Journal of the Renin-Angiotensin-Aldosterone System : JRAAS This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Therapeutic effect of renin angiotensin system inhibitors on liver fibrosis
Conclusions: Renin angiotensin system inhibitor therapy results in a reduction in liver fibrosis score and liver fibrosis area in patients with hepatic fibrosis with good safety profile. However, randomized controlled trials of high-quality will clarify the effectiveness of renin angiotensin system inhibitors on liver fibrosis. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - March 22, 2016 Category: Biomedical Science Authors: Zhu, Q., Li, N., Li, F., Zhou, Z., Han, Q., Lv, Y., Sang, J., Liu, Z. Tags: Original Article Source Type: research

The association of angiotensin-converting enzyme gene insertion/deletion polymorphisms with adaptation to high altitude: A meta-analysis
Conclusions: Our findings suggested that the DD genotype of ACE is a risk factor for HA maladaptation and that the presence of fewer ACE DD allele carriers in a population indicates a greater ability of that population to adapt to HA. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - March 22, 2016 Category: Biomedical Science Authors: Wang, Y., Lu, H., Chen, Y., Luo, Y. Tags: Original Article Source Type: research

The potential role of atrial natriuretic peptide in the effects of Angiotensin-(1-7) in a chronic atrial tachycardia canine model
Conclusion: Ang-(1–7) prevented atrial structural and electrical remodeling induced by ARP. Furthermore, Ang-(1–7) promoted ANP secretion, and ANP played a crucial role in the cardiac protection of the former. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - March 22, 2016 Category: Biomedical Science Authors: Zhao, J., Liu, T., Liu, E., Li, G., Qi, L., Li, J. Tags: Original Article Source Type: research

Evaluation of the (1-24) adrenocorticotropin stimulation test for the diagnosis of primary aldosteronism
Conclusions: The ACTH test may not be useful as a screening or confirmatory test, but the test may be useful for differentiating between patients with confirmed PA and the rest of the cohort. The positive finding of the ACTH test may at least support a higher likelihood of lateralizing on adrenal venous sampling. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - March 22, 2016 Category: Biomedical Science Authors: Terui, K., Kageyama, K., Nigawara, T., Moriyama, T., Sakihara, S., Takayasu, S., Tsushima, Y., Watanki, Y., Yamagata, S., Sugiyama, A., Murasawa, S., Nakada, Y., Suda, T., Daimon, M. Tags: Original Article Source Type: research

Analysis of insertion/deletion polymorphisms of the angiotensin converting enzyme gene in Malaysian end-stage renal disease patients
Conclusion: The findings of this study indicate that I/D polymorphisms of the ACE gene are a useful marker and are likely to play a major role in determining genetic susceptibility to ESRD in the Malaysian population. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Ali, A., Vasudevan, R., Ismail, P., Thiam Seong, C. L., Chakravarthi, S. Tags: Original Articles Source Type: research

Treatment with aliskiren ameliorates tacrolimus-induced nephrotoxicity in rats
Conclusion: These results suggest that aliskiren has protective effects against tacrolimus-induced nephrotoxicity; implying that renin inhibitor may counteract nephrotic syndrome associated with immunosuppressant use. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Al-Harbi, N. O., Imam, F., Al-Harbi, M. M., Iqbal, M., Nadeem, A., Al-Shahrah, O. A., Korashy, H. M., Al-Hosaini, K. A., Ahmed, M., Bahashwar, S. Tags: Original Articles Source Type: research

The relationship between three X-linked genes and the risk for hypertension among northeastern Han Chinese
Conclusion: Our findings demonstrate that genetic defects in AGTR2 and apelin genes by themselves may play an independent leading role in determining susceptibility to hypertension in both genders. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Li, J., Feng, M., Wang, Y., Li, Y., Zhang, Y., Li, L., Xiong, J., Lu, C., Wang, B., Cheng, Z., Tang, B., Niu, W. Tags: Original Articles Source Type: research

The relationship between the polymorphisms of the CYP17A1 gene and hypertension: A meta-analysis
Conclusions: The present meta-analysis confirmed the significant association between a polymorphism of the CYP17A1 gene and hypertension susceptibility. The CYP17A1 A allele should be considered a risk factor for hypertension. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Dai, C.-F., Xie, X., Ma, Y.-T., Yang, Y.-N., Li, X.-M., Fu, Z.-Y., Liu, F., Chen, B.-D., Gai, M.-T. Tags: Original Articles Source Type: research

The relationship between angiotensin-converting enzyme gene insertion/deletion polymorphism and digestive cancer risk: Insights from a meta-analysis
Conclusion: Our findings suggested that ACE gene I allele might be a protective factor against gastric cancer, necessitating further confirmation in large, population-based studies. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Yang, H., Cai, C., Ye, L., Rao, Y., Wang, Q., Hu, D., Huang, X. Tags: Original Articles Source Type: research

The ratios of aldosterone / plasma renin activity (ARR) versus aldosterone / direct renin concentration (ADRR)
Primary aldosteronism (PA) is estimated to occur in 5–12% of patients with hypertension. Assessment of aldosterone / plasma renin activity (PRA) ratio (ARR) has been used as a screening test in patients suspected of PA. Direct determination of renin (DRC) and calculation of aldosterone / direct renin concentration ratio (ADRR) could be similarly useful for screening patients suspected of PA. The study included 62 patients with indication for evaluation of the renin-angiotensin-aldosterone system and 35 healthy volunteers. In all participants we measured concentrations of serum aldosterone, plasma direct renin, and PR...
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Glinicki, P., Jeske, W., Bednarek-Papierska, L., Kruszynska, A., Gietka-Czernel, M., Rosłonowska, E., Słowinska-Srzednicka, J., Kasperlik-Załuska, A., Zgliczynski, W. Tags: Original Articles Source Type: research

The microRNA-132/212 family fine-tunes multiple targets in Angiotensin II signalling in cardiac fibroblasts
Conclusion: We here report novel insight of an extensive network of molecular pathways that fine-tuned by miR-132/212, suggesting a role for this miRNA family as master signalling switches in cardiac fibroblasts. Our data underscore the potential for miRNA tools to manipulate a large array of molecules and thereby control biological function. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Eskildsen, T. V., Schneider, M., Sandberg, M. B., Skov, V., Bronnum, H., Thomassen, M., Kruse, T. A., Andersen, D. C., Sheikh, S. P. Tags: Original Articles Source Type: research

The insertion and deletion (I28005D) polymorphism of the angiotensin I converting enzyme gene is a risk factor for osteoarthritis in an Asian Indian population
Conclusion: The ACE gene polymorphism I28005D was found to be associated with primary knee OA in Asian Indian populations. This is the first study in India to report that the ACE gene polymorphism is a risk factor for early onset primary knee OA. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Poornima, S., Subramanyam, K., Khan, I. A., Hasan, Q. Tags: Original Articles Source Type: research

The efficacy and mechanism of dexmedetomidine in myocardial apoptosis via the renin-angiotensin-aldosterone system
Conclusions: The results show that dexmedetomidine (DEX) produces cardioprotection against myocardial apoptosis injury. DEX is not only a useful sedative, but also plays a pivotal role in anesthetic cardioprotection. The potential benefits of DEX protection in high risk cardiovascular patients undergoing surgery are enormous. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Wang, H., Zhang, S., Xu, S., Zhang, L. Tags: Original Articles Source Type: research

The effects of siRNA-silenced TRPC6 on podocyte autophagy and apoptosis induced by AngII
Conclusion: the data suggest that AngII can lead to podocyte injury. Autophagy may have beneficial effects in preventing the progression of proteinuria. This study provides some new clues for further exploring the occurrence of podocyte injury and the development mechanism of proteinuria. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Shengyou, Y., Li, Y. Tags: Original Articles Source Type: research

The effect of renin-angiotensin system inhibitors on intact parathyroid hormone levels in peritoneal dialysis patients
Conclusion: RASI use may be associated with a lower iPTH level in CAPD patients, although the underlying mechanism requires further study. (Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS)
Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Gao, L., Wang, Z., Feng, S., Jiang, S., Ouyang, H., Shi, Y., Shen, H. Tags: Original Articles Source Type: research