CarSite: identifying carbonylated sites of human proteins based on a one-sided selection resampling method
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C7MB00363C, PaperYun Zuo, Cang-Zhi Jia Protein carbonylation is one of the most important biomarkers of oxidative protein damage and such protein damage is linked to various diseases and aging. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 22, 2017 Category: Molecular Biology Authors: Yun Zuo Source Type: research
A Computational Method Using Differential Gene Expression to Predict Altered Metabolism of Multicellular Organisms
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00462A, PaperLvxing Zhu, Haoran Zheng, Xinying Hu, Xu Yang Altered metabolism is often identified as a cause or an effect of physiology and pathogenesis. But it is difficult to predict the metabolic flux distributions of multicellular organisms due to... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 22, 2017 Category: Molecular Biology Authors: Lvxing Zhu Source Type: research
Lipidomic alterations of in vitro macrophage infection by L. infantum and L. amazonensis
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00381A, PaperFernanda Negrao, Daniel Ruiz Abanades, Carol Jaegger Franco, Daniele Fernanda de Oliveira Rocha, Katia Roberta A. Belaz, Selma Giorgio, Marcos N Eberlin, Celio Fernando Figueiredo Angolini Particular lipid profiles have been found in two different protozoa of the Leishmania genus. Leishmania infantum, a visceral leishmaniasis causative agent and Leishmania amazonensis, a cutaneous leishmaniasis, reveal distinctive lipid... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 20, 2017 Category: Molecular Biology Authors: Fernanda Negrao Source Type: research
Role of solvent properties of water in crowding effects induced by macromolecular agents and osmolytes
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00436B, PaperLuisa A Ferreira, Vladimir N. Uversky, Boris Y Zaslavsky Solvent properties of water in aqueous solutions of polyethylene glycols of various molecular weights, L-proline, betaine, and a series of chlorides of varied concentrations are assayed using three solvatochromic dyes.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 20, 2017 Category: Molecular Biology Authors: Luisa A Ferreira Source Type: research
Evaluation and optimization of reduction and alkylation methods to maximize peptide identification with MS-based proteomics
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00393E, PaperSuttipong Suttapitugsakul, Haopeng Xiao, Johanna M Smeekens, Ronghu Wu Mass spectrometry (MS) has become an increasingly important technique to analyze proteins. In popular bottom-up MS-based proteomics, reduction and alkylation are routine steps to facilitate peptide identification. However, the reaction... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 20, 2017 Category: Molecular Biology Authors: Suttipong Suttapitugsakul Source Type: research
Computational identification of protein S-sulfenylation sites by incorporating the multiple sequence features information
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00491E, PaperMd. Mehedi Hasan, Dianjing Guo, Hiroyuki Kurata Cysteine S-sulfenylation is a major type of posttranslational modification that contributes to protein structure and function regulation in many cellular processes. Experimental identification of S-sulfenylation sites is challenging, due to... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 18, 2017 Category: Molecular Biology Authors: Md. Mehedi Hasan Source Type: research
A novel method for identifying potential disease-related miRNAs via a disease-miRNA-target heterogeneous network
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C7MB00485K, PaperLiang Ding, Minghui Wang, Dongdong Sun, Ao Li MicroRNAs (miRNAs), as a kind of important small endogenous single-stranded non-coding RNA, play critical roles in a large number of human diseases. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 18, 2017 Category: Molecular Biology Authors: Liang Ding Source Type: research
HIV/HAART-associated oxidative stress is detectable by metabonomics
Mol. BioSyst., 2017, Advance Article DOI: 10.1039/C7MB00336F, Review ArticleAurelia A. Williams, Lungile J. Sitole, Debra Meyer HIV and/or its treatment increases reactive oxidant species and concomitantly decreases antioxidants, collectively destabilizing DNA, protein and lipids, producing markers of oxidative stress, detectable by metabonomics. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 18, 2017 Category: Molecular Biology Authors: Aurelia A. Williams Source Type: research
Modelling the Propagation of a Dynamical Signature in Gene Expression Mediated by the Transport of Extracellular MicroRNAs
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00509A, PaperAlexis Grau Ribes, Yannick De Decker, Claude Gerard, Laurence Rongy Extracellular microRNAs (miRNAs) carried by exosomes can play a key role in cell-to-cell communication. Deregulation of miRNA expression and exosomes secretion have been related to pathological conditions such as cancer.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 18, 2017 Category: Molecular Biology Authors: Alexis Grau Ribes Source Type: research
Metabolomics reveal mitochondrial and fatty acid metabolism disorders contribute to the development of DKD in T2DM patients
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00167C, PaperLing Li, Chengshi Wang, Hongliu Yang, Shuyun Liu, Yanrong Lu, Ping Fu, Jingping Liu Diabetic kidney disease (DKD) is the leading cause of ESRD, while early intervention shows great benefit to prevent the progression of DKD, so sensitive biomarkers for DKD are still desired.... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 14, 2017 Category: Molecular Biology Authors: Ling Li Source Type: research
Imperfect crowding adaptation of mammalian cells towards osmotic stress and its modulation by osmolytes
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00432J, CommunicationDavid Gnutt, Oliver Brylski, Eugen Edengeiser, Martina Havenith, Simon Ebbinghaus Changes of the extracellular milieu could affect cellular crowding. To prevent detrimental effects, cells use adaptation mechanisms to react to such conditions. Using fluorescent crowding sensors, we show that the... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 14, 2017 Category: Molecular Biology Authors: David Gnutt Source Type: research
Screening for Concanavalin A Binders from a Mannose-Modified [small alpha]-Helix Peptide Phage Library
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00495H, CommunicationIou Ven Chang, Hiroshi Tsutsumi, Hisakazu Mihara Mannose-modified lectin-binding peptides were obtained from an [small alpha]-helical-designed peptide phage library. Concanavalin A (ConA) was used as a representative target protein for the lectin family. The identified glycopeptides could selectively... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 13, 2017 Category: Molecular Biology Authors: Iou Ven Chang Source Type: research
Network-based modelling and percolation analysis of conformational dynamics and activation in the CDK2 and CDK4 proteins: Dynamic and energetic polarization of the kinase lobes may determine divergence of the regulatory mechanisms
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00355B, PaperGennady M Verkhivker The overarching goal of delineating molecular principles underlying differentiation of the activation mechanisms in cyclin-depedent kinases (CDKs) is important for understanding regulatory divergences among closely related kinases which can be... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 13, 2017 Category: Molecular Biology Authors: Gennady M Verkhivker Source Type: research
Identification of suitable promoter for sigma factor of Mycobacterium tuberculosis
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00317J, PaperAayatti Mallick Gupta, Sanchita Mukherjee, Arkajyoti Dutta, Jayanta Mukhopadhyay, Dhananjay Bhattacharyya, Sukhendu Mandal The promoter binding specificity is one of the important characters of transcription by Mycobacterium tuberculosis (Mtb) sigma ([sigma]) factors, which remains unexplored due to limited structural evidences. Our previous study... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 13, 2017 Category: Molecular Biology Authors: Aayatti Mallick Gupta Source Type: research
Gene co-opening network deciphers gene functional relationships
Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C7MB00430C, PaperWenran Li, Meng Wang, Jinghao Sun, Yong Wang, Rui Jiang Genome sequencing technology has generated a vast amount of genomic and epigenomic data, and has provided us a great opportunity to study gene functions on a global scale from an... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - Molecular Biosystems)
Source: RSC - Molecular Biosystems - September 13, 2017 Category: Molecular Biology Authors: Wenran Li Source Type: research
