Activity ‐dependent plasticity of presynaptic GABAB receptors at parallel fiber synapses

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Using a combination of patch‐clamp electrophysiology and 2‐photon microscopy, the authors show that 4 Hz stimulation reduces presynaptic GABAB receptor‐mediated inhibition of neurotransmitter release. This work demonstrates plasticity of presynaptic receptor expression in physiological conditions.

Source: Synapse - January 23, 2018 Category: Neurology Authors: Adeline Orts ‐Del'Immagine, Jason R. Pugh Tags: Research Article Source Type: research