Treatment with aliskiren ameliorates tacrolimus-induced nephrotoxicity in rats

Conclusion:
These results suggest that aliskiren has protective effects against tacrolimus-induced nephrotoxicity; implying that renin inhibitor may counteract nephrotic syndrome associated with immunosuppressant use.

Source: Journal of the Renin-Angiotensin-Aldosterone System : JRAAS - December 23, 2015 Category: Biomedical Science Authors: Al-Harbi, N. O., Imam, F., Al-Harbi, M. M., Iqbal, M., Nadeem, A., Al-Shahrah, O. A., Korashy, H. M., Al-Hosaini, K. A., Ahmed, M., Bahashwar, S. Tags: Original Articles Source Type: research