Seasoning ingredient variety, but not quality, is associated with greater intake of beans and rice among urban Costa Rican adults
Exposure to a variety of flavors may promote food enjoyment, but few studies have examined the relationship between food seasoning and food intake. We hypothesized that using a higher variety (number) of eleven seasonings to prepare two staple foods (beans, white rice) would be associated with intake of those foods in a population-based case–control study of Costa Rican adults in urban vs. rural areas (n=1,025), where cooking and dietary practices differ. Participants were surveyed about the variety of seasoning ingredients added when preparing beans or rice. (Source: Nutrition Research)
Source: Nutrition Research - April 6, 2016 Category: Nutrition Authors: Maya K. Vadiveloo, Hannia Campos, Josiemer Mattei Source Type: research

Genistein supplementation prevents weight gain but promotes oxidative stress and inflammation in the vasculature of female obese ob/ob mice
Obesity, a state of chronic low-grade inflammation, is strongly associated with the development of hypertension and diabetes. Superoxide, a free radical elevated in obese individuals, promotes hypertension through scavenging the endogenous vasodilator nitric oxide. The hypothesis was a genistein-enriched diet would promote weight loss and reduce oxidative stress and inflammation in the vasculature of intact female ob/ob mice. Aortas and mesenteric arteries were isolated from female ob/ob mice fed genistein-free (0mg genistein/kg diet; n=6), standard chow (200 –300mg genistein/kg diet; n=11) or genistein-enriched (600mg g...
Source: Nutrition Research - March 31, 2016 Category: Nutrition Authors: Anna Simperova, Layla Al-Nakkash, James J. Faust, Karen L. Sweazea Source Type: research

A combination of omega-3 fatty acids, folic acid and B-group vitamins is superior at lowering homocysteine than omega-3 alone: a meta-analysis
The aim of the study was to assess whether omega-3 polyunsaturated fatty acid supplementation alone or in combination with folic acid and B-group vitamins is effective in lowering homocysteine. The Medline Ovid, Embase and Cochrane databases were searched for randomized-controlled trial studies that intervened with omega-3 supplementation (with or without folic acid) and measured changes in homocysteine concentration. Studies were pooled using a random effects model for meta-analysis. Three different models were analyzed: all trials combined, omega-3 polyunsaturated fatty acid trials, and omega-3 polyunsaturated fatty acid...
Source: Nutrition Research - March 31, 2016 Category: Nutrition Authors: Samantha Loren Dawson, Steven John Bowe, Timothy Charles Crowe Source Type: research

Genistein supplementation prevents weight gain but promotes oxidative stress and inflammation in the vasculature of female obese ob/ob mice
Obesity, a state of chronic low-grade inflammation, is strongly associated with the development of hypertension and diabetes. Superoxide, a free radical elevated in obese individuals, promotes hypertension through scavenging the endogenous vasodilator nitric oxide. The hypothesis was a genistein-enriched diet would promote weight loss and reduce oxidative stress and inflammation in the vasculature of intact female ob/ob mice. Aortas and mesenteric arteries were isolated from female ob/ob mice fed genistein-free (0 mg genistein/kg diet; n=6), standard chow (200-300 mg genistein/kg diet; n=11) or genistein-enriched (600 mg g...
Source: Nutrition Research - March 31, 2016 Category: Nutrition Authors: Anna Simperova, Layla Al-Nakkash, James J. Faust, Karen L. Sweazea Source Type: research

Association between Plasma Endocannabinoids and Appetite in Hemodialysis Patients: a Pilot Study
Uremia-associated anorexia may be related to altered levels of long chain n-6 and n-3 polyunsaturated fatty acid (PUFA) derived circulating endocannabinoids (EC) and EC-like compounds that are known to mediate appetite. Our study’s hypothesis was that such molecules are associated with appetite in patients with end-stage renal disease. A cross-sectional observational study was performed in 20 chronic hemodialysis patients (9 females, 11 males) and 10 healthy female controls in whom appetite was assessed using the Simplified Nutritional Appetite Questionnaire (SNAQ) and blood drawn in the fasting (and when applicable) pre...
Source: Nutrition Research - March 30, 2016 Category: Nutrition Authors: Allon N. Friedman, Jeffrey Kim, Shaun Kaiser, Theresa L. Pedersen, John W. Newman, Bruce A. Watkins Source Type: research

Maternal protein restriction during gestation impairs female offspring pancreas development in the rat
A maternal low-protein (LP) diet programs fetal pancreatic islet β-cell development and function and predisposes offspring to metabolic dysfunction later in life. We hypothesized that maternal protein restriction during pregnancy differentially alters β- and α-cell populations in offspring by modifying islet ontogeny and function throughout life. We aimed to i nvestigate the effect of an LP maternal diet on pancreatic islet morphology and cellular composition in female offspring on postnatal days (PNDs) 7, 14, 21, 36, and 110. (Source: Nutrition Research)
Source: Nutrition Research - March 29, 2016 Category: Nutrition Authors: Lizbeth Calzada, Ang élica Morales, Tonantzin C. Sosa-Larios, Luis A. Reyes-Castro, Guadalupe L. Rodríguez-González, Verónica Rodríguez-Mata, Elena Zambrano, Sumiko Morimoto Source Type: research

Plasma equol concentration is not associated with breast cancer and fibrocystic breast conditions among women in Shanghai, China
Equol (a bacterial metabolite of the soy isoflavone daidzein) is produced by 30% to 50% of humans and may be associated with health outcomes. We hypothesized that plasma equol would be inversely associated with risks of fibrocystic breast conditions (FBC) and breast cancer (BC). Plasma from women in a breast self-examination trial in Shanghai with BC (n=269) or FBC (n=443), and age-matched controls (n=1027) was analyzed for isoflavones. Equol was grouped into categories ( < 20, 20- < 45, and ≥45nmol/L) and, among women with daidzein ≥20nmol/L, the log10 equol:daidzein ratio was grouped into tertiles. (Source: Nutrition Research)
Source: Nutrition Research - March 29, 2016 Category: Nutrition Authors: Charlotte Atkinson, Roberta M. Ray, Wenjin Li, Ming-Gang Lin, Dao Li Gao, Jackilen Shannon, Helge Stalsberg, Peggy L. Porter, Cara L. Frankenfeld, Kristiina W ähälä, David B. Thomas, Johanna W. Lampe Source Type: research

Maternal protein restriction during gestation impairs female offspring pancreas development in the rat
A maternal low-protein (LP) diet programs fetal pancreatic islet beta cell development and function and predisposes offspring to metabolic dysfunction later in life. We hypothesized that maternal protein restriction during pregnancy differentially alters beta and alpha cell populations in offspring by modifying islet ontogeny and function throughout life. We aimed to investigate the effect of an LP maternal diet on pancreatic islet morphology and cellular composition in female offspring on postnatal day (PND) 7, 14, 21, 36 and 110. (Source: Nutrition Research)
Source: Nutrition Research - March 29, 2016 Category: Nutrition Authors: Lizbeth Calzada, Angélica Morales, Tonantzin C. Sosa-Larios, Luis A. Reyes-Castro, Guadalupe L. Rodríguez-González, Verónica Rodríguez-Mata, Elena Zambrano, Sumiko Morimoto Source Type: research

Plasma equol concentration is not associated with breast cancer and fibrocystic breast conditions among women in Shanghai, China
Equol (a bacterial metabolite of the soy isoflavone daidzein) is produced by 30-50% of humans and may be associated with health outcomes. We hypothesized that plasma equol would be inversely associated with risks of fibrocystic breast conditions (FBC) and breast cancer (BC). Plasma from women in a breast self-examination trial in Shanghai with BC (n=269) or FBC (n=443), and age-matched controls (n=1027) was analyzed for isoflavones. Equol was grouped into categories ( (Source: Nutrition Research)
Source: Nutrition Research - March 29, 2016 Category: Nutrition Authors: Charlotte Atkinson, Roberta M. Ray, Wenjin Li, Ming-Gang Lin, Dao Li Gao, Jackilen Shannon, Helge Stalsberg, Peggy L. Porter, Cara L. Frankenfeld, Kristiina Wähälä, David B. Thomas, Johanna W. Lampe Source Type: research

Low-molecular-weight fractions of Alcalase hydrolyzed egg ovomucin extract exert anti-inflammatory activity in human dermal fibroblasts through the inhibition of tumor necrosis factor–mediated nuclear factor κB pathway
Ovomucin is a mucin-like protein from egg white with a variety of biological functions. We hypothesized that ovomucin-derived peptides might exert anti-inflammatory activity. The specific objectives were to test the anti-inflammatory activities of different ovomucin hydrolysates and its various fractions in human dermal fibroblasts, and to understand the possible molecular mechanisms. Three ovomucin hydrolysates were prepared and desalted; only the desalted Alcalase hydrolysate showed anti-inflammatory activity. (Source: Nutrition Research)
Source: Nutrition Research - March 28, 2016 Category: Nutrition Authors: Xiaohong Sun, Subhadeep Chakrabarti, Jun Fang, Yulong Yin, Jianping Wu Source Type: research

Low Molecular-Weight Fractions of Alcalase Hydrolyzed Egg Ovomucin Extract Exert Anti-Inflammatory Activity in Human Dermal Fibroblasts through the Inhibition of TNF Mediated NF-κB Pathway
Ovomucin is a mucin-like protein from egg white with a variety of biological functions. We hypothesized that ovomucin derived peptides might exert anti-inflammatory activity. The specific objectives were to test the anti-inflammatory activities of different ovomucin hydrolysates and its various fractions in human dermal fibroblasts, and to understand the possible molecular mechanisms. Three ovomucin hydrolysates were prepared and desalted; only the desalted Alcalase hydrolysate showed anti-inflammatory activity. (Source: Nutrition Research)
Source: Nutrition Research - March 28, 2016 Category: Nutrition Authors: Xiaohong Sun, Subhadeep Chakrabarti, Jun Fang, Yulong Yin, Jianping Wu Source Type: research

Consumption of canned citrus fruit meals increases human plasma beta-cryptoxanthin concentration whereas lycopene and beta-carotene concentrations did not change in healthy adults
Several studies suggest that beta-cryptoxanthin has a greater plasma response from its common food sources than other carotenoids such as beta-carotene and lycopene. The hypothesis of this study is that changes in plasma beta-cryptoxanthin concentrations will be greater than changes in plasma beta-carotene or lycopene concentrations even if these carotenoids are fed in a similar food matrix, such as citrus fruit. We tested this hypothesis by measuring changes in plasma concentrations of beta-cryptoxanthin, lycopene, and beta-carotene after feeding measured amounts of canned tangerines and pink grapefruit to healthy non-smo...
Source: Nutrition Research - March 19, 2016 Category: Nutrition Authors: Chenghao H. Zhu, Erik R. Gertz, Yimeng Cai, Betty J. Burri Tags: Original Research Source Type: research

Consumption of canned citrus fruit meals increases human plasma β-cryptoxanthin concentration, whereas lycopene and β-carotene concentrations did not change in healthy adults
Several studies suggest that β-cryptoxanthin has a greater plasma response from its common food sources than other carotenoids such as β-carotene and lycopene. The hypothesis of this study is that changes in plasma β-cryptoxanthin concentrations will be greater than changes in plasma β-carotene or lycopene concentrations even if these carotenoids are fed in a similar food matrix, such as citrus fruit. We tested this hypothesis by measuring changes in plasma concentrations of β-cryptoxanthin, lycopene, and β-carotene after feeding measured amounts of canned tangerines and pink grapefruit to healthy nonsmoking adult hu...
Source: Nutrition Research - March 18, 2016 Category: Nutrition Authors: Chenghao H. Zhu, Erik R. Gertz, Yimeng Cai, Betty J. Burri Tags: Original Research Source Type: research

Maternal vitamin C deficiency does not reduce hippocampal volume and β-tubulin III intensity in prenatal guinea pigs
Marginal vitamin C (vitC) deficiency affects 5-10% of adults including subpopulations such as pregnant women and newborns. Animal studies link vitC deficiency to deleterious effects on the developing brain, but exactly how the brain adapts to vitC deficiency and the mechanisms behind the observed deficits remain largely unknown. We hypothesized that vitC deficiency in utero may lead to a decreased neuronal maturation and increased cellular death giving rise to alterations of the hippocampal morphology in a guinea pig model. (Source: Nutrition Research)
Source: Nutrition Research - March 6, 2016 Category: Nutrition Authors: Stine N. Hansen, Janne G. Schjoldager, Maya D. Paidi, Jens Lykkesfeldt, Pernille Tveden-Nyborg Tags: Communication Source Type: research

Aster spathulifolius Maxim extract reduces body weight and fat mass in obese humans
Aster spathulifolius Maxim (AS), a perennial herb of the genus Aster within the family Asteraceae, induced weight loss in a rat model of diet-induced obesity. We hypothesized that AS could also reduce body weight in obese humans. Therefore, we performed a randomized, double-blind, placebo-controlled clinical trial in Korea to evaluate the effect of AS extract (ASE) on body weight and fat mass and its safety in obese humans. Forty-three obese subjects (body mass index [BMI] 25–30 kg/m2) aged ≥20 years were randomly assigned to the placebo or ASE group (700 mg/day of ASE), and were instructed to take a once-daily pill fo...
Source: Nutrition Research - March 3, 2016 Category: Nutrition Authors: In-Jin Cho, Se Young Choung, You-Cheol Hwang, Kyu Jeung Ahn, Ho Yeon Chung, In-Kyung Jeong Tags: Original Research Source Type: research