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Synapse, Ahead of Print. (Source: Synapse)
Source: Synapse - February 19, 2018 Category: Neurology Source Type: research
Fatty acid binding protein deletion prevents stress ‐induced preference for cocaine and dampens stress‐induced corticosterone levels
This study examined the effects of genetic deletion of FABP 5/7 on cocaine preference, as assessed by the Conditioned Place Preference (CPP) paradigm. Male and female wild type (WT) and FABP 5/7 KO mice showed similar acquisition of cocaine CPP, with no differences found in overall locomotor activity. In addition, while male and female WT mice showed stress‐induced CPP for cocaine, male and female FABP 5/7 KO mice failed to show a stress‐induced preference for the cocaine‐paired chamber. Additionally, serum corticosterone levels were analyzed to explore any potential differences in stress response that may be respons...
Source: Synapse - February 19, 2018 Category: Neurology Authors: John Hamilton, Matthew Marion, Antonio Figueiredo, Brendan H. Clavin, Dale Deutsch, Martin Kaczocha, Samir Haj ‐Dahmane, Panayotis K. Thanos Tags: RESEARCH ARTICLE Source Type: research
Reference tissue models in the assessment of 11C ‐DTBZ binding to the VMAT2 in rat striatum: A test‐retest reproducibility study
Synapse, EarlyView. (Source: Synapse)
Source: Synapse - February 7, 2018 Category: Neurology Source Type: research
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Synapse, Ahead of Print. (Source: Synapse)
Source: Synapse - February 7, 2018 Category: Neurology Source Type: research
Intracerebroventricular Administration of Growth Hormone Induces Morphological Changes in Pyramidal Neurons of the Hippocampus and Prefrontal Cortex in Adult Rats
This article is protected by copyright. All rights reserved.
The intracerebroventricular administration of growth hormone (GH) increases the total dendritic length of pyramidal neurons in the prefrontal cortex and in the CA1 region of hippocampus. The effect of this hormone on structural plasticity could explain the mnemonic and restorative effects related with GH in rodents and humans. (Source: Synapse)
Source: Synapse - February 5, 2018 Category: Neurology Authors: Juan David Olivares Hern ández, Fabio García‐García, Israel Camacho‐Abrego, Gonzalo Flores, Enrique Juárez‐Aguilar Tags: Research Article Source Type: research
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Synapse, Ahead of Print. (Source: Synapse)
Source: Synapse - February 2, 2018 Category: Neurology Source Type: research
Reference Tissue Models in the Assessment of 11C ‐DTBZ Binding to the VMAT2 in Rat Striatum: A Test‐retest Reproducibility Study
Conclusions: To the best of our knowledge this is the first report on longitudinal studies for 11C‐DTBZ in rats using reference tissue methods. Excellent inter‐ and intra‐subject reproducibility was obtained with the multilinear reference MRTM2, suggesting this as the best method to compare longitudinal studies, whereas the SCR method had poor reliability. Logan method, on the other hand, is a method simple to compute that shows accurate reproducibility with a reasonable level of inter‐ and intra‐subject variability allowing crossover studies to follow‐up the uptake of 11C‐DTBZ in rat striatum. This article i...
Source: Synapse - January 30, 2018 Category: Neurology Authors: A. Avenda ño‐Estrada, M.A. Ávila‐Rodríguez Tags: Research Article Source Type: research
Issue Information
(Source: Synapse)
Source: Synapse - January 25, 2018 Category: Neurology Tags: ISSUE INFORMATION Source Type: research
Quantifying the Effect of Light Activated Outer and Inner Retinal Inhibitory Pathways on Glutamate Release from Mixed Bipolar Cells
This article is protected by copyright. All rights reserved.
Functional characterization of amacrine cell‐mediated, GABAergic inner retinal and horizontal cell‐mediated, non‐GABAergic outer retinal inhibitory processes was performed by quantifying their efficiency of inhibiting light‐evoked glutamate release from the axon terminals of Mb type bipolar cells at various stimulus intensities. (Source: Synapse)
Source: Synapse - January 23, 2018 Category: Neurology Authors: Mikhail Y Lipin, Jozsef Vigh Tags: Research Article Source Type: research
Quantifying the effect of light activated outer and inner retinal inhibitory pathways on glutamate release from mixed bipolar cells.
Synapse,Volume 72, Issue 5, May 2018. (Source: Synapse)
Source: Synapse - January 23, 2018 Category: Neurology Source Type: research
Activity ‐dependent plasticity of presynaptic GABAB receptors at parallel fiber synapses
Synapse,Volume 72, Issue 5, May 2018. (Source: Synapse)
Source: Synapse - January 23, 2018 Category: Neurology Source Type: research
Activity ‐dependent plasticity of presynaptic GABAB receptors at parallel fiber synapses
This article is protected by copyright. All rights reserved.
Using a combination of patch‐clamp electrophysiology and 2‐photon microscopy, the authors show that 4 Hz stimulation reduces presynaptic GABAB receptor‐mediated inhibition of neurotransmitter release. This work demonstrates plasticity of presynaptic receptor expression in physiological conditions. (Source: Synapse)
Source: Synapse - January 23, 2018 Category: Neurology Authors: Adeline Orts ‐Del'Immagine, Jason R. Pugh Tags: Research Article Source Type: research
Crocin improved amyloid beta induced long ‐term potentiation and memory deficits in the hippocampal CA1 neurons in freely moving rats
This article is protected by copyright. All rights reserved.
• Bilaterally beta‐amyloid (Aβ) administration into the frontal cortex increased memory deficit, which intra‐peritoneal injection of crocin significantly improved Aβ‐induced spatial memory impairment.
• Crocin treatment significantly attenuate c‐Fos level and neuronal apoptosis in hippocampus induced by Aβ administration into the frontal cortex.
• Crocin antagonize the blocking effect of Aβ‐induced LTP deficits in freely moving rat. (Source: Synapse)
Source: Synapse - January 22, 2018 Category: Neurology Authors: Mohammadmehdi Hadipour, Gholamreza Kaka, Farideh Bahrami, Gholam Hossein Meftahi, Gila Pirzad Jahromi, Alireza Mohammadi, Hedayat Sahraei Tags: Research Article Source Type: research
Crocin improved amyloid beta induced long ‐term potentiation and memory deficits in the hippocampal CA1 neurons in freely moving rats
Synapse,Volume 72, Issue 5, May 2018. (Source: Synapse)
Source: Synapse - January 22, 2018 Category: Neurology Source Type: research
