Dietary butyrylated high amylose starch reduces azoxymethane-induced colonic O6-methylguanine adducts in rats as measured by immunohistochemistry and high pressure liquid chromatography
In this study, we hypothesized that a dietary intervention that specifically delivers butyrate to the large bowel (notably butyrylated high amylose maize starch, HAMSB) would reduce colonic levels of O6MeG in rats, shortly after exposure to the DNA alkylating agent azoxymethane (AOM) when compared to a low amylose maize starch (LAMS). (Source: Nutrition Research)
Source: Nutrition Research - June 6, 2016 Category: Nutrition Authors: Richard K. Le Leu, Benjamin L. Scherer, Mark T. Mano, Jean M. Winter, Tamsin Lannagan, Richard J. Head, Trevor Lockett, Julie M. Clarke Tags: Original Research Source Type: research
The new total Western diet for rodents does not induce an overweight phenotype or alter parameters of metabolic syndrome in mice
In this study, we determined the impact of the total Western diet for rodents and its macro- and micronutrient components on weight gain and biomarkers of metabolic function in mice compared to a 45% fat diet-induced obesity (DIO) diet and the standard AIN93G diet. We hypothesized that mice fed the TWD would have increased body fat with indicators of metabolic syndrome similar to mice consuming the DIO diet. As expected, DIO-fed mice acquired a metabolic syndrome phenotype typified by increased energy intake, increased body weight gain, increased fat mass, higher fasting glucose, impaired glucose tolerance, and higher plas...
Source: Nutrition Research - June 4, 2016 Category: Nutrition Authors: Stephany P. Monsanto, Korry J. Hintze, Robert E. Ward, Deanna P. Larson, Michael Lefevre, Abby D. Benninghoff Source Type: research
Maternal n-3 polyunsaturated fatty acid deprivation during pregnancy and lactation affects neurogenesis and apoptosis in adult offspring: associated with DNA methylation of brain-derived neurotrophic factor transcripts
In this study, we hypothesized that n-3 polyunsaturated fatty acid (PUFA) deficiency during pregnancy and lactation will make a lasting impact on brain neurogenesis and apoptosis of the adult offspring and that these harmful effects cannot be reversed by n-3 PUFA supplementation after weaning. Moreover, the underlying mechanisms may be attributable to the epigenetic changes of brain-derived neurotrophic factor (BDNF). C57BL/6J female mice were fed with n-3 PUFA-deficient diet (n-3 def) or n-3 PUFA-adequate diet (n-3 adq) throughout pregnancy and lactation. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Chaonan Fan, Huicong Fu, Hua Dong, Yuanyuan Lu, Yanfei Lu, Kemin Qi Source Type: research
Milk intake during pregnancy is inversely associated with the risk of postpartum depressive symptoms in Japan: The Kyushu Okinawa Maternal and Child Health Study
Only one epidemiological study has investigated the association between dairy product intake during pregnancy and postpartum depressive symptoms. Epidemiological evidence on the relationships between calcium and vitamin D intake during pregnancy and postpartum depressive symptoms is also lacking. The present prospective study examined these issues in Japan. Study subjects were 1319 women. During pregnancy, dietary intake during the preceding month was assessed using a self-administered diet history questionnaire in the baseline survey. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Shinya Furukawa, Masashi Arakawa Source Type: research
Lower hepatic iron storage associated with obesity in mice can be restored by decreasing body fat mass through feeding a low-fat diet
High-fat diet (HFD)-induced obesity has been reported to result in low hepatic iron storage. In the current study, we tested the hypothesis that these obesity-related changes in hepatic iron status could be reversed by decreasing adiposity by feeding a low-fat diet. Five-week-old C57BL/6 mice were assigned to three groups: The LL group was fed a control diet for 31 weeks, the HH group was fed a HFD for 31 weeks, and the HL group was fed the HFD for 15 weeks and then switched to the control diet for 16 weeks. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Hak Chung, Dayong Wu, Donald Smith, SiminNikbin Meydani, Sung Nim Han Source Type: research
Medium-chain triglycerides promote macrophage reverse cholesterol transport and improve atherosclerosis in ApoE-deficient mice fed a high-fat diet
We previously observed that medium-chain triglycerides (MCTs) could reduce body fat mass and improve the metabolism of cholesterol. We hypothesized that MCTs can improve atherosclerosis by promoting the reverse cholesterol transport (RCT) process. Therefore, the objective of this study was to investigate the roles of MCTs in macrophage RCT and the progression of atherosclerosis. To test this hypothesis, 30 4-week-old ApoE-deficient (ApoE −/−) mice were randomly divided into 2 groups and fed a diet of 2% MCTs or long-chain triglycerides (LCTs) for 16 weeks. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Xinsheng Zhang, Yong Zhang, Yinghua Liu, Jin Wang, Qing Xu, Xiaoming Yu, Xueyan Yang, Zhao Liu, Changyong Xue Source Type: research
Maternal n-3 PUFA deprivation during pregnancy and lactation affects neurogenesis and apoptosis in adult offspring: associated with DNA methylation of BDNF transcripts
In this study, we hypothesized that n-3 polyunsaturated fatty acid (PUFA) deficiency during pregnancy and lactation will make a lasting impact on brain neurogenesis and apoptosis of the adult offspring, and these harmful effects cannot be reversed by n-3 PUFA supplementation after weaning. Moreover, the underlying mechanisms may be attributable to the epigenetic changes of brain derived neurotrophic factor (BDNF). C57BL/6 J female mice were fed with n-3 PUFA-deficient diet (n-3 def) or n-3 PUFA adequate diet (n-3 adq) throughout pregnancy and lactation. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Chaonan Fan, Huicong Fu, Hua Dong, Yuanyuan Lu, Yanfei Lu, Kemin Qi Source Type: research
Milk intake during pregnancy is inversely associated with the risk of postpartum depressive symptoms in Japan: The Kyushu Okinawa Maternal and Child Health Study
Only one epidemiological study has investigated the association between dairy product intake during pregnancy and postpartum depressive symptoms. Epidemiological evidence on the relationships between calcium and vitamin D intake during pregnancy and postpartum depressive symptoms is also lacking. The present prospective study examined these issues in Japan. Study subjects were 1319 women. During pregnancy, dietary intake during the preceding month was assessed using a self-administered diet history questionnaire in the baseline survey. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Yoshihiro Miyake, Keiko Tanaka, Hitomi Okubo, Satoshi Sasaki, Shinya Furukawa, Masashi Arakawa Source Type: research
Lower hepatic iron storage associated with obesity in mice can be restored by decreasing body fat mass through feeding a low-fat diet
High-fat diet (HFD)-induced obesity has been reported to result in low hepatic iron storage. In the current study, we tested the hypothesis that these obesity-related changes in hepatic iron status could be reversed by decreasing adiposity by feeding a low-fat diet. Five-week-old C57BL/6 mice were assigned to three groups: The LL group was fed a control diet for 31 weeks, the HH group was fed a HFD for 31 weeks, and the HL group was fed the HFD for 15 weeks and then switched to the control diet for 16 weeks. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Hak Chung, Dayong Wu, Donald Smith, SiminNikbin Meydani, Sung Nim Han Source Type: research
Medium-chain triglycerides promote macrophage reverse cholesterol transport and improve atherosclerosis in ApoE-deficient mice fed a high-fat diet
We previously observed that medium-chain triglycerides (MCTs) could reduce body fat mass and improve the metabolism of cholesterol. We hypothesized that MCTs can improve atherosclerosis by promoting the reverse cholesterol transport (RCT) process. Therefore, the objective of this study was to investigate the roles of MCTs in macrophage RCT and the progression of atherosclerosis. To test this hypothesis, 30 4-week-old ApoE-deficient (ApoE−/−) mice were randomly divided into 2 groups and fed a diet of 2% MCTs or long-chain triglycerides (LCTs) for 16 weeks. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Xinsheng Zhang, Yong Zhang, Yinghua Liu, Jin Wang, Qing Xu, Xiaoming Yu, Xueyan Yang, Zhao Liu, Changyong Xue Source Type: research
Maternal n-3 PUFA deprivation during pregnancy and lactation affects neurogenesis and apoptosis in adult offspring: associated with DNA methylation of BDNF transcripts
In this study, we hypothesized that n-3 polyunsaturated fatty acid (PUFA) deficiency during pregnancy and lactation will make a lasting impact on brain neurogenesis and apoptosis of the adult offspring, and these harmful effects cannot be reversed by n-3 PUFA supplementation after weaning. Moreover, the underlying mechanisms may be attributable to the epigenetic changes of brain derived neurotrophic factor (BDNF). C57BL/6 J female mice were fed with n-3 PUFA-deficient diet (n-3 def) or n-3 PUFA adequate diet (n-3 adq) throughout pregnancy and lactation. (Source: Nutrition Research)
Source: Nutrition Research - June 2, 2016 Category: Nutrition Authors: Chaonan Fan, Huicong Fu, Hua Dong, Yuanyuan Lu, Yanfei Lu, Kemin Qi Source Type: research
Conventional foods, followed by dietary supplements and fortified foods, are the key sources of vitamin D, vitamin B6, and selenium intake in Dutch participants of the NU-AGE study
With aging, energy needs decrease, necessitating a more nutrient-dense diet to meet nutritional needs. To bridge this gap, the use of nutrient-dense foods, fortified foods, and dietary supplements can be important. This observational study aims to describe current micronutrient intakes of Dutch elderly and to identify the contribution of nutrient-dense foods, fortified foods, and dietary supplements to the intake of micronutrients that are often inadequately consumed in Dutch elderly. Data of 245 Dutch volunteers from the NU-AGE study aged 65 to 80 years were used. (Source: Nutrition Research)
Source: Nutrition Research - May 26, 2016 Category: Nutrition Authors: Agnes A.M. Berendsen, Lilou E.L.M. van Lieshout, Ellen G.H.M. van den Heuvel, Christophe Matthys, Szabolcs P éter, Lisette C.P.G.M. de Groot Source Type: research
Conventional foods, followed by dietary supplements and fortified foods, are the key sources of vitamin D, vitamin B6 and selenium intake in Dutch participants of the NU-AGE study
With aging, energy needs decrease, necessitating a more nutrient dense diet in order to meet nutritional needs. To bridge this gap, the use of nutrient dense foods, fortified foods and dietary supplements can be important. This observational study aims to describe current micronutrient intakes of Dutch elderly and to identify the contribution of nutrient dense foods, fortified foods and dietary supplements to the intake of micronutrients that are often inadequately consumed in Dutch elderly. Data of 245 Dutch volunteers from the NU-AGE study aged 65–80 years were used. (Source: Nutrition Research)
Source: Nutrition Research - May 26, 2016 Category: Nutrition Authors: Agnes A.M. Berendsen, Lilou E.L.M. van Lieshout, Ellen G.H.M. van den Heuvel, Christophe Matthys, Szabolcs Péter, Lisette C.P.G.M. de Groot Source Type: research
