Molecular Dynamics Investigations of Membrane-Bound CYP2C19 Polymorphisms Reveal Distinct Mechanisms for Peripheral Variants by Long-Range Effects on the Enzymatic Activity

Mol. BioSyst., 2017, Accepted Manuscript DOI: 10.1039/C6MB00827E, PaperYing-Lu Cui, Rong-Ling Wu Increasing sophistication in methods used to account for human polymorphisms in susceptibility to drug metabolism has been one of the success stories in the prevention of adverse drug reaction. Genetic... The content of this RSS Feed (c) The Royal Society of Chemistry

Source: RSC - Molecular Biosystems - February 9, 2017 Category: Molecular Biology Authors: Ying-Lu Cui Source Type: research