β-Hydroxy-β-methylbutyrate attenuates cytokine response during sustained military training
This study tested the hypothesis that of 23 days of β-hydroxy-β-methylbutyrate (HMB) supplementation can maintain muscle mass and attenuate the immune and inflammatory response in combat soldiers during highly intense military training. Soldiers were randomly assigned to either a HMB (n = 6) or placebo (PL; n = 7) group and provided with 3 g · day−1 of either HMB or PL. During the final week of supplementation soldiers participated in extreme physical training, which included night navigation of 6–8 hours across difficult terrain carrying heavy loads combined with sleep deprivation (3.8 ± 3.0 h per night). (Source: Nutrition Research)
Source: Nutrition Research - February 20, 2016 Category: Nutrition Authors: Jay R. Hoffman, Yiftach Gepner, Jeffrey R. Stout, Mattan W. Hoffman, Daniel Ben-Dov, Shany Funk, Ido Daimont, Adam R. Jajtner, Jeremy R. Townsend, David D. Church, Ilan Shelef, Philip Rosen, Guy Avital, Yacov Chen, Hagai Frankel, Ishay Ostfeld Tags: Original Research Source Type: research
Time-restricted feeding reduces adiposity in mice fed a high-fat diet
This study tested the hypothesis that time-restricted feeding (TRF) reduces high-fat diet-induced increase in adiposity. Male C57BL/6 mice were fed the AIN93G or the high-fat diet ad libitum (ad lib); TRF of the high-fat diet for 12 or 8 hours during the dark cycle was initiated when high-fat diet-fed mice exhibited significant increases in body weight. Energy intake of TRF 12-hour group was not different from, while that of TRF 8-hour group was slightly but significantly lower than, that of the high-fat ad lib group. (Source: Nutrition Research)
Source: Nutrition Research - February 20, 2016 Category: Nutrition Authors: Sneha Sundaram, Lin Yan Source Type: research
Plasma riboflavin is a useful marker for studying riboflavin requirement in Chinese male adults
This study examines the changes of fasting plasma riboflavin and urinary riboflavin excretion in response to different riboflavin intake levels in Chinese male adults. (Source: Nutrition Research)
Source: Nutrition Research - February 18, 2016 Category: Nutrition Authors: Changjiang Guo, Jingyu Wei, Weina Gao, Lingling Pu, Zhenchuang Tang, Lingyan Li Tags: Original Research Source Type: research
Oat β-glucan depresses SGLT1 and GLUT2 mediated glucose transport in intestinal epithelial cells (IEC-6)
Oat β-glucan consumption is linked to reduced risk factors associated with diabetes and obesity by lowering glycemic response and serum level of low-density lipoproteins. The purpose of this study was to identify the mechanism of action of oat β-glucan at the interface between the gut wall and the lumen responsible for attenuating glucose levels. We proposed that viscous oat β-glucan acts as a physical barrier to glucose uptake in normally absorptive gut epithelial cells IEC-6 by affecting the expression of intestinal glucose transporters. (Source: Nutrition Research)
Source: Nutrition Research - February 18, 2016 Category: Nutrition Authors: Nazanin N. Abbasi, Peter P. Purslow, Susan M. Tosh, Marica Bakovic Source Type: research
Oat β-glucan depresses SGLT1- and GLUT2-mediated glucose transport in intestinal epithelial cells (IEC-6)
Oat β-glucan consumption is linked to reduced risk factors associated with diabetes and obesity by lowering glycemic response and serum level of low-density lipoproteins. The purpose of this study was to identify the mechanism of action of oat β-glucan at the interface between the gut wall and the lumen responsible for attenuating glucose levels. We proposed that viscous oat β-glucan acts as a physical barrier to glucose uptake in normally absorptive gut epithelial cells IEC-6 by affecting the expression of intestinal glucose transporters. (Source: Nutrition Research)
Source: Nutrition Research - February 17, 2016 Category: Nutrition Authors: Nazanin N. Abbasi, Peter P. Purslow, Susan M. Tosh, Marica Bakovic Tags: Original Research Source Type: research
The ACTN3 R577X polymorphism affects the lipid profile and the prognosis of nutritional intervention in HIV positive patients
The hypothesis of the present study is that the polymorphisms in the APOC3, CEPT, ACE and ACTN3 genes can affect the outcome of nutritional intervention and the plasma lipid profile of HIV+ patients. To test the hypothesis, genetic material was collected from buccal cells, and serum was collected for biochemical analysis. Sixty-five patients were analyzed. The incorporation of protease inhibitor (PI) was more frequent in women (77% vs. 33% in men). Nutritional intervention improved anthropometric parameters independent of the genotype. (Source: Nutrition Research)
Source: Nutrition Research - February 17, 2016 Category: Nutrition Authors: Laura C.R. Aranalde, Bruna S. Pederzoli, Thais Marten, Flavio C. Barros, Rossana P. Basso, Jussara M. Silveira, Sandra C. Valle, Simone Pieniz, Ronaldo C. Araujo, Edgar J. Paredes-Gamero, Ines Schadock, Augusto Schneider, Carlos C. Barros Source Type: research
Alternate-day fasting protects the livers of mice against high-fat diet-induced inflammation associated with the suppression of TLR-4/NF-κB signaling
Due to unhealthy lifestyles, a large number of people are suffering from hepatic lipid accumulation and nonalcoholic steatohepatitis. Calorie restriction (CR) is an effective nutritional intervention for preventing chronic disease. However, poor compliance with continuous calorie restriction limits its effectiveness. As an alternative to daily CR, alternate-day fasting (ADF) may be more effective. We hypothesized that ADF would improve obesity, hyperglycemia and insulin resistance and protect the liver against high-fat (HFD) diet-induced steatosis and inflammation. (Source: Nutrition Research)
Source: Nutrition Research - February 16, 2016 Category: Nutrition Authors: Wanwei Yang, Meng Cao, Xiaodong Mao, Xiao Wei, Xingjia Li, Guofang Chen, Jiaming Zhang, Zhiguo Wang, Jianfeng Shi, HouCai Huang, Xiaoming Yao, Chao Liu Source Type: research
Alternate-day fasting protects the livers of mice against high-fat diet–induced inflammation associated with the suppression of Toll-like receptor 4/nuclear factor κB signaling
Because of unhealthy lifestyles, a large number of people are suffering from hepatic lipid accumulation and nonalcoholic steatohepatitis. Energy restriction (ER) is an effective nutritional intervention for preventing chronic disease. However, poor compliance with continuous ER limits its effectiveness. As an alternative to daily ER, alternate-day fasting (ADF) may be more effective. We hypothesized that ADF would improve obesity, hyperglycemia, and insulin resistance and protect the liver against high-fat diet (HFD)–induced steatosis and inflammation. (Source: Nutrition Research)
Source: Nutrition Research - February 15, 2016 Category: Nutrition Authors: Wanwei Yang, Meng Cao, Xiaodong Mao, Xiao Wei, Xingjia Li, Guofang Chen, Jiaming Zhang, Zhiguo Wang, Jianfeng Shi, HouCai Huang, Xiaoming Yao, Chao Liu Tags: Original Research Source Type: research
Parenteral nutrition in short bowel syndrome patients, regardless of its duration, increases serum proinflammatory cytokines
Short bowel syndrome is a severe malabsorption disorder and prolonged parenteral nutrition is essential for survival in some cases. Among the undesirable effects of long-term parenteral nutrition are an increase in proinflammatory cytokines. The aim of the present study was to measure the serum levels of interleukin 6, interleukin 10, tumor necrosis factor alpha, and transforming growth factor beta, in patients with short bowel syndrome on cyclic parenteral nutrition and patients who had previously received but no longer require parenteral nutrition. (Source: Nutrition Research)
Source: Nutrition Research - February 2, 2016 Category: Nutrition Authors: Letícia Bizari, Andressa Feijó da Silva Santos, Norma Tiraboschi Foss, Júlio Sérgio Marchini, Vivian Marques Miguel Suen Tags: Communication Source Type: research
Mulberry ethanol extract attenuates hepatic steatosis and insulin resistance in high-fat diet-fed mice
In this study, we developed a hypothesis that mulberry exerted beneficial effects on metabolic disorders and evaluated the influence of the mulberry ethanol extract (MEE) on high-fat diet-induced hepatic steatosis and insulin resistance in mice. Thirty-six male C57BL/6J mice were assigned into three groups and fed either a low-fat diet or a high-fat diet with or without supplementation with MEE. (Source: Nutrition Research)
Source: Nutrition Research - February 1, 2016 Category: Nutrition Authors: Haizhao Song, Jia Lai, Qiong Tang, Xiaodong Zheng Source Type: research
Mulberry ethanol extract attenuates hepatic steatosis and insulin resistance in high-fat diet–fed mice
In this study, we developed a hypothesis that mulberry exerted beneficial effects on metabolic disorders and evaluated the influence of the mulberry ethanol extract (MEE) on high-fat diet–induced hepatic steatosis and insulin resistance in mice. Thirty-six male C57BL/6J mice were assigned into 3 groups and fed either a low-fat diet or a high-fat diet with or without supplementation with MEE. (Source: Nutrition Research)
Source: Nutrition Research - January 31, 2016 Category: Nutrition Authors: Haizhao Song, Jia Lai, Qiong Tang, Xiaodong Zheng Tags: Original Research Source Type: research
Umbilical cord blood telomere length and folate levels – a potential pathway for fetal re-programming
The objective of this study was to investigate the relationship between fetal red blood cell (RBC) folate levels, a surrogate measure for maternal folate levels, and TL. We hypothesized umbilical cord RBC folate concentrations would positively correlate with fetal telomere length. Data for this analysis were collected as part of a prospective cohort study which recruited pregnant women upon admission into labor and delivery. (Source: Nutrition Research)
Source: Nutrition Research - January 30, 2016 Category: Nutrition Authors: Adetola F. Louis-Jacques, Hamisu M. Salihu, Lindsey M. King, Arnut Paothong, Rachel G. Sinkey, Anupam Pradhan, Bridget M. Riggs, Erin M. Siegel, Jason L. Salemi, Valerie E. Whiteman Tags: Original Research Source Type: research
A positive association between umbilical cord RBC folate and fetal TL at birth supports a potential for fetal reprogramming
The objective of this study was to investigate the relationship between fetal red blood cell (RBC) folate levels, a surrogate measure for maternal folate levels, and TL. We hypothesized that umbilical cord RBC folate concentrations would positively correlate with fetal TL. Data for this analysis were collected as part of a prospective cohort study that recruited pregnant women upon admission into labor and delivery. (Source: Nutrition Research)
Source: Nutrition Research - January 29, 2016 Category: Nutrition Authors: Adetola F. Louis-Jacques, Hamisu M. Salihu, Lindsey M. King, Arnut Paothong, Rachel G. Sinkey, Anupam Pradhan, Bridget M. Riggs, Erin M. Siegel, Jason L. Salemi, Valerie E. Whiteman Tags: Original Research Source Type: research
Umbilical cord blood telomere length and folate levels—a potential pathway for fetal reprogramming
The objective of this study was to investigate the relationship between fetal red blood cell (RBC) folate levels, a surrogate measure for maternal folate levels, and TL. We hypothesized that umbilical cord RBC folate concentrations would positively correlate with fetal TL. Data for this analysis were collected as part of a prospective cohort study that recruited pregnant women upon admission into labor and delivery. (Source: Nutrition Research)
Source: Nutrition Research - January 29, 2016 Category: Nutrition Authors: Adetola F. Louis-Jacques, Hamisu M. Salihu, Lindsey M. King, Arnut Paothong, Rachel G. Sinkey, Anupam Pradhan, Bridget M. Riggs, Erin M. Siegel, Jason L. Salemi, Valerie E. Whiteman Tags: Original Research Source Type: research
Early sugar-sweetened beverage consumption frequency is associated with poor quality of later food and nutrient intake patterns among Japanese young children: the Osaka Maternal and Child Health Study
Evidence from Western countries shows that higher consumption of sugar-sweetened beverages (SSBs) is associated with lower quality of young children’s diets, but little is known about these relations in non-Western countries with relatively low consumption levels of SSBs. We hypothesized that SSB consumption in infancy would be associated with poor quality of later food and nutrient intake patterns among Japanese young children. The study subjects were 493 Japanese mother-child pairs from a prospective birth cohort study. (Source: Nutrition Research)
Source: Nutrition Research - January 29, 2016 Category: Nutrition Authors: Hitomi Okubo, Yoshihiro Miyake, Satoshi Sasaki, Keiko Tanaka, Yoshio Hirota Source Type: research
