Origins of the cytolytic synapse

Nature Reviews Immunology 16, 421 (2016).
doi:10.1038/nri.2016.54

Authors: Maike de la Roche, Yukako Asano & Gillian M. Griffiths
Cytotoxic T lymphocytes (CTLs) kill virus-infected and tumour cells with remarkable specificity. Upon recognition, CTLs form a cytolytic immune synapse with their target cell, and marked reorganization of both the actin and the microtubule cytoskeletons brings the centrosome up to the plasma membrane to the

Source: Nature Reviews Immunology - June 5, 2016 Category: Allergy & Immunology Authors: Maike de la RocheYukako AsanoGillian M. Griffiths Tags: Review Source Type: research