Nutritional and exercise interventions variably affect estrogen receptor expression in the adipose tissue of male rats
Energy-dense food consumption and lack of physical activity are implicated in the development of the current obesity epidemic. The role of estrogen in adiposity and fuel partitioning is mediated mainly though the estrogen receptor alpha (ERα) isoform. We hypothesized that nutritional adaptation and exercise training, either individually or combined, could impact ERα expression in adipose tissue relative to glucose tolerance. Seventy-two Wistar rats were submitted to a high-fat, high-sucrose diet (HF-HS) for 16weeks. (Source: Nutrition Research)
Source: Nutrition Research - December 7, 2015 Category: Nutrition Authors: Lore Metz, Maude Gerbaix, Aurélie Masgrau, Christelle Guillet, Stéphane Walrand, Nathalie Boisseau, Yves Boirie, Daniel Courteix Source Type: research
Modification of a traditional breakfast leads to increased satiety along with attenuated plasma increments of glucose, C-peptide, insulin, and GIP in humans
The objectives of this crossover trial were to examine satiety, glycemic-insulinemic response, and plasma peptide levels in response to two different recommended diabetes diets with equivalent energy content. One traditional reference breakfast and one test breakfast, with lower carbohydrate and higher fat and protein content, were randomly administered to healthy volunteers (8 men, 12 women). (Source: Nutrition Research)
Source: Nutrition Research - December 7, 2015 Category: Nutrition Authors: Bodil Ohlsson, Peter Höglund, Bodil Roth, Gassan Darwiche Source Type: research
OK67 ameliorates high-fat diet–induced blood glucose intolerance and obesity in mice by inhibiting gut microbiota lipopolysaccharide production and inducing colon tight junction protein expression
A high-fat diet (HFD) induces obesity and the associated increases in blood glucose and inflammation through changes in gut microbiota, endotoxemia, and increased gut permeability. To counteract this, researchers have suggested that the use of probiotics that suppress production of proinflammatory lipopolysaccharide (LPS). Here, we tested whether Lactobacillus sakei OK67, which inhibits gut microbiota LPS production selected from among the lactic acid bacteria isolated from kimchi, exerted antihypoglycemic or anti-inflammatory effects in HFD-fed mice. (Source: Nutrition Research)
Source: Nutrition Research - December 3, 2015 Category: Nutrition Authors: Su-Min Lim, Jin-Ju Jeong, Kyung Hee Woo, Myung Joo Han, Dong-Hyun Kim Tags: Original Research Source Type: research
OK67 ameliorates high-fat diet-induced blood glucose intolerance and obesity in mice by inhibiting gut microbiota LPS production and inducing colon tight junction protein expression
A high-fat diet (HFD) induces obesity and the associated increases in blood glucose and inflammation through changes in gut microbiota, endotoxemia, and increased gut permeability. To counteract this, researchers have suggested that the use of probiotics that suppress production of pro-inflammatory lipopolysaccharide (LPS). Here, we tested whether Lactobacillus sakei OK67, which inhibits gut microbiota LPS production selected from among the lactic acid bacteria isolated from kimchi, exerted anti-hypoglycemic or anti-inflammatory effects in HFD-fed mice. (Source: Nutrition Research)
Source: Nutrition Research - December 3, 2015 Category: Nutrition Authors: Sumin Lim, Jin-Ju Jeong, Kyung Hee Woo, Myung Joo Han, Dong-Hyun Kim Source Type: research
420 and fish oil enhance intestinal epithelial integrity in Caco-2 cells
Increased intestinal permeability is a predisposing factor for low-grade inflammation–associated conditions, including obesity and type 2 diabetes. Dietary components may influence intestinal barrier integrity. We hypothesized that the dietary supplements Bifidobacterium lactis 420, Lactobacillus rhamnosus HN001, and fish oil have beneficial impacts on intestinal barrier integrity. In addition, we hypothesized that the coadministration of these components results in synergistic benefits to the integrity of the intestinal barrier. (Source: Nutrition Research)
Source: Nutrition Research - November 27, 2015 Category: Nutrition Authors: Kati Mokkala, Kirsi Laitinen, Henna Röytiö Tags: Original Research Source Type: research
