Construction and Simulation of Bradyrhizobium diazoefficiens USDA110 Metabolic Network: Comparison between the Free-living and Symbiotic States
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00553E, PaperYi Yang, Xiao-Pan Hu, Bin-Guang Ma Bradyrhizobium diazoefficiens is a rhizobium able to convert atmospheric nitrogen into ammonium by establishing mutualistic symbiosis with soybean. It has been recognized as an important parent strain for microbial agents... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 31, 2017 Category: Molecular Biology Authors: Yi Yang Source Type: research

Elucidating the biosynthetic pathways of volatile organic compounds in Mycobacterium tuberculosis through a computational approach
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00796A, PaperPurva Bhatter, Karthik Raman, Vani Janakiraman Microbial volatile organic compounds (VOCs) have gained prominence in the recent past for their potential use as disease markers. The discovery of microbial VOCs has benefitted 'difficult to detect' diseases... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 30, 2017 Category: Molecular Biology Authors: Purva Bhatter Source Type: research

Integrating Multiple Omics Data for Discovery of Potential Beclin-1 Interactors in Breast Cancer
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00653A, PaperYi Chen, Xuan Wang, Guan Wang, Zhaozhi Li, Jinjin Wang, Lingyu Huang, Ziyi Qin, Xiang Yuan, Zhong Cheng, Shu Zhang, Yiqiong Yin, Jun He Breast Cancer has been reported as one of the most frequently diagnosed malignant diseases and the leading cause of cancer death in women all around the world. Besides, this complicated... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 28, 2017 Category: Molecular Biology Authors: Yi Chen Source Type: research

Effect of flexible linker length on the activity of fusion protein 4-coumaroyl-CoA ligase::stilbene synthase
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00563B, PaperHuili Guo, Yadong Yang, Feiyan Xue, Hong Zhang, Tiran Huang, Wenbin Liu, Huan Liu, Fenqiang Zhang, Mingfeng Yang, Chunmei Liu, Heshu Lu, Yansheng Zhang, Lanqing Ma In order to elucidate the effect of flexible linker length on the catalytic efficiency of fusion protein, two short flexible peptide linkers of various length were fused betweenArabidopsis thaliana... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 24, 2017 Category: Molecular Biology Authors: Huili Guo Source Type: research

Soluble epoxide hydrolase inhibitors might prevent ischemic arrhythmias via microRNA-1 repression in primary neonatal mouse ventricular myocytes
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00824K, PaperQiong Liu, Xuan Zhao, Ran Peng, Mi Wang, Wang Zhao, Ya-jun Gui, Cai-xiu Liao, Dan-yan Xu Ischemic arrhythmias are the main causes of sudden cardiac death. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 23, 2017 Category: Molecular Biology Authors: Qiong Liu Source Type: research

Super RLuc8-sFv; a new luciferase-labeled probe for detection of human CD4+ cells
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00652C, CommunicationA. Safavi, R. Emamzadeh, M. Nazari, M. Ehsani, S. H. Zarkesh-Esfahani, S. Rahgozar A probe has been designed, produced and assayed for the detection of T-helper cells. The sFv fragment fused to the C-terminus of superRenilla luciferase 8 (Super RLuc8) and the probe successfully used for detection of human CD4+ cells using luminometer. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 23, 2017 Category: Molecular Biology Authors: A. Safavi Source Type: research

Crosstalk between the nucleolus and the DNA damage response
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00740F, Review ArticleL. M. Ogawa, S. J. Baserga We review the role for conventional DNA repair proteins in ribosome biogenesis and ribosome biogenesis factors in DNA repair. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 23, 2017 Category: Molecular Biology Authors: L. M. Ogawa Source Type: research

A systems approach for the elucidation of crucial genes and network constituents of cervical intraepithelial neoplasia 1 (CIN1)
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00615A, PaperShikha Suman, Ashutosh Mishra, Anurag Kulshrestha Network based approach for finding biomarkers for predicting the clinical behavior of cervical neoplasia cells at its earliest onset. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 19, 2017 Category: Molecular Biology Authors: Shikha Suman Source Type: research

Identification of novel inhibitors of the translationally controlled tumor protein (TCTP): insights from molecular dynamics
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00850J, PaperRakesh Kumar, Ranjana Maurya, shweta saran Translationally controlled tumor protein (TCTP) is a highly conserved multifunctional protein, preferentially expressed in mitotically active tissues and is a potential biomarker and therapeutic target for lung cancers. An understanding... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 19, 2017 Category: Molecular Biology Authors: Rakesh Kumar Source Type: research

Solid Support Resins and Affinity Purification Mass Spectrometry
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00735J, Review ArticleSpencer Havis, Wilna J Moree, Sujina Mali, Steven J Bark Co-affinity purification-mass spectrometry (CoAP-MS) is a primary technology for elucidating the protein-protein interactions that form the basis of all biological processes. A critical component of CoAP-MS is the affinity purification... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 19, 2017 Category: Molecular Biology Authors: Spencer Havis Source Type: research

Regulation of Lipids is Central to Replicative Senescence
In this study, we comparatively investigated the global lipid profiles and... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 19, 2017 Category: Molecular Biology Authors: Darleny Y Lizardo Source Type: research

Correction: Elucidating time-dependent changes in the urinary metabolome of renal transplant patients by a combined 1H NMR and GC-MS approach
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Kienana Muhrez, Lydie Nadal-Desbarats, Jean-Michel Halimi, Binta Dieme, Matthias Buchler, Patrick Emond, Helene Blasco, Chantal Le Guellec To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 19, 2017 Category: Molecular Biology Authors: Kienana Muhrez Source Type: research

The in silico identification of human bile salt export pump (ABCB11) inhibitors associated with cholestatic drug-induced liver injury
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00744A, PaperLili Xi, Jia Yao, Yuhui Wei, Xin'an Wu, Xiaojun Yao, Huanxiang Liu, Shuyan Li The RF and pharmacophore models can be considered as integrated screening tools to indicate the potential risk of cholestatic DILI. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 16, 2017 Category: Molecular Biology Authors: Lili Xi Source Type: research

Exploration and analysis of drug modes of action through feature integration
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C6MB00635C, PaperMingyuan Xin, Jun Fan, Mingyao Liu, Zhenran Jiang Identifying drug modes of action (MoA) is of paramount importance for having a good grasp of drug indications in clinical tests. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 16, 2017 Category: Molecular Biology Authors: Mingyuan Xin Source Type: research

Small RNA sequencing revealed dysregulated piRNAs in Alzheimer's disease and their probable role in pathogenesis
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00699J, PaperJyoti Roy, Arijita Sarkar, Sibun Parida, Zhumur Ghosh, Bibekanand Mallick PIWI-interacting (piRNAs), ~23-36 nucleotide-long small non-coding RNAs, earlier believed to be germline-specific, has now been identified in somatic cells including neural cells. However, piRNAs have not yet been studied in... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - January 16, 2017 Category: Molecular Biology Authors: Jyoti Roy Source Type: research