Supplementation with inhibits expression of inflammatory mediators in the gastric mucosa of -infected mice
Oxidative stress is involved in the pathogenesis of Helicobacter pylori (H. pylori)-associated gastric ulceration and carcinogenesis. The oxidant-sensitive transcription factor, nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) regulates expression of inflammatory mediators such as interferon-gamma (IFN-γ), cyclooxygenase-2 (COX-2), and inducible nitric oxide synthase (iNOS). These inflammatory mediators increased in gastric mucosal tissues from patients infected with H. pylori. (Source: Nutrition Research)
Source: Nutrition Research - January 5, 2016 Category: Nutrition Authors: Aryoung Kim, Joo Weon Lim, Hoguen fme, Hyeyoung Kim Source Type: research
Docosahexaenoic acid at the sn-2 position of structured triacylglycerols improved n-3 polyunsaturated fatty acid assimilation in tissues of hamsters
In this study, we hypothesized that the incorporation of docosahexaenoic acid (DHA) in tissues will be higher when it is ingested as triacylglycerols (TAG) structured at the sn-2 position, which enhances efficacy and health benefits of dietary DHA n-3 supplementation. Ten-week-old Golden Syrian male hamsters were randomly allocated into 4 dietary groups with 10 animals in each: linseed oil (LSO; control group), fish oil (FO), fish oil ethyl esters (FO-EE), and structured DHA at the sn-2 position of TAG (DHA-SL). (Source: Nutrition Research)
Source: Nutrition Research - January 4, 2016 Category: Nutrition Authors: Narcisa M. Bandarra, Paula A. Lopes, Susana V. Martins, Júlia Ferreira, Cristina M. Alfaia, Eva A. Rolo, Jorge J. Correia, Rui M.A. Pinto, Rebeca P. Ramos-Bueno, Irineu Batista, José A.M. Prates, José L. Guil-Guerrero Tags: Original Research Source Type: research
Choline Supplementation Alters Some Amino Acid Concentrations with No Change in Homocysteine in Children with Cystic Fibrosis and Pancreatic Insufficiency
The present study determined the plasma amino acid status in children with cystic fibrosis (CF) and pancreatic insufficiency (PI) in the modern medical and nutritional care setting and investigated the effect of choline supplementation on amino acid status. A total of 110 children, ages 5 to 18 years, with CF and PI were randomized to receive choline-enriched structured lipid (LYM-X-SORB™, LXS) or placebo with similar calorie and fat content. Plasma amino acids were measured at baseline, 3, and 12 months. (Source: Nutrition Research)
Source: Nutrition Research - December 28, 2015 Category: Nutrition Authors: Belal Alshaikh, Joan I. Schall, Asim Maqbool, Maria Mascarenhas, Michael J. Bennett, Virginia A. Stallings Tags: Original Research Source Type: research
Dietary Patterns in Men and Women are Simultaneously Determinants of Altered Glucose Metabolism and Bone Metabolism
We hypothesized that diet would have direct effects on glucose metabolism with direct and indirect effects on bone metabolism in a cohort of Canadian adults. We assessed dietary patterns [Prudent (fruit, vegetables, whole grains, fish, and legumes) and Western (soft drinks, potato chips, French fries, meats, and desserts)] from a semi-quantitative food frequency questionnaire. We used fasting blood samples to measure glucose, insulin, homeostatic model assessment insulin resistance (HOMA-IR), 25-hydroxyvitamin D (25OHD), parathyroid hormone (PTH), bone-specific alkaline phosphatase (BAP, a bone formation marker), and serum...
Source: Nutrition Research - December 23, 2015 Category: Nutrition Authors: Lisa Langsetmo, Susan I. Barr, Kaberi Dasgupta, Claudie Berger, Christopher S. Kovacs, Robert G. Josse, Jonathan D. Adachi, David A. Hanley, Jerilynn C. Prior, Jacques P. Brown, Suzanne N. Morin, Kenneth S. Davison, David Goltzman, Nancy Kreiger Source Type: research
Family income per capita, age and smoking status are predictors of low fiber intake in residents of São Paulo - Brazil
We hypothesized that dietary total fiber intake may be below recommendations, and the intake of total, soluble and insoluble fiber may be associated with demographic, lifestyle and socioeconomic factors. Data were drawn from the Health Survey of São Paulo, a cross-sectional population-based study. Adolescents, adults and elderly persons living in São Paulo city were included. Demographic, lifestyle and anthropometric data were collected from households. Dietary intake was measured using two 24-hour dietary recalls. (Source: Nutrition Research)
Source: Nutrition Research - December 23, 2015 Category: Nutrition Authors: Paula Victória Félix dos Santos, Cristiane Hermes Sales, Diva Aliete Santos Vieira, Mariane de Mello Fontanelli, Dirce Maria Marchioni, Regina Mara Fisberg Source Type: research
Relationship of nutrition knowledge and self-reported dietary behaviors with urinary excretion of sodium and potassium: comparison between dietitians and non-dietitians
The effectiveness of better nutrition knowledge and dietary behavior on healthier dietary intake is still controversial. We hypothesized that nutritional knowledge and dietary behavior are associated with sodium and potassium intake in adult women. A cross-sectional study was conducted at welfare facilities located in 20 areas of Japan. 99 female dietitians and 117 non-dietitians aged 20 to 69years participated. Sodium and potassium intake were assessed with two 24-h urine collections and four-day semi-weighed diet records. (Source: Nutrition Research)
Source: Nutrition Research - December 23, 2015 Category: Nutrition Authors: Minami Sugimoto, Keiko Asakura, Shizuko Masayasu, Satoshi Sasaki Source Type: research
Family income per capita, age, and smoking status are predictors of low fiber intake in residents of São Paulo, Brazil
We hypothesized that dietary total fiber intake may be less than recommendations and that the intake of total, soluble, and insoluble fiber may be associated with demographic, lifestyle, and socioeconomic factors. Data were drawn from the Health Survey of São Paulo, a cross-sectional population-based study. Adolescents, adults, and elderly persons living in São Paulo city were included. Demographic, lifestyle, and anthropometric data were collected from households. Dietary intake was measured using two 24-hour dietary recalls. (Source: Nutrition Research)
Source: Nutrition Research - December 22, 2015 Category: Nutrition Authors: Paula Victória Félix dos Santos, Cristiane Hermes Sales, Diva Aliete Santos Vieira, Mariane de Mello Fontanelli, Dirce Maria Marchioni, Regina Mara Fisberg Tags: Original Research Source Type: research
Suppressive effects of polyozellin on TGFBIp-mediated septic responses in human endothelial cells and mice
Polyozellus multiplex (Thelephoraceae) is a wild mushroom in Korea and Japan and is usually harvested in early autumn for food. Polyozellin, a major constituent of the edible mushroom Polyozellus multiplex, has been known to exhibit biological activities such as anti-oxidative and anti-inflammatory effects. Transforming growth factor β-induced protein (TGFBIp) is an extracellular matrix protein whose expression in several cell types is greatly increased by TGF-β. TGFBIp is released by human umbilical vein endothelial cells (HUVECs) and functions as a mediator of experimental sepsis. (Source: Nutrition Research)
Source: Nutrition Research - December 17, 2015 Category: Nutrition Authors: Byeongjin Jung, Eun-Ju Yang, Jong-Sup Bae Tags: Original Research Source Type: research
seed attenuates hepatic steatosis and promotes M2 macrophage polarization in high-fat diet–fed mice
In this study, we hypothesized that DWJ504, an extract of O ficus-indica seed, would ameliorate hepatic steatosis and inflammation by regulating hepatic de novo lipogenesis and macrophage polarization against experimental nonalcoholic steatohepatitis. Mice were fed a normal diet or a high-fat diet (HFD) for 10 weeks. (Source: Nutrition Research)
Source: Nutrition Research - December 12, 2015 Category: Nutrition Authors: Jung-Woo Kang, Jun-Kyu Shin, Eun-Ji Koh, Hyojeong Ryu, Hyoung Ja Kim, Sun-Mee Lee Tags: Original Research Source Type: research
seed attenuates hepatic steatosis and promotes M2 macrophage polarization in high-fat diet-fed mice
In this study, we hypothesized that DWJ504, an extract of Opuntia ficus indica seed, would ameliorate hepatic steatosis and inflammation by regulating hepatic de novo lipogenesis and macrophage polarization against experimental non-alcoholic steatohepatitis. Mice were fed a normal diet (ND) or a high-fat diet (HFD) for 10 weeks. (Source: Nutrition Research)
Source: Nutrition Research - December 12, 2015 Category: Nutrition Authors: Jung-Woo Kang, Jun-Kyu Shin, Eun-Ji Koh, Hyojeong Ryu, Hyoung Ja Kim, Sun-Mee Lee Tags: Original Research Source Type: research
A high-fat diet increases body weight and circulating estradiol concentrations but does not improve bone structural properties in ovariectomized mice
The objective of the study was to determine whether high-fat diet induced obesity affects bone structure and alters markers of bone turnover in ovariectomized (OVX) mice. We hypothesized that a high-fat diet would increase body weight gain and serum estradiol levels in OVX mice but would not improve bone structural parameter in OVX mice. Thirty-five C57BL/6 mice were either sham-operated or OVX at age of 4 mo and then fed either a normal-fat diet (10% kcal as fat) or a high-fat diet (45% kcal as fat with extra fat from lard) ad libitum for 11 wks. (Source: Nutrition Research)
Source: Nutrition Research - December 12, 2015 Category: Nutrition Authors: Jay J. Cao, Brian R. Gregoire Tags: Original Research Source Type: research
Cinnamon users with prediabetes have a better fasting working memory: a cross-sectional function study
Working memory (WM) is impaired in prediabetes. We hypothesized that culinary herbs and spices may decrease insulin resistance (IR) and improve WM in prediabetes. Healthy people aged ≥60 years with prediabetes (fasting blood glucose 100-125 mg/dL) (47 men and 46 women) whose food and culinary herb intakes were established with a food frequency questionnaire had body composition assessed and fasting glucose and insulin measured. Working memory and Mini-Mental State Examination (MMSE) were assessed on the same occasion. (Source: Nutrition Research)
Source: Nutrition Research - December 8, 2015 Category: Nutrition Authors: Mark L. Wahlqvist, Meei-Shyuan Lee, Jiunn-Tay Lee, Chih-Cheng Hsu, Yu-Ching Chou, Wen-Hui Fang, Hsiao-Yu Liu, Lili Xiu, Zane B. Andrews Tags: Communication Source Type: research
Cinnamon users with pre-diabetes have a better fasting working memory: a cross–sectional function study
Working memory (WM) is impaired in pre-diabetes. We hypothesized that culinary herbs and spices may decrease insulin resistance (IR) and improve WM in pre-diabetes. Healthy people aged ≥60 years with pre-diabetes (fasting blood glucose 100-125 mg/dL) (47 men and 46 women), whose food and culinary herb intakes were established with a food frequency questionnaire had body composition assessed and fasting glucose and insulin measured. WM and Mini Mental State Examination (MMSE) were assessed on the same occasion. (Source: Nutrition Research)
Source: Nutrition Research - December 8, 2015 Category: Nutrition Authors: Mark L. Wahlqvist, Meei-Shyuan Lee, Jiunn-Tay Lee, Chih-Cheng Hsu, Yu-Ching Chou, Wen-Hui Fang, Hsiao-Yu Liu, Lili Xiu, Zane B. Andrews Tags: Communication Source Type: research
Circulating Adiponectin Concentrations are Increased by Dietary Resistant Starch and Correlate with Serum 25-Hydroxycholecalciferol Concentrations and Kidney Function in Zucker Diabetic Fatty Rats
We previously reported that dietary resistant starch type 2 (RS) prevented proteinuria and promoted vitamin D balance in type 2 diabetic (T2D) rats. Here, our primary objective was to identify potential mechanisms that could explain our earlier observations. We hypothesized that RS could promote adiponectin secretion and regulate the renin-angiotensin system activity in the kidney. Lean Zucker rats (n=5) were fed control diet (LC); Zucker diabetic fatty (ZDF) rats (n = 5/group) were fed either an AIN-93G control diet (DC), or AIN-93G diet containing either 10% RS (MRS) or 20% RS (HRS) for 6 wks. (Source: Nutrition Research)
Source: Nutrition Research - December 8, 2015 Category: Nutrition Authors: Gar Yee Koh, Rachel Derscheid, Kelly N.Z. Fuller, Rudy J. Valentine, Shu En Leow, Leah Reed, Emily Wisecup, Kevin L. Schalinske, Matthew J. Rowling Source Type: research
Long-term ketogenic diet contributes to glycemic control but promotes lipid accumulation and hepatic steatosis in type 2 diabetic mice
In this study, we hypothesized that the KD would ameliorate the progression of diabetes, but lead to disruptions in lipid metabolism and hepatic steatosis in a mouse model of diabetes. A type 2 diabetic mouse model fed a high-fat diet (HFD) and administered streptozotocin treatment before given the test diets for eight weeks. Subsequently, ameliorated glucose and insulin tolerance in KD-fed diabetic mice was found, although the body weight of HFD and KD-fed mice was similar. (Source: Nutrition Research)
Source: Nutrition Research - December 7, 2015 Category: Nutrition Authors: Xiaoyu Zhang, Juliang Qin, Yihan Zhao, Jueping Shi, Rong Lan, Yunqiu Gan, Hua Ren, Bing Zhu, Min Qian, Bing Du Source Type: research
