Model studies of the effects of intracellular crowding on nucleic acid interactions
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00654J, Review ArticleShu-ichi Nakano, Naoki Sugimoto Studies using experimental model systems have revealed significant effects of the intracellular environment on the interactions of DNA and RNA. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - December 1, 2016 Category: Molecular Biology Authors: Shu-ichi Nakano Source Type: research

Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics
We reported the proteome-wide profiling of cellular targets of celastrol in HeLa cellsvia competitive chemoproteomics approach utilizing a cysteine-targeting activity-based probe. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - December 1, 2016 Category: Molecular Biology Authors: Yiqing Zhou Source Type: research

Proteomics profiling of interactome dynamics by colocalisation analysis (COLA)
This article is licensed under aCreative Commons Attribution-NonCommercial 3.0 Unported Licence.Faraz K. Mardakheh, Heba Z. Sailem, Sandra Kumper, Christopher J. Tape, Ryan R. McCully, Angela Paul, Sara Anjomani-Virmouni, Claus Jorgensen, George Poulogiannis, Christopher J. Marshall, Chris Bakal A combined proteomics and bioinformatics strategy for mapping interactome dynamicsvia assessment of subcellular protein-protein colocalisations. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - December 1, 2016 Category: Molecular Biology Authors: Faraz K. Mardakheh Source Type: research

Biological applications of xeno nucleic acids
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00538A, Review ArticleKunihiko Morihiro, Yuuya Kasahara, Satoshi Obika Xeno nucleic acids (XNAs) are a group of chemically modified nucleic acid analogues that have been applied to various biological technologies such as antisense oligonucleotides, siRNAs and aptamers. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - December 1, 2016 Category: Molecular Biology Authors: Kunihiko Morihiro Source Type: research

The development of small-molecule modulators for ClpP protease activity
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00644B, Review ArticleFei Ye, Jiahui Li, Cai-Guang Yang Deregulating ClpP activity either through inhibition or overactivation could lead to antibacterial activity. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - December 1, 2016 Category: Molecular Biology Authors: Fei Ye Source Type: research