Twice weekly intake of farmed Atlantic salmon (Salmo salar) positively influences lipoprotein concentration and particle size in overweight men and women
The U.S. Dietary Guidelines for Americans recommend twice weekly fish intake. Farmed Atlantic salmon is a good source of omega-3 (n-3) fatty acids which have positive lipid modifying effects; however, it is unknown whether these responses are dose-dependent. Our primary research objective was to determine the effect of dose- dependent intake of farmed Atlantic salmon on lipoprotein particle (P) size and concentration. We hypothesized that LDL-P and HDL-P size and concentration would increase with salmon intake in a dose- dependent manner. (Source: Nutrition Research)
Source: Nutrition Research - June 26, 2016 Category: Nutrition Authors: Susan K. Raatz, LuAnn K. Johnson, Thad A. Rosenberger, Matthew J. Picklo Tags: Original Research Source Type: research

Sesamin ameliorates hepatic steatosis and inflammation in rats on a high-fat diet via LXRα and PPARα
In this study, we hypothesized that sesamin improves lipid homeostasis of Sprague Dawley (SD) rats fed a high-fat diet (HFD) by regulating the expression of genes related to de novo lipogenesis and β-oxidation. We induced NAFLD in rats with HFD and examined the effect of sesamin in vivo. (Source: Nutrition Research)
Source: Nutrition Research - June 26, 2016 Category: Nutrition Authors: Ruijuan Zhang, Yan Yu, Senke Hu, Jinghua Zhang, Haixia Yang, Bei Han, Yue Cheng, Xiaoqin Luo Tags: Original Research Source Type: research

Apple ethanol extract promotes proliferation of human adult stem cells, which involves the regenerative potential of stem cells
Tissue regeneration using adult stem cells (ASCs) has significant potential as a novel treatment for many degenerative diseases. Previous studies have established that age negatively affects the proliferation status and differentiation potential of ASCs, suggesting a possible limitation in their potential therapeutic use. Therefore, we hypothesized that apple extract might exert beneficial effects on ASCs. The specific objectives were to investigate the proliferative effect of apple ethanol extract on human adipose tissue-derived mesenchymal stem cells (ADSCs) and human cord blood-derived mesenchymal stem cells (CB-MSCs), ...
Source: Nutrition Research - June 25, 2016 Category: Nutrition Authors: Jienny Lee, Moon Sam Shin, Mi Ok Kim, Sunghee Jang, Sae Woong Oh, Mingyeong Kang, Kwangseon Jung, Yong Seek Park, Jongsung Lee Source Type: research

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials
Gastrointestinal microbiota, consisting of microbial communities in the gastrointestinal tract, play an important role in digestive, metabolic, and immune functioning. Preclinical studies on rodents have linked behavioral and neurochemical changes in the central nervous system with deficits or alterations in these bacterial communities. Moreover, probiotic supplementation in rodents has been shown to markedly change behavior, with correlated changes in central neurochemistry. While such studies have documented behavioral and mood-related supplementation effects, the significance of these effects in humans, especially in re...
Source: Nutrition Research - June 20, 2016 Category: Nutrition Authors: Meysam Pirbaglou, Joel Katz, Russell J. de Souza, Jennifer C. Stearns, Mehras Motamed, Paul Ritvo Tags: Review Source Type: research

Retraction notice to “Influence of vitamins and trace-elements on the incidence of respiratory infection in the elderly” (Nutr Res 2002;22:85–87)
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). (Source: Nutrition Research)
Source: Nutrition Research - June 13, 2016 Category: Nutrition Authors: Amrit L. Jain Tags: Retraction Notice Source Type: research

Retraction notice to “Influence of multinutrient supplement on immune responses and infection-related illness in 50-65 year old individuals” (Nutr Res 2002;22:5-11)
This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). (Source: Nutrition Research)
Source: Nutrition Research - June 13, 2016 Category: Nutrition Authors: R.K. Chandra Tags: Retraction Notice Source Type: research

Plum polyphenols inhibit colorectal aberrant crypt foci formation in rats: Potential role of the miR-143/AKT/mTOR axis
The objective of this study was to determine the underlying mechanisms that contribute to the anti-inflammatory and anti-tumorigenic properties of plum (Prunus salicina L.) polyphenols, including chlorogenic acid and neochlorogenic acid, in AOM-treated rats. The hypothesis was that plum polyphenolics suppress azoxymethane (AOM)-induced aberrant crypt foci formation through alterations in the AKT/mTOR pathway and relative micro-RNA expressions. (Source: Nutrition Research)
Source: Nutrition Research - June 12, 2016 Category: Nutrition Authors: Nivedita Banerjee, Hyemee Kim, Stephen T. Talcott, Nancy D. Turner, David H. Byrne, Susanne U. Mertens-Talcott Source Type: research

Cynanchum wilfordii Radix attenuates liver fat accumulation and damage by suppressing hepatic cyclooxygenase-2 and mitogen-activated protein kinase in mice fed with a high-fat and high-fructose diet
Excessive consumption of fat and fructose augments the pathological progression of nonalcoholic fatty liver disease through hepatic fibrosis, inflammation, and hepatic de novo lipogenesis. We hypothesized that supplementation with Cynanchum wilfordii extract (CWE) decreases fat accumulation in the liver by suppressing cyclooxygenase-2 (COX-2), the nuclear translocation of nuclear factor κB (NF-κB), and p38 mitogen-activated protein kinase (MAPK). The beneficial effect of CWE was evaluated in a murine model of nonalcoholic fatty liver disease. (Source: Nutrition Research)
Source: Nutrition Research - June 11, 2016 Category: Nutrition Authors: Seon-A Jang, SungRyul Lee, Eun-Hwa Sohn, Jaehyuk Yang, Dae Won Park, Yong Joon Jeong, Inhye Kim, Jung Eun Kwon, Hae Seong Song, Young Mi Cho, Xue Meng, Hyun Jung Koo, Se Chan Kang Source Type: research

Cynanchum wilfordii radix attenuates liver fat accumulation and damage by suppressing hepatic COX-2 and MAPK in mice fed with a high-fat and high-fructose diet
Excessive consumption of fat and fructose augments the pathological progression of nonalcoholic fatty liver disease (NAFLD) through hepatic fibrosis, inflammation, and hepatic de novo lipogenesis. We hypothesized that supplementation with Cynanchum wilfordii extract (CWE) decreases fat accumulation in the liver by suppressing cyclooxygenase-2 (COX-2), the nuclear translocation of nuclear factor κB (NF-κB), and p38 mitogen-activated protein kinase (MAPK). The beneficial effect of CWE was evaluated in a murine model of NAFLD. (Source: Nutrition Research)
Source: Nutrition Research - June 11, 2016 Category: Nutrition Authors: Seon-A Jang, SungRyul Lee, Eun-Hwa Sohn, Jaehyuk Yang, Dae Won Park, Yong Joon Jeong, Inhye Kim, Jung Eun Kwon, Hae Seong Song, Young Mi Cho, Xue Meng, Hyun Jung Koo, Se Chan Kang Source Type: research

Dietary butyrylated high-amylose starch reduces azoxymethane-induced colonic O6-methylguanine adducts in rats as measured by immunohistochemistry and high-pressure liquid chromatography
In this study, we hypothesized that a dietary intervention that specifically delivers butyrate to the large bowel (notably butyrylated high-amylose maize starch [HAMSB]) would reduce colonic levels of O6MeG in rats shortly after exposure to the deoxyribonucleic acid (DNA) alkylating agent azoxymethane (AOM) when compared with a low-amylose maize starch (LAMS). (Source: Nutrition Research)
Source: Nutrition Research - June 6, 2016 Category: Nutrition Authors: Richard K. Le Leu, Benjamin L. Scherer, Mark T. Mano, Jean M. Winter, Tamsin Lannagan, Richard J. Head, Trevor Lockett, Julie M. Clarke Tags: Original Research Source Type: research