexes. Because enhancers are highly cell/tissue specific, lack... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 20, 2017 Category: Molecular Biology Authors: wenying He Source Type: research
DNA Condensation in Live E. Coli Provides Evidence for Transertion
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00753H, CommunicationAnil Kumar Gorle, Amy L Bottomley, Elizabeth Harry, John Grant Collins, Frank Richard Keene, Clifford Edwin Woodward Condensation studies of chromosomal DNA inE. coli with a tetranuclear ruthenium complex are carried out and images obtained with wide-field fluorescence microscopy. Remarkably different condensate morphologies resulted, depending upon... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 20, 2017 Category: Molecular Biology Authors: Anil Kumar Gorle Source Type: research
Consensus architecture of promoters and transcription units in Escherichia coli: design principles for synthetic biology
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00789A, Review ArticleCynthia Paola Rangel, Edgardo Galan, Agustino Martinez Genetic information in genomes is ordered, arranged in such a way that it constitutes a code, the so-called cis regulatory code. The regulatory machinery of the cell, termed trans-factors, decodes... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 18, 2017 Category: Molecular Biology Authors: Cynthia Paola Rangel Source Type: research
Construction and simulation of the Bradyrhizobium diazoefficiens USDA110 metabolic network: a comparison between free-living and symbiotic states
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00553E, PaperYi Yang, Xiao-Pan Hu, Bin-Guang Ma The first genome-scale metabolic network forBradyrhizobium was constructed and the metabolic properties were compared between the free-living and symbiotic physiological states. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 13, 2017 Category: Molecular Biology Authors: Yi Yang Source Type: research
Molecular Dynamics Investigations of Membrane-Bound CYP2C19 Polymorphisms Reveal Distinct Mechanisms for Peripheral Variants by Long-Range Effects on the Enzymatic Activity
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00827E, PaperYing-Lu Cui, Rong-Ling Wu Increasing sophistication in methods used to account for human polymorphisms in susceptibility to drug metabolism has been one of the success stories in the prevention of adverse drug reaction. Genetic... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 9, 2017 Category: Molecular Biology Authors: Ying-Lu Cui Source Type: research
Mass Spectrometry for the Discovery of Biomarkers of Sepsis
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00656F, Review ArticleKatelyn Ludwig, Amanda Hummon Sepsis is a serious medical condition that occurs in 30% of patients in intensive care units (ICUs). Early detection of sepsis is key to prevent its progression to severe sepsis... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 8, 2017 Category: Molecular Biology Authors: Katelyn Ludwig Source Type: research
Understanding microscopic binding mechanism of hydroxylated and sulfated polybrominated diphenyl ethers with transthyretin by molecular docking, molecular dynamics simulations and binding free energy calculations
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00638H, PaperHuiming Cao, Yuzhen Sun, Ling Wang, Chunyan Zhao, Jianjie Fu, Aiqian Zhang Polybrominated diphenyl ethers (PBDEs), one typical type of persistent environmental contaminants, have toxicological effect as disrupting thyroid homeostasis in human body. The high binding affinities of hydroxylated metabolites of PBDEs... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 8, 2017 Category: Molecular Biology Authors: Huiming Cao Source Type: research
Urinary Metabolic Signatures and Early Triage of Acute Radiation Exposure in Rat Model
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00785F, PaperMingxiao Zhao, King-Tong Lau, Xian Zhou, Jian Fang Wu, Jun Yang, Chang Wang After a large-scale radiological accident, early-response biomarkers to assess radiation exposure over a broad dose range are not only the basis of rapid radiation triage, but also the key to... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 8, 2017 Category: Molecular Biology Authors: Mingxiao Zhao Source Type: research
Non-active site mutations disturb the loop dynamics, dimerization, viral budding and egress of VP40 of the Ebola virus
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00803H, PaperMarissa Balmith, Mahmoud E. S. Soliman The first account of the dynamic features of the loop region of VP40 of the Ebola virus (EboV) using accelerated molecular dynamics (aMD) simulations is reported herein. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 8, 2017 Category: Molecular Biology Authors: Marissa Balmith Source Type: research
Predicting Brain Network Changes in Alzheimer's Disease with Link Prediction Algorithms
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00815A, PaperSadegh sulaimany, Mohammad Khansari, Peyman Zarrineh, Madeline Daianu, Neda Jahanshad, Paul Thompson, Ali Masoudi-Nejad Link prediction is a promising research area for modeling various types of networks and has mainly focused on predicting missing links. Link prediction methods may be valuable for describing brain... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 8, 2017 Category: Molecular Biology Authors: Sadegh sulaimany Source Type: research
Protein Subcellular Localization Prediction Using Multiple Kernel Learning Based Support Vector Machine
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00860G, PaperMd. Al Mehedi Hasan, Shamim Ahmad, Md. Khademul Islam Molla Prediction of subcellular locations of proteins can provide useful hints for revealing their functions as well as for understanding the mechanisms of some diseases and finally for developing novel drugs.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 3, 2017 Category: Molecular Biology Authors: Md. Al Mehedi Hasan Source Type: research
Designing an efficient multi-epitope oral vaccine against Helicobacter pylori using immunoinformatics and structural vaccinology approaches
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00772D, PaperNavid Nezafat, Mahboobeh Eslami, Manica Negahdaripour, Mohammad Reza Rahbar, Younes Ghasemi Helicobacter pylori is the cunning bacterium that can live in the stomach of a large number of people without any symptoms, but gradually can be led to gastric cancer. Due... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 3, 2017 Category: Molecular Biology Authors: Navid Nezafat Source Type: research
Gene essentiality prediction based on fractal features and machine learning
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00806B, PaperYongming Yu, Licai Yang, Zhiping Liu, Chuansheng Zhu Predicting bacterial essential genes using only fractal features. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 1, 2017 Category: Molecular Biology Authors: Yongming Yu Source Type: research
Phenylephrine-induced cardiac hypertrophy is attenuated by a histone acetylase inhibitor anacardic acid in mice
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00692B, PaperChang PENG, Xiao-mei LUO, Shuo LI, Huichao SUN Cardiac hypertrophy is a complex process involving highly coordinated but tightly regulation of multiple elements, such as epigenetics which make an important contribution to myocardium remodeling and cardiac hypertrophy. Epigenetic... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - February 1, 2017 Category: Molecular Biology Authors: Chang PENG Source Type: research
