Antiviral immunity: CD4+ T cells open the door for antibodies
Nature Reviews Immunology 16, 404 (2016).
doi:10.1038/nri.2016.71
Author: Olive Leavy
Memory CD4+ T cells promote vascular permeability, allowing protective antiviral antibodies to access neuronal tissue. (Source: Nature Reviews Immunology)
Source: Nature Reviews Immunology - June 12, 2016 Category: Allergy & Immunology Authors: Olive Leavy Tags: Research Highlight Source Type: research
Origins of the cytolytic synapse
Nature Reviews Immunology 16, 421 (2016).
doi:10.1038/nri.2016.54
Authors: Maike de la Roche, Yukako Asano & Gillian M. Griffiths
Cytotoxic T lymphocytes (CTLs) kill virus-infected and tumour cells with remarkable specificity. Upon recognition, CTLs form a cytolytic immune synapse with their target cell, and marked reorganization of both the actin and the microtubule cytoskeletons brings the centrosome up to the plasma membrane to the (Source: Nature Reviews Immunology)
Source: Nature Reviews Immunology - June 5, 2016 Category: Allergy & Immunology Authors: Maike de la RocheYukako AsanoGillian M. Griffiths Tags: Review Source Type: research
Tumour immunology: A checkpoint for NK cells
Nature Reviews Immunology 16, 402 (2016).
doi:10.1038/nri.2016.68
Author: Yvonne Bordon
The SOCS family member CIS is a crucial negative regulator of IL-15-induced signalling in NK cells. (Source: Nature Reviews Immunology)
Source: Nature Reviews Immunology - June 5, 2016 Category: Allergy & Immunology Authors: Yvonne Bordon Tags: Research Highlight Source Type: research
Neutrophil migration in infection and wound repair: going forward in reverse
Nature Reviews Immunology 16, 378 (2016).
doi:10.1038/nri.2016.49
Authors: Sofia de Oliveira, Emily E. Rosowski & Anna Huttenlocher
Neutrophil migration and its role during inflammation has been the focus of increased interest in the past decade. Advances in live imaging and the use of new model systems have helped to uncover the behaviour of neutrophils in injured and infected tissues. Although neutrophils were (Source: Nature Reviews Immunology)
Source: Nature Reviews Immunology - May 26, 2016 Category: Allergy & Immunology Authors: Sofia de OliveiraEmily E. RosowskiAnna Huttenlocher Tags: Review Source Type: research
The influence of skin microorganisms on cutaneous immunity
Nature Reviews Immunology 16, 353 (2016).
doi:10.1038/nri.2016.48
Authors: Yasmine Belkaid & Samira Tamoutounour
The skin is a complex and dynamic ecosystem that is inhabited by many microorganisms. Recent evidence highlights the profound reliance of the skin immune system on its resident microbiota for both host defence and tissue repair. This tissue is also a primary target for infections, (Source: Nature Reviews Immunology)
Source: Nature Reviews Immunology - May 26, 2016 Category: Allergy & Immunology Authors: Yasmine BelkaidSamira Tamoutounour Tags: Review Source Type: research
